Inactivation of Ras by p120GAP via focal adhesion kinase dephosphorylation mediates RGMa-induced growth cone collapse. (Q46003290)

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28 January 2020

title

Inactivation of Ras by p120GAP via focal adhesion kinase dephosphorylation mediates RGMa-induced growth cone collapse (English)

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2

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author name string

Mitsuharu Endo

series ordinal

1

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language of work or name

English

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publication date

1 May 2009

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28 January 2020

published in

Journal of Neuroscience

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volume

29

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28 January 2020

issue

20

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page(s)

6649-6662

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Concerted activity of tyrosine phosphatase SHP-2 and focal adhesion kinase in regulation of cell motility

28 January 2020

cites work

1 reference

12 December 2020

p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation

1 reference

12 December 2020

Downregulation of the Ras-mitogen-activated protein kinase pathway by the EphB2 receptor tyrosine kinase is required for ephrin-induced neurite retraction

1 reference

12 December 2020

SH2 domains, interaction modules and cellular wiring

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12 December 2020

RGM is a repulsive guidance molecule for retinal axons

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12 December 2020

Transgenic RNA interference in ES cell-derived embryos recapitulates a genetic null phenotype.

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12 December 2020

Activation of the Ras superfamily of small GTPases. Workshop on exchange factors

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12 December 2020

Ras GTPase-activating protein binds to Akt and is required for its activation

1 reference

12 December 2020

Overexpression of FAK promotes Ras activity through the formation of a FAK/p120RasGAP complex in malignant astrocytoma cells

1 reference

12 December 2020

The repulsive guidance molecule RGMa is involved in the formation of afferent connections in the dentate gyrus.

1 reference

12 December 2020

Association between GTPase activators for Rho and Ras families.

1 reference

12 December 2020

Neogenin mediates the action of repulsive guidance molecule

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12 December 2020

The Semaphorin 4D receptor Plexin-B1 is a GTPase activating protein for R-Ras

1 reference

12 December 2020

Focal adhesion kinase in netrin-1 signaling

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12 December 2020

Netrins and neogenin promote myotube formation

1 reference

12 December 2020

Annexin A6 stimulates the membrane recruitment of p120GAP to modulate Ras and Raf-1 activity

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12 December 2020

Ras regulates neuronal polarity via the PI3-kinase/Akt/GSK-3beta/CRMP-2 pathway

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12 December 2020

Eph receptors inactivate R-Ras through different mechanisms to achieve cell repulsion

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12 December 2020

RGMa inhibition promotes axonal growth and recovery after spinal cord injury.

1 reference

12 December 2020

Role of protein-tyrosine phosphatase SHP2 in focal adhesion kinase down-regulation during neutrophil cathepsin G-induced cardiomyocytes anoikis

1 reference

12 December 2020

R-Ras controls axon specification upstream of glycogen synthase kinase-3beta through integrin-linked kinase

1 reference

12 December 2020

Molecular mechanisms involved in Ras inactivation: the annexin A6-p120GAP complex.

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12 December 2020

Neogenin-RGMa signaling at the growth cone is bone morphogenetic protein-independent and involves RhoA, ROCK, and PKC

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12 December 2020

Myosin IIA is required for neurite outgrowth inhibition produced by repulsive guidance molecule

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12 December 2020

Robust neuronal symmetry breaking by Ras-triggered local positive feedback

1 reference

12 December 2020

Regulation of p21ras activity

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12 December 2020

Tyrosine phosphorylation of netrin receptors in netrin-1 signaling

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12 December 2020

RasGAPs: a crucial regulator of extracellular stimuli for homeostasis of cellular functions.

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12 December 2020

Inhibition of branching and spine maturation by repulsive guidance molecule in cultured cortical neurons.

1 reference

12 December 2020

Regulation of axonal elongation and pathfinding from the entorhinal cortex to the dentate gyrus in the hippocampus by the chemokine stromal cell-derived factor 1 alpha

1 reference

12 December 2020

Protein-tyrosine kinases regulate the phosphorylation, protein interactions, subcellular distribution, and activity of p21ras GTPase-activating protein

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12 December 2020

A C-terminal domain of GAP is sufficient to stimulate ras p21 GTPase activity.

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12 December 2020

A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants

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12 December 2020

R-ras interacts with rasGAP, neurofibromin and c-raf but does not regulate cell growth or differentiation

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12 December 2020

Proteins regulating Ras and its relatives

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12 December 2020

The N-terminal region of GAP regulates cytoskeletal structure and cell adhesion

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12 December 2020

The Ca2+-dependent lipid binding domain of P120GAP mediates protein-protein interactions with Ca2+-dependent membrane-binding proteins. Evidence for a direct interaction between annexin VI and P120GAP

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12 December 2020

The Regulation of the Expression, Phosphorylation, and Protein Associations of pp125FAKduring Rat Brain Development

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12 December 2020

Focal adhesion kinase tyrosine-861 is a major site of phosphorylation by Src.

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12 December 2020

R-Ras can activate the phosphoinositide 3-kinase but not the MAP kinase arm of the Ras effector pathways.

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12 December 2020

Activation of R-Ras GTPase by GTPase-activating proteins for Ras, Gap1(m), and p120GAP.

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12 December 2020

10.1523/JNEUROSCI.0927-09.2009

Identifiers

DOI

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28 January 2020

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PubMed publication ID

19458235

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