Association of GCKR rs780094, alone or in combination with GCK rs1799884, with type 2 diabetes and related traits in a Han Chinese population (Q46110246)

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scientific article published on 25 February 2009

Language	Label	Description	Also known as
English	Association of GCKR rs780094, alone or in combination with GCK rs1799884, with type 2 diabetes and related traits in a Han Chinese population	scientific article published on 25 February 2009

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scholarly article

1 reference

Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19241058

Association of GCKR rs780094, alone or in combination with GCK rs1799884, with type 2 diabetes and related traits in a Han Chinese population (English)

1 reference

Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19241058

type 2 diabetes

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8

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http://europepmc.org/abstract/MED/19241058

4

object named as

R J F Loos

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Europe PubMed Central

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object named as

F B Hu

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http://europepmc.org/abstract/MED/19241058

author name string

Q Qi

1

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Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19241058

Y Wu

2

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Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19241058

H Li

3

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Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19241058

L Sun

6

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Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19241058

L Lu

7

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Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19241058

C Liu

9

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Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19241058

H Wu

10

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Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19241058

L Chen

11

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Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19241058

Z Yu

12

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Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19241058

X Lin

13

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Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19241058

publication date

25 February 2009

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Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19241058

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Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19241058

52

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http://europepmc.org/abstract/MED/19241058

5

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19 December 2017

http://europepmc.org/abstract/MED/19241058

834-843

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19 December 2017

http://europepmc.org/abstract/MED/19241058

https://scigraph.springernature.com/pub.10.1007/s00125-009-1290-2

0 references

The second activating glucokinase mutation (A456V): implications for glucose homeostasis and diabetes therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of type 2 diabetes by adenoviral-mediated overexpression of the glucokinase regulatory protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The genetic susceptibility to type 2 diabetes may be modulated by obesity status: implications for association studies

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https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The -30G>A polymorphism of the glucokinase gene promoter is associated with obesity in a population from southern Spain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The beta cell glucokinase promoter variant is an unlikely risk factor for diabetes mellitus. Diabetes Incidence Study in Sweden (DISS).

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A variation at position -30 of the beta-cell glucokinase gene promoter is associated with reduced beta-cell function in middle-aged Japanese-American men.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucokinase (GCK) mutations in hyper- and hypoglycemia: Maturity-onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemia of infancy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insights into the biochemical and genetic basis of glucokinase activation from naturally occurring hypoglycemia mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucokinase regulates reproductive function, glucocorticoid secretion, food intake, and hypothalamic gene expression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correct homeostasis model assessment (HOMA) evaluation uses the computer program

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Familial hyperglycemia due to mutations in glucokinase. Definition of a subtype of diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of glucokinase gene expression in the rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the glucokinase gene promoter in Japanese subjects with noninsulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neonatal diabetes mellitus due to complete glucokinase deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Banting Lecture 1995. A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical characteristics of Japanese men with glucokinase gene beta-cell promoter variant

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Familial hyperinsulinism caused by an activating glucokinase mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel polymorphisms in the GCKR gene and their influence on glucose and insulin levels in a Danish twin population

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A -30G>A polymorphism of the beta-cell-specific glucokinase promoter associates with hyperglycemia in the general population of whites.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The common P446L polymorphism in GCKR inversely modulates fasting glucose and triglyceride levels and reduces type 2 diabetes risk in the DESIR prospective general French population

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G(-30)A polymorphism in the pancreatic promoter of the glucokinase gene associated with angiographic coronary artery disease and type 2 diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distributions of C-reactive protein and its association with metabolic syndrome in middle-aged and older Chinese people

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of common type 2 diabetes risk polymorphisms in the DESIR prospective study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic impact of glucokinase overexpression in liver: lowering of blood glucose in fed rats is accompanied by hyperlipidemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice mutant for glucokinase regulatory protein exhibit decreased liver glucokinase: a sequestration mechanism in metabolic regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Severe persistent hyperinsulinemic hypoglycemia due to a de novo glucokinase mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid translocation of hepatic glucokinase in response to intraduodenal glucose infusion and changes in plasma glucose and insulin in conscious rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that glucokinase regulatory protein is expressed and interacts with glucokinase in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic factors for obesity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19241058

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00125-009-1290-2

1 reference

Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19241058

1 reference

Europe PubMed Central

19 December 2017

http://europepmc.org/abstract/MED/19241058

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