Cytokine gene therapy of gliomas: effective induction of therapeutic immunity to intracranial tumors by peripheral immunization with interleukin-4 transduced glioma cells (Q45879265)

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English	Cytokine gene therapy of gliomas: effective induction of therapeutic immunity to intracranial tumors by peripheral immunization with interleukin-4 transduced glioma cells	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/11509946

Cytokine gene therapy of gliomas: effective induction of therapeutic immunity to intracranial tumors by peripheral immunization with interleukin-4 transduced glioma cells (English)

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/11509946

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Michael T Lotze

6

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Lotze MT

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/11509946

author name string

Okada H

1

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PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/11509946

Villa L

2

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/11509946

Attanucci J

3

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/11509946

Erff M

4

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/11509946

Fellows WK

5

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/11509946

Pollack IF

7

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Europe PubMed Central

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17 December 2017

http://europepmc.org/abstract/MED/11509946

Chambers WH

8

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17 December 2017

http://europepmc.org/abstract/MED/11509946

publication date

1 August 2001

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Europe PubMed Central

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17 December 2017

http://europepmc.org/abstract/MED/11509946

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/11509946

8

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/11509946

15

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/11509946

1157-1166

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/11509946

https://scigraph.springernature.com/pub.10.1038/sj.gt.3301496

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Gamma knife for glioma: selection factors and survival

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21 January 2018

Lymphocytic infiltrates in primary glioblastomas and recidivous gliomas. Incidence, fate, and relevance to prognosis in 228 operated cases

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Relationship of lymphocyte invasion and survival of brain tumor patients

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Effective cytokine gene therapy against an intracranial glioma using a retrovirally transduced IL-4 plus HSVtk tumor vaccine

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Bone marrow-derived dendritic cells pulsed with a tumor-specific peptide elicit effective anti-tumor immunity against intracranial neoplasms

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Subcutaneous vaccination with irradiated, cytokine-producing tumor cells stimulates CD8+ cell-mediated immunity against tumors located in the "immunologically privileged" central nervous system

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Inhibition of lymphocyte function by glioblastoma-derived transforming growth factor beta 2.

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Fas ligand expression by astrocytoma in vivo: maintaining immune privilege in the brain?

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Intratumoral LAK cell and interleukin-2 therapy of human gliomas.

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Induction of lethal experimental allergic encephalomyelitis in nonhuman primates and guinea pigs with human glioblastoma multiforme tissue

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Immunobiology of primary intracranial tumors. Part 7: Active immunization of patients with anaplastic human glioma cells: a pilot study.

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Immunobiology of primary intracranial tumors. Part 1: studies of the cellular and humoral general immune competence of brain-tumor patients

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Bone marrow-generated dendritic cells pulsed with tumor extracts or tumor RNA induce antitumor immunity against central nervous system tumors

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Treatment of intracranial gliomas with bone marrow-derived dendritic cells pulsed with tumor antigens

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Characterization and transduction of a retroviral vector encoding human interleukin-4 and herpes simplex virus-thymidine kinase for glioma tumor vaccine therapy

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21 January 2018

Limited efficacy of the HSV-TK/GCV system for gene therapy of malignant gliomas and perspectives for the combined transduction of the interleukin-4 gene

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21 January 2018

Treatment of intracranial gliomas in immunocompetent mice using herpes simplex viruses that express murine interleukins

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Gene therapy of experimental brain tumors using neural progenitor cells

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Treatment of established renal cancer by tumor cells engineered to secrete interleukin-4.

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Retroviral interleukin 4 gene transfer into an interleukin 4-dependent cell line results in autocrine growth but not in tumorigenicity

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IL-12 gene therapy using direct injection of tumors with genetically engineered autologous fibroblasts

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Interleukin-12 and B7.1 co-stimulation cooperate in the induction of effective antitumor immunity and therapy of established tumors.

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Cure of mice with established metastatic friend leukemia cell tumors by a combined therapy with tumor cells expressing both interferon-alpha 1 and herpes simplex thymidine kinase followed by ganciclovir

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Interferon-alpha gene therapy for cancer: retroviral transduction of fibroblasts and particle-mediated transfection of tumor cells are both effective strategies for gene delivery in murine tumor models

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Nonviral interferon alpha gene therapy inhibits growth of established tumors by eliciting a systemic immune response

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Interleukin-12-based immunotherapy against rat 9L glioma

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Eradication of established intracranial rat gliomas by transforming growth factor beta antisense gene therapy

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21 January 2018

Gene therapy of malignant gliomas: a phase I study of IL-4-HSV-TK gene-modified autologous tumor to elicit an immune response

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Characterization of a spontaneous murine astrocytoma and abrogation of its tumorigenicity by cytokine secretion

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Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: implications for clinical trials

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Effect of in situ retroviral interleukin-4 transfer on established intracranial tumors

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The paracrine role of tumour-derived mIL-4 on tumour-associated endothelium.

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Paracrine delivery of IL-12 against intracranial 9L gliosarcoma in rats.

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Effects of continuous localized infusion of granulocyte-macrophage colony-stimulating factor and inoculations of irradiated glioma cells on tumor regression.

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T helper cell type 1-associated and cytotoxic T lymphocyte-mediated tumor immunity is impaired in interleukin 4-deficient mice

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10.1038/SJ.GT.3301496

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/11509946

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/11509946

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