The minisatellite in the diabetes susceptibility locus IDDM2 regulates insulin transcription. (Q46033146)

18 December 2017

title

The minisatellite in the diabetes susceptibility locus IDDM2 regulates insulin transcription. (English)

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18 December 2017

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G C Kennedy

1

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18 December 2017

M S German

series ordinal

2

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18 December 2017

W J Rutter

series ordinal

3

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18 December 2017

language of work or name

English

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publication date

1 March 1995

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18 December 2017

published in

Nature Genetics

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18 December 2017

volume

9

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18 December 2017

page(s)

293-298

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18 December 2017

issue

3

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18 December 2017

https://scigraph.springernature.com/pub.10.1038/ng0395-293

exact match

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cites work

Triplet repeat genes raise questions

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Analysis of a 1963-bp polymorphic region flanking the human insulin gene.

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Insulin-IGF2 region on chromosome 11p encodes a gene implicated in HLA-DR4-dependent diabetes susceptibility

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A genome-wide search for human type 1 diabetes susceptibility genes

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HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

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Characterization of a cDNA encoding the insulin gene GAGA-binding factor, Pur-I.

21 January 2018

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Minisatellite binding protein Msbp-1 is a sequence-specific single-stranded DNA-binding protein

21 January 2018

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7 January 2021

Two hypervariable minisatellite DNA binding proteins

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Members of therel/NF-χB family of transcriptional regulatory proteins bind theHRAS1minisatellite DNA sequence

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Hypervariable minisatellite DNA is a hotspot for homologous recombination in human cells

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Triplet repeats on the rise

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The highly polymorphic region near the human insulin gene is composed of simple tandemly repeating sequences.

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7 January 2021

Polymorphic DNA region adjacent to the 5' end of the human insulin gene

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Cell-specific expression controlled by the 5′-flanking region of insulin and chymotrypsin genes

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A Polymorphic Locus Near the Human Insulin Gene Is Associated with Insulin-dependent Diabetes Melliitus

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7 January 2021

Insulin gene region-encoded susceptibility to type 1 diabetes is not restricted to HLA-DR4-positive individuals

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7 January 2021

Localization of a type I diabetes susceptibility locus to the variable tandem repeat region flanking the insulin gene

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7 January 2021

Susceptibility to insulin dependent diabetes mellitus maps to a 4.1 kb segment of DNA spanning the insulin gene and associated VNTR.

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7 January 2021

HLA-D region β-chain DNA endonuclease fragments differ between HLA-DR identical healthy and insulin-dependent diabetic individuals

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7 January 2021

Oligonucleotide probes for HLA-DQA and DQB genes define susceptibility to type 1 (insulin-dependent) diabetes mellitus.

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7 January 2021

A diabetes-susceptible HLA haplotype is best defined by a combination of HLA-DR and -DQ alleles

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7 January 2021

Primary association of HLA-DQw8 with type I diabetes in DR4 patients

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Pur-1, a zinc-finger protein that binds to purine-rich sequences, transactivates an insulin promoter in heterologous cells

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7 January 2021

Molecular cloning of an enhancer binding protein: isolation by screening of an expression library with a recognition site DNA

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7 January 2021

Preferential nucleosome assembly at DNA triplet repeats from the myotonic dystrophy gene

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7 January 2021

The human insulin gene linked polymorphic region exhibits an altered DNA structure

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7 January 2021

A consensus repeat sequence from the human insulin gene linked polymorphic region adopts multiple quadriplex DNA structures in vitro

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7 January 2021

The human insulin gene-linked polymorphic region adopts a G-quartet structure in chromatin assembled in vitro

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7 January 2021

Genetic dissection of complex traits

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7 January 2021

Identifiers

DOI

10.1038/NG0395-293

1 reference

18 December 2017

PubMed ID

7773292

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18 December 2017