AAV vectors transduce hepatocytes in vivo as efficiently in cirrhotic as in healthy rat livers (Q45872572)

17 December 2017

title

AAV vectors transduce hepatocytes in vivo as efficiently in cirrhotic as in healthy rat livers (English)

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17 December 2017

Carlos M Rodriguez-Ortigosa

main subject

liver cirrhosis

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author

3

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17 December 2017

Jesús Prieto

7

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17 December 2017

Puri Fortes

8

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author name string

L Sobrevals

1

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17 December 2017

M Enguita

2

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17 December 2017

J Gonzalez-Rojas

4

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P Alzaguren

5

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N Razquin

6

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publication date

18 August 2011

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17 December 2017

published in

Gene Therapy

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17 December 2017

volume

19

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issue

4

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page(s)

411-417

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Mechanisms of disease: Mechanisms of hepatic fibrosis and therapeutic implications

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1 reference

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Hepatocyte nuclear factor 4alpha attenuates hepatic fibrosis in rats

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Superoxide dismutase gene transfer reduces portal pressure in CCl4 cirrhotic rats with portal hypertension.

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Dual Therapeutic Effects of Interferon-α Gene Therapy in a Rat Hepatocellular Carcinoma Model With Liver Cirrhosis

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Adenovirus-mediated inhibition of SPARC attenuates liver fibrosis in rats

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Adenovirus-mediated expression of BMP-7 suppresses the development of liver fibrosis in rats

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Adeno-associated virus mediated interferon-gamma inhibits the progression of hepatic fibrosis in vitro and in vivo

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Liver transduction with a simian virus 40 vector encoding insulin-like growth factor I reduces hepatic damage and the development of liver cirrhosis

21 January 2018

1 reference

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Cirrhotic rat livers with extensive fibrosis can be safely transduced with clinical-grade adenoviral vectors. Evidence of cirrhosis reversion

21 January 2018

1 reference

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Unexpected pulmonary uptake of adenovirus vectors in animals with chronic liver disease

21 January 2018

1 reference

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The role of liver sinusoidal cells in hepatocyte-directed gene transfer

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Clinical gene therapy using recombinant adeno-associated virus vectors

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Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis

21 January 2018

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Adeno-associated virus terminal repeat (TR) mutant generates self-complementary vectors to overcome the rate-limiting step to transduction in vivo

21 January 2018

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Rapid and highly efficient transduction by double-stranded adeno-associated virus vectors in vitro and in vivo

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Self-complementary adeno-associated virus vectors containing a novel liver-specific human factor IX expression cassette enable highly efficient transduction of murine and nonhuman primate liver

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Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector

21 January 2018

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Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain

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AAV serotype 2 vectors preferentially integrate into active genes in mice

21 January 2018

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Adeno-associated virus vector serotypes mediate sustained correction of bilirubin UDP glucuronosyltransferase deficiency in rats

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Transplanted endothelial progenitor cells ameliorate carbon tetrachloride-induced liver cirrhosis in rats

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In vitro and in vivo comparative study of chimeric liver-specific promoters

21 January 2018

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Sustained enzymatic correction by rAAV-mediated liver gene therapy protects against induced motor neuropathy in acute porphyria mice.

21 January 2018

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Adenovirus-mediated gene transfer of interferon α improves dimethylnitrosamine-induced liver cirrhosis in rat model

21 January 2018

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Perfusion imaging of the liver: current challenges and future goals

21 January 2018

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Adenovirus virus-associated RNA is processed to functional interfering RNAs involved in virus production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.119

Adenovirus VA RNA-derived miRNAs target cellular genes involved in cell growth, gene expression and DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.119

Adenovirus-mediated gene expression in the septal cells of cirrhotic rat livers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.119

inferred from DOI database lookup

7 January 2021

based on heuristic

Isolation of rat hepatocytes with EDTA and their metabolic functions in primary culture

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.119

inferred from DOI database lookup

7 January 2021

based on heuristic

Isolation and culture of hepatic lipocytes, Kupffer cells, and sinusoidal endothelial cells by density gradient centrifugation with Stractan

1 reference

https://api.crossref.org/works/10.1038%2FGT.2011.119

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/GT.2011.119

1 reference

17 December 2017

Dimensions Publication ID

1034303344

0 references

1 reference

17 December 2017