Prolonged effect of a new O-glycoPEGylated FVIII (N8-GP) in a murine saphenous vein bleeding model. (Q45887979)

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2 March 2020

title

Prolonged effect of a new O-glycoPEGylated FVIII (N8-GP) in a murine saphenous vein bleeding model (English)

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4

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author name string

A E Pastoft

1

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M Ezban

2

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M Tranholm

3

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B Lauritzen

5

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publication date

4 June 2013

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2 March 2020

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volume

19

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issue

6

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page(s)

913-919

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Prophylaxis versus episodic treatment to prevent joint disease in boys with severe hemophilia

2 March 2020

cites work

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Secondary prophylaxis therapy: what are the benefits, limitations and unknowns?

21 January 2018

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Novel drugs to treat hemophilia

21 January 2018

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Hemophilia: new protein therapeutics

21 January 2018

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Safety and pharmacokinetics of a recombinant factor VIII with pegylated liposomes in severe hemophilia A.

21 January 2018

1 reference

Extending half-life in coagulation factors: where do we stand?

21 January 2018

1 reference

Purification and characterization of a new recombinant factor VIII (N8).

21 January 2018

1 reference

A novel B-domain O-glycoPEGylated FVIII (N8-GP) demonstrates full efficacy and prolonged effect in hemophilic mice models

21 January 2018

1 reference

A sensitive venous bleeding model in haemophilia A mice: effects of two recombinant FVIII products (N8 and Advate(®)).

21 January 2018

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Targeted disruption of the mouse factor VIII gene produces a model of haemophilia A.

21 January 2018

1 reference

rFVIIa and a new enhanced rFVIIa-analogue, NN1731, reduce bleeding in clopidogrel-treated and in thrombocytopenic rats

21 January 2018

1 reference

Improvements in factor concentrates

21 January 2018

1 reference

Surveillance of infectious complications associated with central venous access devices in children with haemophilia

21 January 2018

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The pharmacology of PEGylation: balancing PD with PK to generate novel therapeutics

21 January 2018

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The impact of PEGylation on biological therapies

21 January 2018

1 reference

Enhancement of the efficacy of therapeutic proteins by formulation with PEGylated liposomes; a case of FVIII, FVIIa and G-CSF.

21 January 2018

1 reference

Peg-asparaginase for acute lymphoblastic leukemia

21 January 2018

1 reference

Rational design of a fully active, long-acting PEGylated factor VIII for hemophilia A treatment

21 January 2018

1 reference

Prolonged half-life and preserved enzymatic properties of factor IX selectively PEGylated on native N-glycans in the activation peptide

21 January 2018

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Pharmacokinetics and pharmacodynamics of turoctocog alfa and N8-GP in haemophilia A dogs

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/HAE.12198

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2 March 2020

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