Conformational changes of the multispecific transporter organic anion transporter 1 (OAT1/SLC22A6) suggests a molecular mechanism for initial stages of drug and metabolite transport. (Q46071440)

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English	Conformational changes of the multispecific transporter organic anion transporter 1 (OAT1/SLC22A6) suggests a molecular mechanism for initial stages of drug and metabolite transport.	scientific article

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28 January 2020

Conformational changes of the multispecific transporter organic anion transporter 1 (OAT1/SLC22A6) suggests a molecular mechanism for initial stages of drug and metabolite transport (English)

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28 January 2020

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28 January 2020

Valentina L Kouznetsova

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Valentina L Kouznetsova

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Sanjay K Nigam

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Dmytro Kovalskyy

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28 January 2020

Oleksii Balinskyi

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28 January 2020

Yuriy Sharikov

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28 January 2020

Vibha Bhatnagar

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1 November 2011

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Cell Biochemistry and Biophysics

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28 January 2020

Lactose permease as a paradigm for membrane transport proteins (Review).

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21 January 2018

Structure and mechanism of the lactose permease of Escherichia coli

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High-yield expression and functional analysis of Escherichia coli glycerol-3-phosphate transporter.

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21 January 2018

Nucleotide sequence and transcriptional startpoint of the glpT gene of Escherichia coli: extensive sequence homology of the glycerol-3-phosphate transport protein with components of the hexose-6-phosphate transport system

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21 January 2018

The 12-transmembrane helix transporters

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21 January 2018

Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli

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21 January 2018

Mammalian integral membrane receptors are homologous to facilitators and antiporters of yeast, fungi, and eubacteria

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21 January 2018

Molecular cloning and characterization of NKT, a gene product related to the organic cation transporter family that is almost exclusively expressed in the kidney

1 reference

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21 January 2018

Handling of cysteine S-conjugates of methylmercury in MDCK cells expressing human OAT1.

1 reference

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21 January 2018

Decreased renal organic anion secretion and plasma accumulation of endogenous organic anions in OAT1 knock-out mice.

1 reference

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21 January 2018

Overlapping in vitro and in vivo specificities of the organic anion transporters OAT1 and OAT3 for loop and thiazide diuretics.

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21 January 2018

Expression and function of Oat1 and Oat3 in rat kidney exposed to mercuric chloride.

1 reference

https://api.crossref.org/works/10.1007%2FS12013-011-9191-7

21 January 2018

Organic anion transporter (Slc22a) family members as mediators of toxicity

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21 January 2018

Characterization of ochratoxin A transport by human organic anion transporters

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21 January 2018

Transport of organic anions across the basolateral membrane of proximal tubule cells

1 reference

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21 January 2018

Low doses of ochratoxin A upregulate the protein expression of organic anion transporters Oat1, Oat2, Oat3 and Oat5 in rat kidney cortex

1 reference

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21 January 2018

Multi-level analysis of organic anion transporters 1, 3, and 6 reveals major differences in structural determinants of antiviral discrimination

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21 January 2018

X-ray structure of EmrE supports dual topology model

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21 January 2018

Eukaryotic major facilitator superfamily transporter modeling based on the prokaryotic GlpT crystal structure.

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21 January 2018

A three-dimensional model of human organic anion transporter 1: aromatic amino acids required for substrate transport

1 reference

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21 January 2018

Modeling of glycerol-3-phosphate transporter suggests a potential 'tilt' mechanism involved in its function

1 reference

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21 January 2018

Hidden Markov models-based system (HMMSPECTR) for detecting structural homologies on the basis of sequential information

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21 January 2018

Functional analysis of polymorphisms in the organic anion transporter, SLC22A6 (OAT1).

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21 January 2018

GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

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21 January 2018

Validation of the 53A6 GROMOS force field

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21 January 2018

A biomolecular force field based on the free enthalpy of hydration and solvation: the GROMOS force-field parameter sets 53A5 and 53A6

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21 January 2018

Dynamite extended: two new services to simplify protein dynamic analysis.

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21 January 2018

Molecular cloning and characterization of two novel human renal organic anion transporters (hOAT1 and hOAT3)

1 reference

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21 January 2018

Selective amplification of protein-coding regions of large sets of genes using statistically designed primer sets

1 reference

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21 January 2018

Novel aspects of renal organic anion transporters

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21 January 2018

The molecular pharmacology of organic anion transporters: from DNA to FDA?

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21 January 2018

Structure, function, and regulation of renal organic anion transporters

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21 January 2018

The role of organic ion transporters in drug disposition: an update

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21 January 2018

Molecular insights into the structure-function relationship of organic anion transporters OATs

1 reference

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21 January 2018

Interaction of organic cations with organic anion transporters

1 reference

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21 January 2018

Toward a systems level understanding of organic anion and other multispecific drug transporters: a remote sensing and signaling hypothesis

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21 January 2018

Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members

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21 January 2018

Identifiers

10.1007/S12013-011-9191-7

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28 January 2020

PubMed publication ID

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Europe PubMed Central

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28 January 2020

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