Natural killer cells play a critical role in the immune response following immunization with melanoma-antigen-engineered dendritic cells (Q46144685)

19 December 2017

title

Natural killer cells play a critical role in the immune response following immunization with melanoma-antigen-engineered dendritic cells (English)

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19 December 2017

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Antoni Ribas

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object named as

Antoni Ribas

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19 December 2017

Jennifer Wargo

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object named as

Jennifer A Wargo

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19 December 2017

author name string

Lana Y Schumacher

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19 December 2017

Begonya Comin-Anduix

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Vivian B Dissette

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John A Glaspy

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William H McBride

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James S Economou

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publication date

1 June 2005

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19 December 2017

published in

Cancer Gene Therapy

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19 December 2017

volume

12

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19 December 2017

issue

6

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19 December 2017

page(s)

516-527

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Cancer immunotherapy using gene-modified dendritic cells.

cites work

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Human dendritic cells activate resting natural killer (NK) cells and are recognized via the NKp30 receptor by activated NK cells

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Genetically modified bone marrow-derived dendritic cells expressing tumor-associated viral or "self" antigens induce antitumor immunity in vivo

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Intratumoral injection of bone-marrow derived dendritic cells engineered to produce interleukin-12 induces complete regression of established murine transplantable colon adenocarcinomas

21 January 2018

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Murine dendritic cells transfected with human GP100 elicit both antigen-specific CD8(+) and CD4(+) T-cell responses and are more effective than DNA vaccines at generating anti-tumor immunity

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Generation of T-cell immunity to a murine melanoma using MART-1-engineered dendritic cells

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Characterization of antitumor immunization to a defined melanoma antigen using genetically engineered murine dendritic cells

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Immunosuppressive effects of interleukin-12 coexpression in melanoma antigen gene-modified dendritic cell vaccines

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7 January 2021

Dendritic cell-based genetic immunization in mice with a recombinant adenovirus encoding murine TRP2 induces effective anti-melanoma immunity

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7 January 2021

Therapy of established tumour with a hybrid cellular vaccine generated by using granulocyte-macrophage colony-stimulating factor genetically modified dendritic cells

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Enhanced therapeutic efficacy of tumor RNA-pulsed dendritic cells after genetic modification with lymphotactin

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7 January 2021

Dendritic cells transduced with wild-type p53 gene elicit potent anti-tumour immune responses

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7 January 2021

Disparate effect of beige mutation on cytotoxic function between natural killer and natural killer T cells

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Role of NK cells in the control of metastatic spread and growth of tumor cells in mice

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Identifiers

DOI

10.1038/SJ.CGT.7700818

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19 December 2017

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19 December 2017