Optimal subsite occupancy and design of a selective inhibitor of urokinase. (Q45940894)

18 December 2017

title

Optimal subsite occupancy and design of a selective inhibitor of urokinase. (English)

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18 December 2017

author name string

Ke SH

1

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18 December 2017

Coombs GS

2

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18 December 2017

Tachias K

3

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18 December 2017

Corey DR

4

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18 December 2017

Madison EL

5

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18 December 2017

language of work or name

English

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publication date

1 August 1997

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18 December 2017

Journal of Biological Chemistry

number of pages

7

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based on heuristic

inferred from page(s)

published in

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18 December 2017

volume

272

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18 December 2017

issue

33

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18 December 2017

page(s)

20456-20462

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18 December 2017

The crystal structure of the catalytic domain of human urokinase-type plasminogen activator

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Distinguishing the specificities of closely related proteases. Role of P3 in substrate and inhibitor discrimination between tissue-type plasminogen activator and urokinase.

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Probing structure-function relationships of tissue-type plasminogen activator by oligonucleotide-mediated site-specific mutagenesis

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The refined 1.9-Å X-ray crystal structure of d-Phe-Pro-Arg chloromethylketone-inhibited human α-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships

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21 January 2018

Identifiers

DOI

10.1074/JBC.272.33.20456

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18 December 2017

PubMed ID

9252355

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18 December 2017