Insulin activates the PI3K-Akt survival pathway in vulnerable neurons following global brain ischemia. (Q46128356)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19203442%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

title

Insulin activates the PI3K-Akt survival pathway in vulnerable neurons following global brain ischemia (English)

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21 January 2020

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1

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21 January 2020

Rita Kumar

2

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21 January 2020

author name string

Alina C Murariu-Dobrin

3

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21 January 2020

Andrea B Page

4

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21 January 2020

Gary S Krause

5

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21 January 2020

Jonathon M Sullivan

6

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21 January 2020

publication date

6 February 2009

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21 January 2020

published in

Neurological Research

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21 January 2020

volume

31

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issue

9

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21 January 2020

page(s)

947-958

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Nervous system effects of cardiac arrest in monkeys. Preservation of vision

21 January 2020

cites work

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Insulin administration protects neurologic function in cerebral ischemia in rats.

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Insulin-induced normoglycemia improves ischemic outcome in hyperglycemic rats

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Insulin attenuates ischemic brain damage independent of its hypoglycemic effect.

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Mechanisms and consequences of activation of protein kinase B/Akt

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

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Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B

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Cellular survival: a play in three Akts

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Phosphoinositide 3-OH kinase/protein kinase B inhibits apoptotic cell death induced by reactive oxygen species in Saccharomyces cerevisiae.

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Models for studying long-term recovery following forebrain ischemia in the rat. 2. A 2-vessel occlusion model

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Unimpaired acquisition of spatial reference memory, but impaired homing performance in hippocampal-ablated pigeons

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Modality-specific retrograde amnesia of fear

21 January 2018

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Electrolytic lesions of the fimbria/fornix, dorsal hippocampus, or entorhinal cortex produce anterograde deficits in contextual fear conditioning in rats

21 January 2018

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Insulin induces dephosphorylation of eukaryotic initiation factor 2alpha and restores protein synthesis in vulnerable hippocampal neurons after transient brain ischemia

21 January 2018

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Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak

21 January 2018

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Reduction of ischemic brain injury by topical application of glial cell line-derived neurotrophic factor after permanent middle cerebral artery occlusion in rats

21 January 2018

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Evidence for and against a pivotal role of PI 3-kinase in a neuronal cell survival pathway

21 January 2018

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Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

21 January 2018

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Transient activation of Jun N-terminal kinases and protection from apoptosis by the insulin-like growth factor I receptor can be suppressed by dicumarol

21 January 2018

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Insulin-like Growth Factor 1 Inhibits Apoptosis Using the Phosphatidylinositol 3′-Kinase and Mitogen-activated Protein Kinase Pathways

21 January 2018

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21 January 2018

Identifiers

DOI

10.1179/174313209X382449

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19203442%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

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