C-C motif chemokine receptor 9 positive macrophages activate hepatic stellate cells and promote liver fibrosis in mice. (Q45895187)

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25 February 2020

title

C-C motif chemokine receptor 9 positive macrophages activate hepatic stellate cells and promote liver fibrosis in mice (English)

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25 February 2020

1

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25 February 2020

Yohei Mikami

7

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25 February 2020

Takanori Kanai

10

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12

Toshifumi Hibi

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25 February 2020

author name string

Nobuhiro Nakamoto

2

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25 February 2020

Hirotoshi Ebinuma

3

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25 February 2020

Shingo Usui

4

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25 February 2020

Keita Saeki

5

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Atsuhiro Matsumoto

6

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Kazuo Sugiyama

8

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Kengo Tomita

9

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Hidetsugu Saito

11

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language of work or name

English

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publication date

31 May 2013

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volume

58

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issue

1

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page(s)

337-350

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Management of cirrhosis and ascites

25 February 2020

cites work

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Liver fibrosis -- from bench to bedside

21 January 2018

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21 January 2018

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Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver

21 January 2018

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Suppression of macrophage infiltration inhibits activation of hepatic stellate cells and liver fibrogenesis in rats

21 January 2018

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Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair

21 January 2018

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CCR2 promotes hepatic fibrosis in mice

21 January 2018

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Hepatic macrophage migration and differentiation critical for liver fibrosis is mediated by the chemokine receptor C-C motif chemokine receptor 8 in mice.

21 January 2018

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CX3CL1-CX3CR1 interaction prevents carbon tetrachloride-induced liver inflammation and fibrosis in mice

21 January 2018

1 reference

The fractalkine receptor CX₃CR1 protects against liver fibrosis by controlling differentiation and survival of infiltrating hepatic monocytes

21 January 2018

1 reference

Functional role of chemokines in liver disease models

21 January 2018

1 reference

TECK: a novel CC chemokine specifically expressed by thymic dendritic cells and potentially involved in T cell development

21 January 2018

1 reference

Human G protein-coupled receptor GPR-9-6/CC chemokine receptor 9 is selectively expressed on intestinal homing T lymphocytes, mucosal lymphocytes, and thymocytes and is required for thymus-expressed chemokine-mediated chemotaxis

21 January 2018

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CCR9 is a homing receptor for plasmacytoid dendritic cells to the small intestine

21 January 2018

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CCR9 expression defines tolerogenic plasmacytoid dendritic cells able to suppress acute graft-versus-host disease

21 January 2018

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Phenotype and effector function of CC chemokine receptor 9-expressing lymphocytes in small intestinal Crohn's disease.

21 January 2018

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Hepatic endothelial CCL25 mediates the recruitment of CCR9+ gut-homing lymphocytes to the liver in primary sclerosing cholangitis.

21 January 2018

1 reference

A role for CCR9 in T lymphocyte development and migration.

21 January 2018

1 reference

Migratory fate and differentiation of blood monocyte subsets

21 January 2018

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Critical role of tumor necrosis factor receptor 1, but not 2, in hepatic stellate cell proliferation, extracellular matrix remodeling, and liver fibrogenesis

21 January 2018

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Differentiation and function of mouse monocyte-derived dendritic cells in steady state and inflammation

21 January 2018

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Angiotensin-converting enzyme inhibition down-regulates the pro-atherogenic chemokine receptor 9 (CCR9)-chemokine ligand 25 (CCL25) axis

21 January 2018

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Monocytes/macrophages express chemokine receptor CCR9 in rheumatoid arthritis and CCL25 stimulates their differentiation

21 January 2018

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Immune stimulation of hepatic fibrogenesis by CD8 cells and attenuation by transgenic interleukin-10 from hepatocytes

21 January 2018

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IFN-gamma abrogates profibrogenic TGF-beta signaling in liver by targeting expression of inhibitory and receptor Smads

21 January 2018

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Cutting edge: Peyer's patch plasmacytoid dendritic cells (pDCs) produce low levels of type I interferons: possible role for IL-10, TGFbeta, and prostaglandin E2 in conditioning a unique mucosal pDC phenotype

21 January 2018

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Splenic stromal microenvironment negatively regulates virus-activated plasmacytoid dendritic cells through TGF-beta

21 January 2018

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Retinoic acid imprints gut-homing specificity on T cells

21 January 2018

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Ito cells are liver-resident antigen-presenting cells for activating T cell responses

21 January 2018

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Gut homing receptors on CD8 T cells are retinoic acid dependent and not maintained by liver dendritic or stellate cells.

21 January 2018

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Targeting leukocyte migration and adhesion in Crohn's disease and ulcerative colitis

21 January 2018

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Expression of CCR9 beta-chemokine receptor is modulated in thymocyte differentiation and is selectively maintained in CD8+ T cells from secondary lymphoid organs

21 January 2018

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Chemokine (C-C motif) receptors in fibrogenesis and hepatic regeneration following acute and chronic liver disease

21 January 2018

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7 January 2021

Hepatic recruitment of the inflammatory Gr1+monocyte subset upon liver injury promotes hepatic fibrosis

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7 January 2021

Inverse relationship between dendritic cell CCR9 expression and maturation state

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7 January 2021

CCR9+ macrophages are required for acute liver inflammation in mouse models of hepatitis

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7 January 2021

MyD88-dependent pathway accelerates the liver damage of Concanavalin A-induced hepatitis

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7 January 2021

Competition between colitogenic Th1 and Th17 cells contributes to the amelioration of colitis

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7 January 2021

Novel engineered targeted interferon-gamma blocks hepatic fibrogenesis in mice

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7 January 2021

Identifiers

DOI

10.1002/HEP.26351

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25 February 2020

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