Promise and problems in relating cellular senescence in vitro to aging in vivo. (Q45935125)

18 December 2017

title

Promise and problems in relating cellular senescence in vitro to aging in vivo. (English)

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18 December 2017

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Harry Rubin

1

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18 December 2017

publication date

1 May 2002

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18 December 2017

Archives of Gerontology and Geriatrics

published in

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18 December 2017

volume

34

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18 December 2017

issue

3

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18 December 2017

page(s)

275-286

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18 December 2017

Telomere length predicts replicative capacity of human fibroblasts

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Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice

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Enzyme patterns in cultured kidney cells

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Residual bodies and "aging" in cultured human glia cells. Effect of entrance into phase 3 and prolonged periods of confluence

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Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

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7 January 2021

Extension of life-span by introduction of telomerase into normal human cells

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7 January 2021

Evidence for cellular aging in long-term confluent cultures: heritable impairment of proliferation, accumulation of age pigments and their loss in neoplastic transformation

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Relationship between donor age and the replicative lifespan of human cells in culture: a reevaluation

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7 January 2021

Telomeres and senescence: ending the debate

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7 January 2021

The rate of telomere sequence loss in human leukocytes varies with age.

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7 January 2021

Telomerase activity, cell proliferation, and cancer

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7 January 2021

The serial cultivation of human diploid cell strains

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7 January 2021

THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

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7 January 2021

Telomeres shorten during ageing of human fibroblasts

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7 January 2021

Telomerase, cell immortality, and cancer

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7 January 2021

Telomerase activity in the regenerative basal layer of the epidermis inhuman skin and in immortal and carcinoma-derived skin keratinocytes

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7 January 2021

Wild-derived inbred mouse strains have short telomeres

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7 January 2021

Specific association of human telomerase activity with immortal cells and cancer

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7 January 2021

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

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7 January 2021

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Serial passage of embryonic human astrocytes in serum-free, hormone-supplemented medium

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7 January 2021

Essential role of mouse telomerase in highly proliferative organs

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7 January 2021

The life span of the cultured normal cell: Concepts derived from studies of human lymphoblasts

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7 January 2021

Effect of age on lymphocyte proliferation

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7 January 2021

Lack of replicative senescence in normal rodent glia

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7 January 2021

Developmental and tissue-specific regulation of mouse telomerase and telomere length

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7 January 2021

Morphologic changes accompanying senescence of cultured human diploid cells

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7 January 2021

Evidence for a relationship between longevity of mammalian species and life spans of normal fibroblasts in vitro and erythrocytes in vivo

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7 January 2021

Regulation of human fibroblast growth rate by both noncycling cell fraction transition probability is shown by growth in 5-bromodeoxyuridine followed by Hoechst 33258 flow cytometry

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7 January 2021

Heritable, population-wide damage to cells as the driving force of neoplastic transformation

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7 January 2021

Cellular aging, destabilization, and cancer

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7 January 2021

Cell aging in vivo and in vitro

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7 January 2021

Telomerase and cellular lifespan: ending the debate?

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7 January 2021

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

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7 January 2021

The role of selection in progressive neoplastic transformation

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7 January 2021

Variation in the life-span of clones derived from human diploid cell strains

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7 January 2021

Comparison of doubling numbers attained by cultured animal cells with life span of species

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7 January 2021

Mouse embryonic stem cells exhibit indefinite proliferative potential.

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7 January 2021

Extensive telomere repeat arrays in mouse are hypervariable

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7 January 2021

A survey of telomerase activity in human cancer

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7 January 2021

Lack of replicative senescence in cultured rat oligodendrocyte precursor cells

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7 January 2021

The molecular genetics of cellular oncogenes

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7 January 2021

Telomerase expression in chickens: constitutive activity in somatic tissues and down-regulation in culture

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7 January 2021

New link in a web of human genes

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7 January 2021

Telomeres in the mouse have large inter-chromosomal variations in the number of T2AG3 repeats

1 reference

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7 January 2021

10.1016/S0167-4943(01)00221-7

Identifiers

DOI

1 reference

18 December 2017

release_bll5bcymc5ebvlzwpsx2ua2dpm

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/bll5bcymc5ebvlzwpsx2ua2dpm

24 November 2022

mapped directly with Wikidata item

PubMed ID

14764330

1 reference

18 December 2017