Peroxisome proliferator-activated receptor-alpha activator fenofibrate prevents high-fat diet-induced renal lipotoxicity in spontaneously hypertensive rats. (Q45915450)

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scientific article published on 31 July 2009

Language	Label	Description	Also known as
English	Peroxisome proliferator-activated receptor-alpha activator fenofibrate prevents high-fat diet-induced renal lipotoxicity in spontaneously hypertensive rats.	scientific article published on 31 July 2009

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scholarly article

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/19644507

Peroxisome proliferator-activated receptor-alpha activator fenofibrate prevents high-fat diet-induced renal lipotoxicity in spontaneously hypertensive rats. (English)

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/19644507

author name string

Seok Joon Shin

1

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Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/19644507

Ji Hee Lim

2

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Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/19644507

Sungjin Chung

3

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Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/19644507

Dong-Ye Youn

4

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Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/19644507

Hyun Wha Chung

5

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Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/19644507

Hyung Wook Kim

6

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Europe PubMed Central

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http://europepmc.org/abstract/MED/19644507

Jeong-Hwa Lee

7

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Europe PubMed Central

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http://europepmc.org/abstract/MED/19644507

Yoon Sik Chang

8

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Europe PubMed Central

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http://europepmc.org/abstract/MED/19644507

Cheol Whee Park

9

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Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/19644507

publication date

31 July 2009

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http://europepmc.org/abstract/MED/19644507

Hypertension Research

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32

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835-845

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10

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http://europepmc.org/abstract/MED/19644507

https://scigraph.springernature.com/pub.10.1038/hr.2009.107

0 references

Obesity-related glomerulopathy: an emerging epidemic

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Obesity hypertension

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Non-esterified fatty acids and blood pressure elevation: a mechanism for hypertension in subjects with obesity/insulin resistance?

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Impaired nitric oxide synthase pathway in diabetes mellitus: role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase

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Cytosolic triglycerides and oxidative stress in central obesity: the missing link between excessive atherosclerosis, endothelial dysfunction, and beta-cell failure?

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Lipotoxicity: when tissues overeat

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Cellular mechanisms of insulin resistance

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Candesartan reduced advanced glycation end-products accumulation and diminished nitro-oxidative stress in type 2 diabetic KK/Ta mice

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Anti-Hypertensive Agents Inhibit In Vivo the Formation of Advanced Glycation End Products and Improve Renal Damage in a Type 2 Diabetic Nephropathy Rat Model

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In vivo imaging of oxidative stress in the kidney of diabetic mice and its normalization by angiotensin II type 1 receptor blocker

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Physiology of local renin-angiotensin systems.

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Possible involvement of the adipose tissue renin-angiotensin system in the pathophysiology of obesity and obesity-related disorders.

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Mechanisms of hypertension and kidney disease in obesity

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Peroxisome proliferator-activated receptor family and its relationship to renal complications of the metabolic syndrome

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Peroxisome proliferator-activated receptor alpha-isoform deficiency leads to progressive dyslipidemia with sexually dimorphic obesity and steatosis

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Docosahexaenoic acid, a peroxisome proliferator-activated receptor-alpha ligand, induces apoptosis in vascular smooth muscle cells by stimulation of p38 mitogen-activated protein kinase

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PPARalpha inhibits TGF-beta-induced beta5 integrin transcription in vascular smooth muscle cells by interacting with Smad4.

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PPARalpha activator effects on Ang II-induced vascular oxidative stress and inflammation

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Accelerated diabetic nephropathy in mice lacking the peroxisome proliferator-activated receptor alpha.

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PPARalpha agonist fenofibrate improves diabetic nephropathy in db/db mice.

1 reference

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21 January 2018

Fenofibrate prevents the development of angiotensin II-dependent hypertension in mice

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https://api.crossref.org/works/10.1038%2FHR.2009.107

21 January 2018

PPAR-alpha agonist fenofibrate induces renal CYP enzymes and reduces blood pressure and glomerular hypertrophy in Zucker diabetic fatty rats

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.107

21 January 2018

Endothelial dysfunction and the development of renal injury in spontaneously hypertensive rats fed a high-fat diet

1 reference

https://api.crossref.org/works/10.1038%2FHR.2009.107

21 January 2018

Diet-induced obesity delays cardiovascular recovery from stress in spontaneously hypertensive rats

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Clofibrate prevents the development of hypertension in Dahl salt-sensitive rats.

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Activation of the systemic and adipose renin-angiotensin system in rats with diet-induced obesity and hypertension

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Nephropathy in Zucker diabetic fat rat is associated with oxidative and nitrosative stress: prevention by chronic therapy with a peroxynitrite scavenger ebselen

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21 January 2018

Diet-induced obesity in C57BL/6J mice causes increased renal lipid accumulation and glomerulosclerosis via a sterol regulatory element-binding protein-1c-dependent pathway

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Inhibition of the renin-angiotensin system prevents free fatty acid-induced acute endothelial dysfunction in humans

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Antiobesity action of peripheral exenatide (exendin-4) in rodents: effects on food intake, body weight, metabolic status and side-effect measures

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Renal disease in patients with massive obesity

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Pathophysiological mechanisms of salt-dependent hypertension

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A novel PPARalpha agonist ameliorates insulin resistance in dogs fed a high-fat diet

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Effects of tempol on renal angiotensinogen production in Dahl salt-sensitive rats

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Hypoadiponectinemia

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Obesity-associated hypertension: new insights into mechanisms.

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Systemic administration of lipopolysaccharide upregulates angiotensin II expression in rat renal tubules: immunohistochemical and ELISA studies

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10.1038/HR.2009.107

1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/19644507

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1 reference

Europe PubMed Central

17 December 2017

http://europepmc.org/abstract/MED/19644507

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