Flt-3 ligand as adjuvant for DNA vaccination augments immune responses but does not skew TH1/TH2 polarization (Q45874543)

17 December 2017

title

Flt-3 ligand as adjuvant for DNA vaccination augments immune responses but does not skew TH1/TH2 polarization (English)

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17 December 2017

O Schmetzer

5

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author name string

J Westermann

1

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17 December 2017

T Nguyen-Hoai

2

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17 December 2017

A Mollweide

3

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17 December 2017

G Richter

4

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17 December 2017

H-J Kim

6

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17 December 2017

Th Blankenstein

7

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17 December 2017

B Dörken

8

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17 December 2017

A Pezzutto

9

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17 December 2017

publication date

1 July 2004

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17 December 2017

published in

Gene Therapy

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17 December 2017

volume

11

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17 December 2017

issue

13

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17 December 2017

page(s)

1048-1056

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17 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.gt.3302261

exact match

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cites work

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Predominant role for directly transfected dendritic cells in antigen presentation to CD8+ T cells after gene gun immunization.

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Prophylactic tumor vaccination: comparison of effector mechanisms initiated by protein versus DNA vaccination.

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Dendritic cells in immunity and tolerance-do they display opposite functions?

21 January 2018

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Flt3 ligand antitumor activity in a murine breast cancer model: a comparison with granulocyte-macrophage colony-stimulating factor and a potential mechanism of action

21 January 2018

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Generation of potent and specific cellular immune responses via in vivo stimulation of dendritic cells by pNGVL3-hFLex plasmid DNA and immunogenic peptides.

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Dendritic cells engineered to express the Flt3 ligand stimulate type I immune response, and induce enhanced cytoxic T and natural killer cell cytotoxicities and antitumor immunity

21 January 2018

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Reduced herpes simplex virus type 1 latency in Flt-3 ligand-treated mice is associated with enhanced numbers of natural killer and dendritic cells

21 January 2018

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Prevention of peripheral tolerance by a dendritic cell growth factor: flt3 ligand as an adjuvant

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Adjuvant effect of a Flt3 ligand (FL) gene-transduced xenogeneic cell line in a murine colon cancer model

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Intramuscular co-injection of naked DNA encoding HBV core antigen and Flt3 ligand suppresses anti-HBc antibody response

21 January 2018

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The use of Flt3 ligand as an adjuvant for hepatitis B vaccination of healthy adults

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Impact of the tumor microenvironment on host infiltrating cells and the efficacy of flt3-ligand combination immunotherapy evaluated in a treatment model of mouse prostate cancer

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Flexibility of mouse classical and plasmacytoid-derived dendritic cells in directing T helper type 1 and 2 cell development: dependency on antigen dose and differential toll-like receptor ligation

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The ability of murine dendritic cell subsets to direct T helper cell differentiation is dependent on microbial signals

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DNA-based immunization by in vivo transfection of dendritic cells

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7 January 2021

Novel phenotype associated with in vivo activated CTL precursors

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7 January 2021

Co-expression of granulocyte-macrophage colony-stimulating factor with antigen enhances humoral and tumor immunity after DNA vaccination

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7 January 2021

Flt3 ligand induces tumor regression and antitumor immune responses in vivo

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7 January 2021

In vitro tumor-pulsed or in vivo Flt3 ligand-generated dendritic cells provide protection against acute myelogenous leukemia in nontransplanted or syngeneic bone marrow-transplanted mice

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7 January 2021

Pilot study of an HLA-A2 peptide vaccine using flt3 ligand as a systemic vaccine adjuvant

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7 January 2021

FLT3 ligand promotes engraftment of allogeneic hematopoietic stem cells without significant graft-versus-host disease

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7 January 2021

Kinetics of dendritic cell activation: impact on priming of TH1, TH2 and nonpolarized T cells

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7 January 2021

High antigen dose and activated dendritic cells enable Th cells to escape regulatory T cell-mediated suppression in vitro

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7 January 2021

In vivo manipulation of dendritic cells to induce therapeutic immunity

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7 January 2021

Functional skewing of bone marrow-derived dendritic cells by Th1- or Th2-inducing cytokines

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7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3302261

1 reference

17 December 2017

Dimensions Publication ID

1009975738

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Fatcat ID

release_xfnigvvydbffxl6q3gbyjjuray

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/xfnigvvydbffxl6q3gbyjjuray

24 November 2022

mapped directly with Wikidata item

1 reference

17 December 2017