Genetic heterogeneity in the toxicity to systemic adenoviral gene transfer of interleukin-12. (Q45876479)

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6 November 2019

title

Genetic heterogeneity in the toxicity to systemic adenoviral gene transfer of interleukin-12 (English)

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6 November 2019

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8

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6 November 2019

Bruno Sangro

6

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6 November 2019

author name string

Mazzolini G

1

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6 November 2019

Narvaiza I

2

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6 November 2019

Pérez-Diez A

3

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6 November 2019

Rodriguez-Calvillo M

4

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Qian C

5

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6 November 2019

Ruiz J

7

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6 November 2019

Melero I

9

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6 November 2019

publication date

1 February 2001

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6 November 2019

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6 November 2019

volume

8

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6 November 2019

issue

4

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6 November 2019

page(s)

259-267

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IL-12 as an adjuvant for cell-mediated immunity

6 November 2019

cites work

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Tumor cell responses to IFNgamma affect tumorigenicity and response to IL-12 therapy and antiangiogenesis

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Murine macrophages secrete interferon gamma upon combined stimulation with interleukin (IL)-12 and IL-18: A novel pathway of autocrine macrophage activation

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Interleukin 12-dependent interferon gamma production by CD8alpha+ lymphoid dendritic cells

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Adenovirus-mediated interleukin-12 gene therapy for metastatic colon carcinoma

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Herpes simplex virus as an in situ cancer vaccine for the induction of specific anti-tumor immunity

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The toxicology of interleukin-12: a review

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Regulation of interferon-gamma production by IL-12 and IL-18.

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Potent antitumor effects mediated by local expression of the mature form of the interferon-gamma inducing factor, interleukin-18 (IL-18).

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The interleukin-12/interleukin-12-receptor system: role in normal and pathologic immune responses

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The regulation of immunity to Leishmania major

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Cellular responses to interferon-gamma

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Immune suppression by recombinant interleukin (rIL)-12 involves interferon gamma induction of nitric oxide synthase 2 (iNOS) activity: inhibitors of NO generation reveal the extent of rIL-12 vaccine adjuvant effect

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Adenoviral gene transfer of interleukin 12 into tumors synergizes with adoptive T cell therapy both at the induction and effector level

21 January 2018

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Regression of colon cancer and induction of antitumor immunity by intratumoral injection of adenovirus expressing interleukin-12.

21 January 2018

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NK1.1 cells express 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies.

21 January 2018

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Direct Intratumoral Injection of an Adenovirus Expressing Interleukin-12 Induces Regression and Long-Lasting Immunity That Is Associated with Highly Localized Expression of Interleukin-12

21 January 2018

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Antitumor activities of IL-12 and mechanisms of action.

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7 January 2021

Interleukin-12: a cytokine at the interface of inflammation and immunity

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7 January 2021

IL-12 Acts Directly on DC to Promote Nuclear Localization of NF-κB and Primes DC for IL-12 Production

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7 January 2021

Requirement for type 2 NO synthase for IL-12 signaling in innate immunity

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7 January 2021

Enhancement of anti-tumor immunity by injection of fibroblasts genetically engineered to produce IL-12 and to express CD70.

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7 January 2021

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7 January 2021

Interleukin-12: role of interferon-gamma in IL-12 adverse effects

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7 January 2021

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7 January 2021

Gene transfer and therapy with adenoviral vector in rats with diethylnitrosamine-induced hepatocellular carcinoma

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7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3301387

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11313799%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

6 November 2019

1025059424

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