Product inhibition in the radical S-adenosylmethionine family (Q46071153)

19 December 2017

title

Product inhibition in the radical S-adenosylmethionine family (English)

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19 December 2017

author

Peter L Roach

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author name string

Martin R Challand

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Tillman Ziegert

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Paul Douglas

3

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Robert J Wood

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Marco Kriek

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Nicholas M Shaw

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language of work or name

English

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publication date

26 March 2009

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19 December 2017

published in

FEBS Letters

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volume

583

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issue

8

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page(s)

1358-1362

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Radical SAM, a novel protein superfamily linking unresolved steps in familiar biosynthetic pathways with radical mechanisms: functional characterization using new analysis and information visualization methods

cites work

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An anchoring role for FeS clusters: chelation of the amino acid moiety of S-adenosylmethionine to the unique iron site of the [4Fe-4S] cluster of pyruvate formate-lyase activating enzyme

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Coordination and Mechanism of Reversible Cleavage of S-Adenosylmethionine by the [4Fe-4S] Center in Lysine 2,3-Aminomutase

21 January 2018

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Direct H atom abstraction from spore photoproduct C-6 initiates DNA repair in the reaction catalyzed by spore photoproduct lyase: evidence for a reversibly generated adenosyl radical intermediate

21 January 2018

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Biotin Synthase from Escherichiacoli, an Investigation of the Low Molecular Weight and Protein Components Required for Activity inVitro

21 January 2018

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Assembly of the covalent linkage between lipoic acid and its cognate enzymes.

21 January 2018

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Lipoyl synthase requires two equivalents of S-adenosyl-L-methionine to synthesize one equivalent of lipoic acid.

21 January 2018

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Spectroscopic changes during a single turnover of biotin synthase: destruction of a [2Fe-2S] cluster accompanies sulfur insertion

21 January 2018

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Biotin synthase is catalytic in vivo, but catalysis engenders destruction of the protein

21 January 2018

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A nucleosidase required for in vivo function of the S-adenosyl-L-methionine radical enzyme, biotin synthase

21 January 2018

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The PLP-dependent biotin synthase from Escherichia coli: mechanistic studies

21 January 2018

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Escherichia coli biotin synthase produces selenobiotin. Further evidence of the involvement of the [2Fe-2S]2+ cluster in the sulfur insertion step

21 January 2018

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21 January 2018

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Thiazole synthase from Escherichia coli: an investigation of the substrates and purified proteins required for activity in vitro.

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The activity of a thermostable lipoyl synthase from Sulfolobus solfataricus with a synthetic octanoyl substrate

21 January 2018

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S-adenosylmethionine as an oxidant: the radical SAM superfamily

21 January 2018

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Mechanistic investigations of lipoic acid biosynthesis in Escherichia coli: both sulfur atoms in lipoic acid are contributed by the same lipoyl synthase polypeptide

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21 January 2018

Identifiers

DOI

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19 December 2017

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19 December 2017