DNA methylation inhibits p53-mediated survivin repression. (Q45976995)

18 December 2017

title

DNA methylation inhibits p53-mediated survivin repression. (English)

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18 December 2017

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N H Nabilsi

1

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18 December 2017

R R Broaddus

series ordinal

2

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18 December 2017

D S Loose

series ordinal

3

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18 December 2017

language of work or name

English

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publication date

13 April 2009

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18 December 2017

published in

Oncogene

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18 December 2017

volume

28

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18 December 2017

issue

19

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18 December 2017

page(s)

2046-2050

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18 December 2017

https://scigraph.springernature.com/pub.10.1038/onc.2009.62

exact match

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cites work

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Induction of apoptosis and inhibition of cell proliferation by survivin gene targeting

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CpG methylation as a mechanism for the regulation of E2F activity

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COX-2 and survivin are overexpressed and positively correlated in endometrial carcinoma

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Human maintenance DNA (cytosine-5)-methyltransferase and p53 modulate expression of p53-repressed promoters

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Survivin, a cancer target with an emerging role in normal adult tissues

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The high frequency of de novo promoter methylation in synchronous primary endometrial and ovarian carcinomas.

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DNA demethylase is expressed in ovarian cancers and the expression correlates with demethylation of CpG sites in the promoter region of c-erbB-2 and survivin genes

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Transcriptional repression of the anti-apoptotic survivin gene by wild type p53.

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DNA methylation profiling of myelodysplastic syndrome hematopoietic progenitor cells during in vitro lineage-specific differentiation.

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Correlation of survivin mRNA detection with histologic diagnosis in normal endometrium and endometrial carcinoma

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Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway

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Dual role of DNA methylation inside and outside of CTCF-binding regions in the transcriptional regulation of the telomerase hTERT gene

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CTCF binds the proximal exonic region of hTERT and inhibits its transcription

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Survivin expression correlates with clinical stage, histological grade, invasive behavior and survival rate in endometrial carcinoma

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Hypomethylation-linked activation of PAX2 mediates tamoxifen-stimulated endometrial carcinogenesis

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Deregulation of the HOXA10 homeobox gene in endometrial carcinoma: role in epithelial-mesenchymal transition.

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Identifiers

DOI

10.1038/ONC.2009.62

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18 December 2017

Dimensions Publication ID

1013534679

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18 December 2017