Concentration-dependent effect of naringin on intestinal absorption of beta(1)-adrenoceptor antagonist talinolol mediated by p-glycoprotein and organic anion transporting polypeptide (Oatp). (Q46252123)

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English	Concentration-dependent effect of naringin on intestinal absorption of beta(1)-adrenoceptor antagonist talinolol mediated by p-glycoprotein and organic anion transporting polypeptide (Oatp).	scientific article

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scholarly article

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19002566

Concentration-dependent effect of naringin on intestinal absorption of beta(1)-adrenoceptor antagonist talinolol mediated by p-glycoprotein and organic anion transporting polypeptide (Oatp). (English)

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19002566

author name string

Yoshiyuki Shirasaka

1

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19002566

Yan Li

2

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19002566

Yuta Shibue

3

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19002566

Erika Kuraoka

4

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19002566

Hildegard Spahn-Langguth

5

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19002566

Yukio Kato

6

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19002566

Peter Langguth

7

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19002566

Ikumi Tamai

8

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19002566

publication date

12 November 2008

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Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19002566

Pharmaceutical Research

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19002566

26

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Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19002566

3

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Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19002566

560-567

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Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19002566

Molecular mechanisms of the naringin low uptake by intestinal Caco-2 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P-glycoprotein transporters and the gastrointestinal tract: evaluation of the potential in vivo relevance of in vitro data employing talinolol as model compound.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Active intestinal secretion of new quinolone antimicrobials and the partial contribution of P-glycoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic strategies in deciphering atypical drug absorption profiles

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative inhibitory effects of different compounds on rat oatpl (slc21a1)- and Oatp2 (Slc21a5)-mediated transport

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https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unexpected effect of verapamil on oral bioavailability of the beta-blocker talinolol in humans

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https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional intestinal permeability in rats of compounds with different physicochemical properties and transport mechanisms

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https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of P-glycoprotein expression levels on the concentration-dependent permeability of drugs to the cell membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transporter-mediated intestinal absorption of fexofenadine in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variation of flavonoids and furanocoumarins in grapefruit juices: a potential source of variability in grapefruit juice-drug interaction studies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical, cellular, and pharmacological aspects of the multidrug transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral bioavailability of digoxin is enhanced by talinolol: evidence for involvement of intestinal P-glycoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Scaling of in vitro membrane permeability to predict P-glycoprotein-mediated drug absorption in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Xenobiotic and endobiotic transporter mRNA expression in the blood-testis barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereoselective disposition of talinolol in man.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P-glycoprotein system as a determinant of drug interactions: the case of digoxin-verapamil

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of influx transporter for the quinolone antibacterial agent levofloxacin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective downregulation of the MDR1 gene product in Caco-2 cells by stable transfection to prove its relevance in secretory drug transport.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression, transport properties, and chromosomal location of organic anion transporter subtype 3

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of human organic anion transporting polypeptide OATP-B (SLC21A9) in pH-dependent transport across intestinal apical membrane.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Orange juice increased the bioavailability of pravastatin, 3-hydroxy-3-methylglutaryl CoA reductase inhibitor, in rats and healthy human subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The contribution of P-glycoprotein to pharmacokinetic drug-drug interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for intestinal secretion as an additional clearance pathway of talinolol enantiomers: concentration- and dose-dependent absorption in vitro and in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The talinolol double-peak phenomenon is likely caused by presystemic processing after uptake from gut lumen

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disposition and bioavailability of the beta 1-adrenoceptor antagonist talinolol in man.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bidirectional membrane transport: simulations of transport inhibition in uptake studies explain data obtained with flavonoids

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P-Glycoprotein, a gatekeeper in the blood-brain barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P-glycoprotein inhibitor erythromycin increases oral bioavailability of talinolol in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional Characterization of pH-Sensitive Organic Anion Transporting Polypeptide OATP-B in Human

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Grapefruit juice ingestion significantly reduces talinolol bioavailability

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of P-glycoprotein in drug disposition

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P-glycoprotein: a defense mechanism limiting oral bioavailability and CNS accumulation of drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pretreatment with potent P-glycoprotein ligands may increase intestinal secretion in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Site of drug absorption after oral administration: assessment of membrane permeability and luminal concentration of drugs in each segment of gastrointestinal tract

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of organic anion transporting polypeptide 1a5 (Oatp1a5) in the intestinal absorption of endothelin receptor antagonist in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonlinear intestinal absorption of 5-hydroxytryptamine receptor antagonist caused by absorptive and secretory transporters

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Grapefruit Juice–Drug Interactions: Grapefruit Juice and Its Components Inhibit P‐Glycoprotein (ABCB1) Mediated Transport of Talinolol in Caco‐2 Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carrier-mediated intestinal transport of drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gastrointestinal drug absorption: is it time to consider heterogeneity as well as homogeneity?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Grapefruit juice enhances intestinal absorption of the P-glycoprotein substrate talinolol

1 reference

https://pubmed.ncbi.nlm.nih.gov/19002566

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11095-008-9771-4

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19002566

1 reference

Europe PubMed Central

20 December 2017

http://europepmc.org/abstract/MED/19002566

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