Evaluation of exposure change of nonrenally eliminated drugs in patients with chronic kidney disease using physiologically based pharmacokinetic modeling and simulation. (Q45901623)

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scientific article published in January 2012

Language	Label	Description	Also known as
English	Evaluation of exposure change of nonrenally eliminated drugs in patients with chronic kidney disease using physiologically based pharmacokinetic modeling and simulation.	scientific article published in January 2012

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Evaluation of exposure change of nonrenally eliminated drugs in patients with chronic kidney disease using physiologically based pharmacokinetic modeling and simulation. (English)

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

chronic renal insufficiency

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

author name string

Ping Zhao

1

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Manuela de L T Vieira

2

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Joseph A Grillo

3

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Pengfei Song

4

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Ta-Chen Wu

5

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Jenny H Zheng

6

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Vikram Arya

7

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Eva Gil Berglund

8

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Arthur J Atkinson

9

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Yuichi Sugiyama

10

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

K Sandy Pang

11

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Kellie S Reynolds

12

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Darrell R Abernethy

13

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Lei Zhang

14

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Lawrence J Lesko

15

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Shiew-Mei Huang

16

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

publication date

1 January 2012

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

The Journal of Clinical Pharmacology

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Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

52

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

1 Suppl

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

91S-108S

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

Drug development perspective on pharmacokinetic studies of new drugs in patients with renal impairment.

1 reference

https://api.crossref.org/works/10.1177%2F0091270011415528

21 January 2018

Altered nonrenal drug clearance in ESRD.

1 reference

https://api.crossref.org/works/10.1177%2F0091270011415528

21 January 2018

Hepatic drug metabolism and transport in patients with kidney disease.

1 reference

https://api.crossref.org/works/10.1177%2F0091270011415528

21 January 2018

Hepatic clearance of drugs. I. Theoretical considerations of a "well-stirred" model and a "parallel tube" model. Influence of hepatic blood flow, plasma and blood cell binding, and the hepatocellular enzymatic activity on hepatic drug clearance

1 reference

https://api.crossref.org/works/10.1177%2F0091270011415528

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Pharmacokinetic modeling of the hepatobiliary transport mediated by cooperation of uptake and efflux transporters

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Application of physiologically based pharmacokinetic modeling and clearance concept to drugs showing transporter-mediated distribution and clearance in humans

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Applications of physiologically based pharmacokinetic (PBPK) modeling and simulation during regulatory review

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The effects of age and renal and hepatic impairment on the pharmacokinetics of sildenafil

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Comparative human pharmacokinetics and metabolism of single-dose oral and intravenous sildenafil

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The effects of steady-state erythromycin and azithromycin on the pharmacokinetics of sildenafil in healthy volunteers.

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Pharmacokinetics of sildenafil after single oral doses in healthy male subjects: absolute bioavailability, food effects and dose proportionality

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Pharmacokinetics of telithromycin: application to dosing in the treatment of community-acquired respiratory tract infections

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Pharmacokinetics and safety of the ketolide telithromycin in patients with renal impairment

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21 January 2018

Clinical pharmacokinetics of telithromycin, the first ketolide antibacterial

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21 January 2018

Identification of the cytochrome P450 enzymes involved in the N-demethylation of sildenafil

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21 January 2018

A framework for assessing inter-individual variability in pharmacokinetics using virtual human populations and integrating general knowledge of physical chemistry, biology, anatomy, physiology and genetics: A tale of 'bottom-up' vs 'top-down' recogn

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21 January 2018

Simulation and prediction of in vivo drug metabolism in human populations from in vitro data

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21 January 2018

Physiologically based mechanistic modelling to predict complex drug-drug interactions involving simultaneous competitive and time-dependent enzyme inhibition by parent compound and its metabolite in both liver and gut - the effect of diltiazem on th

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21 January 2018

Tissue distribution of basic drugs: accounting for enantiomeric, compound and regional differences amongst beta-blocking drugs in rat.

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21 January 2018

Physiologically based pharmacokinetic modeling 1: predicting the tissue distribution of moderate-to-strong bases.

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21 January 2018

Physiologically based pharmacokinetic modelling 2: predicting the tissue distribution of acids, very weak bases, neutrals and zwitterions

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21 January 2018

Prediction of intestinal first-pass drug metabolism

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21 January 2018

The Simcyp population-based ADME simulator

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21 January 2018

Cyclosporine markedly raises the plasma concentrations of repaglinide

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Effects of gemfibrozil and atorvastatin on the pharmacokinetics of repaglinide in relation to SLCO1B1 polymorphism

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21 January 2018

Pharmacokinetics and absolute oral bioavailability of an 800-mg oral dose of telithromycin in healthy young and elderly volunteers

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21 January 2018

Emerging evidence of the impact of kidney disease on drug metabolism and transport

1 reference

https://api.crossref.org/works/10.1177%2F0091270011415528

21 January 2018

Development of a physiology-based whole-body population model for assessing the influence of individual variability on the pharmacokinetics of drugs.

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21 January 2018

Physiologically-Based Pharmacokinetics in Drug Development and Regulatory Science

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21 January 2018

Prediction of the clearance of eleven drugs and associated variability in neonates, infants and children

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21 January 2018

A semi-mechanistic model to predict the effects of liver cirrhosis on drug clearance

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21 January 2018

Physiology-based simulations of a pathological condition: prediction of pharmacokinetics in patients with liver cirrhosis

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21 January 2018

Development and evaluation of a generic physiologically based pharmacokinetic model for children.

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21 January 2018

Identifiers

10.1177/0091270011415528

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 December 2017

http://europepmc.org/abstract/MED/22232759

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