Transgenic pigs produce functional human factor VIII in milk (Q45883787)

17 December 2017

title

Transgenic pigs produce functional human factor VIII in milk (English)

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17 December 2017

author name string

Paleyanda RK

1

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17 December 2017

Velander WH

2

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17 December 2017

Lee TK

3

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17 December 2017

Scandella DH

4

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17 December 2017

Gwazdauskas FC

5

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17 December 2017

Knight JW

6

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17 December 2017

Hoyer LW

7

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17 December 2017

Drohan WN

8

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17 December 2017

Lubon H

9

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17 December 2017

publication date

1 October 1997

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17 December 2017

published in

Nature Biotechnology

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17 December 2017

volume

15

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17 December 2017

issue

10

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17 December 2017

page(s)

971-975

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17 December 2017

Characterization of dysfunctional factor VIII molecules

cites work

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https://api.crossref.org/works/10.1038%2FNBT1097-971

Causes of death in haemophilia

21 January 2018

1 reference

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Effect of von Willebrand factor coexpression on the synthesis and secretion of factor VIII in Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1097-971

Structure of human factor VIII

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1097-971

7 January 2021

Molecular cloning of a cDNA encoding human antihaemophilic factor

1 reference

https://api.crossref.org/works/10.1038%2FNBT1097-971

7 January 2021

Expression of active human factor VIII from recombinant DNA clones

1 reference

https://api.crossref.org/works/10.1038%2FNBT1097-971

7 January 2021

Stabilization of factor VIII in plasma by the von Willebrand factor. Studies on posttransfusion and dissociated factor VIII and in patients with von Willebrand's disease

1 reference

https://api.crossref.org/works/10.1038%2FNBT1097-971

7 January 2021

Characterization of the human factor VIII gene

1 reference

https://api.crossref.org/works/10.1038%2FNBT1097-971

7 January 2021

Construction and characterization of an active factor VIII variant lacking the central one-third of the molecule

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https://api.crossref.org/works/10.1038%2FNBT1097-971

7 January 2021

A large region (approximately equal to 95 kDa) of human factor VIII is dispensable for in vitro procoagulant activity

1 reference

https://api.crossref.org/works/10.1038%2FNBT1097-971

7 January 2021

Sequences in the coding region of clotting factor VIII act as dominant inhibitors of RNA accumulation and protein production.

1 reference

https://api.crossref.org/works/10.1038%2FNBT1097-971

7 January 2021

Sequences within the coding regions of clotting factor VIII and CFTR block transcriptional elongation

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https://api.crossref.org/works/10.1038%2FNBT1097-971

7 January 2021

Inactivation of human factor VIII by activated protein C. Cofactor activity of protein S and protective effect of von Willebrand factor

1 reference

https://api.crossref.org/works/10.1038%2FNBT1097-971

7 January 2021

Blood proteins from transgenic animal bioreactors

1 reference

https://api.crossref.org/works/10.1038%2FNBT1097-971

7 January 2021

Comparison of the whey acidic protein genra of the rat and mouse

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https://api.crossref.org/works/10.1038%2FNBT1097-971

7 January 2021

Characterization of the human factor VIII procoagulant protein with a heterologous precipitating antibody

1 reference

https://api.crossref.org/works/10.1038%2FNBT1097-971

7 January 2021

Proteolytic processing of human factor VIII. Correlation of specific cleavages by thrombin, factor Xa, and activated protein C with activation and inactivation of factor VIII coagulant activity

1 reference

https://api.crossref.org/works/10.1038%2FNBT1097-971

7 January 2021

Proteolytic requirements for thrombin activation of anti-hemophilic factor (factor VIII)

1 reference

https://api.crossref.org/works/10.1038%2FNBT1097-971

7 January 2021

Assay of factor VIII:C with a chromogenic substrate

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https://api.crossref.org/works/10.1038%2FNBT1097-971

7 January 2021

Proteolytic processing of human protein C in swine mammary gland

1 reference

https://api.crossref.org/works/10.1038%2FNBT1097-971

7 January 2021

Secretion of unprocessed human surfactant protein B in milk of transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FNBT1097-971

7 January 2021

Inefficient processing of human protein C in the mouse mammary gland

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https://api.crossref.org/works/10.1038%2FNBT1097-971

7 January 2021

Tissue-specific expression in the salivary glands of transgenic mice

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https://api.crossref.org/works/10.1038%2FNBT1097-971

7 January 2021

A milk protein gene promoter directs the expression of human tissue plasminogen activator cDNA to the mammary gland in transgenic mice

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https://api.crossref.org/works/10.1038%2FNBT1097-971

7 January 2021

A Mammary-Specific Promoter Directs Expression of Growth Hormone not only to the Mammary Gland, but also to Bergman Glia Cells in Transgenic Mice

1 reference

https://api.crossref.org/works/10.1038%2FNBT1097-971

7 January 2021

Expression of whey acidic protein (WAP) genes in tissues other than the mammary gland in normal and transgenic mice expressing mWAP/hGH fusion gene.

1 reference

https://api.crossref.org/works/10.1038%2FNBT1097-971

7 January 2021

High-level synthesis of a heterologous milk protein in the mammary glands of transgenic swine

1 reference

https://api.crossref.org/works/10.1038%2FNBT1097-971

7 January 2021

High-level expression of a heterologous protein in the milk of transgenic swine using the cDNA encoding human protein C

1 reference

https://api.crossref.org/works/10.1038%2FNBT1097-971

7 January 2021

Development of porcine ova that were centrifuged to permit visualization of pronuclei and nuclei

1 reference

https://api.crossref.org/works/10.1038%2FNBT1097-971

7 January 2021

Human factor VIII procoagulant protein. Monoclonal antibodies define precursor-product relationships and functional epitopes

1 reference

https://api.crossref.org/works/10.1038%2FNBT1097-971

7 January 2021

Identifiers

DOI

10.1038/NBT1097-971

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17 December 2017

Dimensions Publication ID

1021018372

0 references

1 reference

17 December 2017