Rottlerin inhibits (Na+, K+)-ATPase activity in brain tissue and alters D-aspartate dependent redistribution of glutamate transporter GLAST in cultured astrocytes. (Q45983261)

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scientific article published on 3 June 2009

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English	Rottlerin inhibits (Na+, K+)-ATPase activity in brain tissue and alters D-aspartate dependent redistribution of glutamate transporter GLAST in cultured astrocytes.	scientific article published on 3 June 2009

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scholarly article

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19495968

Rottlerin inhibits (Na+, K+)-ATPase activity in brain tissue and alters D-aspartate dependent redistribution of glutamate transporter GLAST in cultured astrocytes. (English)

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19495968

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Caroline D. Rae

3

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18 December 2017

http://europepmc.org/abstract/MED/19495968

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Paul L Else

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18 December 2017

http://europepmc.org/abstract/MED/19495968

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Khoa T D Nguyen

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18 December 2017

http://europepmc.org/abstract/MED/19495968

Jae-Won Shin

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18 December 2017

http://europepmc.org/abstract/MED/19495968

Ellas K Nanitsos

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18 December 2017

http://europepmc.org/abstract/MED/19495968

Gabriela B Acosta

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18 December 2017

http://europepmc.org/abstract/MED/19495968

David V Pow

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18 December 2017

http://europepmc.org/abstract/MED/19495968

Vlado Buljan

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18 December 2017

http://europepmc.org/abstract/MED/19495968

Maxwell R Bennett

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18 December 2017

http://europepmc.org/abstract/MED/19495968

Vladimir J Balcar

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http://europepmc.org/abstract/MED/19495968

publication date

3 June 2009

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18 December 2017

http://europepmc.org/abstract/MED/19495968

Neurochemical Research

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18 December 2017

http://europepmc.org/abstract/MED/19495968

34

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http://europepmc.org/abstract/MED/19495968

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http://europepmc.org/abstract/MED/19495968

1767-1774

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18 December 2017

http://europepmc.org/abstract/MED/19495968

Relationship between body size, Na+-K+-ATPase activity, and membrane lipid composition in mammal and bird kidney

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https://api.crossref.org/works/10.1007%2FS11064-009-9996-6

21 January 2018

A pharmacological review of competitive inhibitors and substrates of high-affinity, sodium-dependent glutamate transport in the central nervous system

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https://pubmed.ncbi.nlm.nih.gov/19495968

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Molecular pharmacology of the Na+-dependent transport of acidic amino acids in the mammalian central nervous system

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https://pubmed.ncbi.nlm.nih.gov/19495968

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Antagonists of protein kinase C inhibit rat retinal glutamate transport activity in situ.

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https://pubmed.ncbi.nlm.nih.gov/19495968

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Carnosic acid and promotion of monocytic differentiation of HL60-G cells initiated by other agents

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https://pubmed.ncbi.nlm.nih.gov/19495968

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Inhibition of calmodulin-stimulated (Ca2+ + Mg2+)-ATPase activity by dimethyl sulfoxide

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https://pubmed.ncbi.nlm.nih.gov/19495968

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Glial glutamate transporters mediate a functional metabolic crosstalk between neurons and astrocytes in the mouse developing cortex

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https://pubmed.ncbi.nlm.nih.gov/19495968

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Strategies for studies of neurotoxic mechanisms involving deficient transport of L-glutamate: antisense knockout in rat brain in vivo and changes in the neurotransmitter metabolism following inhibition of glutamate transport in guinea pig brain slic

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Glutamate uptake

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https://pubmed.ncbi.nlm.nih.gov/19495968

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Structural selectivity and molecular nature of L-glutamate transport in cultured human fibroblasts.

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https://pubmed.ncbi.nlm.nih.gov/19495968

12 December 2020

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Stoichiometric coupling of brain glucose metabolism and glutamatergic neuronal activity

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https://pubmed.ncbi.nlm.nih.gov/19495968

12 December 2020

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Rottlerin, a PKC isozyme-selective inhibitor, affects signaling events and cytokine production in human monocytes

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https://pubmed.ncbi.nlm.nih.gov/19495968

12 December 2020

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Neuronal-induced and glutamate-dependent activation of glial glutamate transporter function

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https://pubmed.ncbi.nlm.nih.gov/19495968

12 December 2020

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Dimethyl sulfoxide: a possible effect on the interconversion of phosphorylated forms of Na+,K(+)-ATPase

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https://pubmed.ncbi.nlm.nih.gov/19495968

12 December 2020

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Effects of glutamate transport substrates and glutamate receptor ligands on the activity of Na-/K(+)-ATPase in brain tissue in vitro

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https://pubmed.ncbi.nlm.nih.gov/19495968

12 December 2020

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Inhibitors of glutamate transport modulate distinct patterns in brain metabolism

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https://pubmed.ncbi.nlm.nih.gov/19495968

12 December 2020

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Specificity and mechanism of action of some commonly used protein kinase inhibitors

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https://pubmed.ncbi.nlm.nih.gov/19495968

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Transporters for L-glutamate: an update on their molecular pharmacology and pathological involvement

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https://pubmed.ncbi.nlm.nih.gov/19495968

12 December 2020

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Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells.

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https://pubmed.ncbi.nlm.nih.gov/19495968

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Glutamate induces rapid upregulation of astrocyte glutamate transport and cell-surface expression of GLAST.

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https://pubmed.ncbi.nlm.nih.gov/19495968

12 December 2020

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Regulated trafficking of neurotransmitter transporters: common notes but different melodies

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https://pubmed.ncbi.nlm.nih.gov/19495968

12 December 2020

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Rottlerin, an inhibitor of protein kinase Cdelta (PKCdelta), inhibits astrocytic glutamate transport activity and reduces GLAST immunoreactivity by a mechanism that appears to be PKCdelta-independent

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https://pubmed.ncbi.nlm.nih.gov/19495968

12 December 2020

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Glutamate uptake stimulates Na+,K+-ATPase activity in astrocytes via activation of a distinct subunit highly sensitive to ouabain.

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https://pubmed.ncbi.nlm.nih.gov/19495968

12 December 2020

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Distribution of glutamate transporter GLAST in membranes of cultured astrocytes in the presence of glutamate transport substrates and ATP.

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https://pubmed.ncbi.nlm.nih.gov/19495968

12 December 2020

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The role of glutamate transporters in neurodegenerative diseases and potential opportunities for intervention

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https://pubmed.ncbi.nlm.nih.gov/19495968

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Rottlerin is a mitochondrial uncoupler that decreases cellular ATP levels and indirectly blocks protein kinase Cdelta tyrosine phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19495968

12 December 2020

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Inhibition of cyclin-dependent kinases by purine analogues

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https://pubmed.ncbi.nlm.nih.gov/19495968

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Differential regulation of GLAST immunoreactivity and activity by protein kinase C: evidence for modification of amino and carboxyl termini

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https://pubmed.ncbi.nlm.nih.gov/19495968

12 December 2020

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Effects of L-glutamate transport inhibition by a conformationally restricted glutamate analogue (2S,1'S,2'R)-2-(carboxycyclopropyl)glycine (L-CCG III) on metabolism in brain tissue in vitro analysed by NMR spectroscopy

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https://pubmed.ncbi.nlm.nih.gov/19495968

12 December 2020

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Cell volume and K+ transport during differentiation of mouse erythroleukemia cells

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https://pubmed.ncbi.nlm.nih.gov/19495968

12 December 2020

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Molecular pharmacology and physiology of glutamate transporters in the central nervous system

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https://pubmed.ncbi.nlm.nih.gov/19495968

12 December 2020

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Pro-apoptotic protein kinase C delta is associated with intranuclear inclusions in a transgenic model of Huntington's disease.

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https://pubmed.ncbi.nlm.nih.gov/19495968

12 December 2020

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Similar perisynaptic glial localization for the Na+,K+-ATPase alpha 2 subunit and the glutamate transporters GLAST and GLT-1 in the rat somatosensory cortex

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https://pubmed.ncbi.nlm.nih.gov/19495968

12 December 2020

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The structural specificity of the high affinity uptake of L-glutamate and L-aspartate by rat brain slices

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https://pubmed.ncbi.nlm.nih.gov/19495968

12 December 2020

based on heuristic

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Identifiers

10.1007/S11064-009-9996-6

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19495968

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/19495968

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