Reproducible association with type 1 diabetes in the extended class I region of the major histocompatibility complex (Q46084074)

19 December 2017

title

Reproducible association with type 1 diabetes in the extended class I region of the major histocompatibility complex (English)

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19 December 2017

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I Kockum

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Flemming Pociot

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F Pociot

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Dag Undlien

10

object named as

D E Undlien

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19 December 2017

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E Thorsby

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A Cambon-Thomsen

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author name string

M K Viken

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A Blomhoff

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M Olsson

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H E Akselsen

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J Nerup

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B A Lie

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19 December 2017

publication date

19 March 2009

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19 December 2017

published in

Genes and Immunity

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19 December 2017

volume

10

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issue

4

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page(s)

323-333

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Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

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The predisposition to type 1 diabetes linked to the human leukocyte antigen complex includes at least one non-class II gene

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"Extended" A1, B8, DR3 haplotype shows remarkable linkage disequilibrium but is similar to nonextended haplotypes in terms of diabetes risk

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A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC.

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HLA complex genes in type 1 diabetes and other autoimmune diseases. Which genes are involved?

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Inheritable variable sizes of DNA stretches in the human MHC: conserved extended haplotypes and their fragments or blocks

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Linkage disequilibrium and haplotype blocks in the MHC vary in an HLA haplotype specific manner assessed mainly by DRB1*03 and DRB1*04 haplotypes.

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Association analysis in type 1 diabetes of the PRSS16 gene encoding a thymus-specific serine protease

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Analysis of single nucleotide polymorphisms identifies major type 1A diabetes locus telomeric of the major histocompatibility complex

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Conditional analyses on the T1DGC MHC dataset: novel associations with type 1 diabetes around HLA-G and confirmation of HLA-B

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Non-class II HLA gene associated with type 1 diabetes maps to the 240-kb region near HLA-B

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Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A

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Human leukocyte antigen class I B and C loci contribute to Type 1 Diabetes (T1D) susceptibility and age at T1D onset

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The cluster of BTN genes in the extended major histocompatibility complex

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Problems of reporting genetic associations with complex outcomes

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FCGR3B copy number variation is associated with susceptibility to systemic, but not organ-specific, autoimmunity

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Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans

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7 January 2021

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7 January 2021

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7 January 2021

Identifiers

DOI

10.1038/GENE.2009.13

1 reference

19 December 2017

1 reference

19 December 2017