Spironolactone suppresses inflammation and prevents L-NAME-induced renal injury in rats (Q46314707)

21 December 2017

title

Spironolactone suppresses inflammation and prevents L-NAME-induced renal injury in rats (English)

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21 December 2017

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Hirofumi Ikeda

1

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21 December 2017

Kazuhiko Tsuruya

2

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21 December 2017

Jiro Toyonaga

3

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21 December 2017

Kohsuke Masutani

4

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21 December 2017

Hideko Hayashida

5

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21 December 2017

Hideki Hirakata

6

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21 December 2017

Mitsuo Iida

7

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21 December 2017

language of work or name

English

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publication date

15 October 2008

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21 December 2017

published in

Kidney International

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21 December 2017

volume

75

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21 December 2017

issue

2

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21 December 2017

page(s)

147-155

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21 December 2017

https://scigraph.springernature.com/pub.10.1038/ki.2008.507

exact match

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cites work

The role of renin-angiotensin-aldosterone system in the progression of chronic kidney disease

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Effect of inhibitors of the renin-angiotensin system and other antihypertensive drugs on renal outcomes: systematic review and meta-analysis

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7 January 2021

Aldosterone/salt induces renal inflammation and fibrosis in hypertensive rats

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7 January 2021

Spironolactone ameliorates renal injury and connective tissue growth factor expression in type II diabetic rats

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7 January 2021

Therapeutic benefit of spironolactone in experimental chronic cyclosporine A nephrotoxicity.

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7 January 2021

Podocyte injury underlies the glomerulopathy of Dahl salt-hypertensive rats and is reversed by aldosterone blocker

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7 January 2021

Aldosterone antagonism ameliorates proteinuria and nephrosclerosis independent of glomerular dynamics in L-NAME/SHR model

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7 January 2021

Combination therapy with telmisartan and spironolactone alleviates L-NAME exacerbated nephrosclerosis with an increase in PPAR-gamma and decrease in TGF-beta(1).

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7 January 2021

RAAS escape: a real clinical entity that may be important in the progression of cardiovascular and renal disease

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7 January 2021

Long-term effects of spironolactone on proteinuria and kidney function in patients with chronic kidney disease

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7 January 2021

Sodium excess aggravates hypertension and renal parenchymal injury in rats with chronic NO inhibition

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7 January 2021

The role of nitric oxide and the renin-angiotensin system in salt-restricted Dahl rats

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7 January 2021

Mycophenolate Mofetil Reduces Renal Injury in the Chronic Nitric Oxide Synthase Inhibition Model

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7 January 2021

Chronic kidney disease progression.

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7 January 2021

MCP-1 and RANTES are expressed in renal cortex of rats chronically treated with nitric oxide synthase inhibitor. Involvement in macrophage and monocyte recruitment

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7 January 2021

Spironolactone prevents diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats

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https://api.crossref.org/works/10.1038%2FKI.2008.507

7 January 2021

Receptor-ligand interaction between CD44 and osteopontin (Eta-1)

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7 January 2021

A biochemical characterization of the binding of osteopontin to integrins alpha v beta 1 and alpha v beta 5

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7 January 2021

Tubular osteopontin expression in human glomerulonephritis and renal vasculitis

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7 January 2021

Intrarenal Renin-Angiotensin system is upregulated in experimental model of progressive renal disease induced by chronic inhibition of nitric oxide synthesis

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7 January 2021

Angiotensin blockade reverses hypertension during long-term nitric oxide synthase inhibition

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7 January 2021

Aldosterone enhances renin gene expression in juxtaglomerular cells

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7 January 2021

Aldosterone induces angiotensin converting enzyme gene expression via a JAK2-dependent pathway in rat endothelial cells

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7 January 2021

Regulation of angiotensin II receptor expression by nitric oxide in rat adrenal gland

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7 January 2021

The antagonism of aldosterone receptor prevents the development of hypertensive heart failure induced by chronic inhibition of nitric oxide synthesis in rats.

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https://api.crossref.org/works/10.1038%2FKI.2008.507

7 January 2021

Nitric oxide inhibits human aldosteronogenesis without guanylyl cyclase stimulation

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.507

7 January 2021

Nitric oxide inhibits aldosterone synthesis by a guanylyl cyclase-independent effect

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https://api.crossref.org/works/10.1038%2FKI.2008.507

7 January 2021

Chronic administration of nitric oxide reduces angiotensin II receptor type 1 expression and aldosterone synthesis in zona glomerulosa cells

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https://api.crossref.org/works/10.1038%2FKI.2008.507

7 January 2021

Measurement of steroid synthesis in zona glomerulosa cells by liquid chromatography-electrospray ionization-mass spectrometry: inhibition by nitric oxide

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.507

7 January 2021

Effect of spironolactone and captopril on nitric oxide and S-nitrosothiol formation in kidney of L-NAME-treated rats

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.507

7 January 2021

Salt Intake, Oxidative Stress, and Renal Expression of NADPH Oxidase and Superoxide Dismutase

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7 January 2021

Aldosterone induces a vascular inflammatory phenotype in the rat heart

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.507

7 January 2021

Aldosterone-induced inflammation in the rat heart : role of oxidative stress

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.507

7 January 2021

Osteopontin expression in angiotensin II-induced tubulointerstitial nephritis

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.507

7 January 2021

Renal expression of genes that promote interstitial inflammation and fibrosis in rats with protein-overload proteinuria

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.507

7 January 2021

Obstructive uropathy in the mouse: role of osteopontin in interstitial fibrosis and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.507

7 January 2021

Monocyte chemoattractant protein-1 and osteopontin differentially regulate monocytes recruitment in experimental glomerulonephritis

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.507

7 January 2021

Osteopontin in rat renal fibroblasts: functional properties and transcriptional regulation by aldosterone

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https://api.crossref.org/works/10.1038%2FKI.2008.507

7 January 2021

Effect of aldosterone on renal transforming growth factor-beta

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.507

7 January 2021

Mechanisms of tubulointerstitial fibrosis

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https://api.crossref.org/works/10.1038%2FKI.2008.507

7 January 2021

Transforming growth factor-beta regulates tubular epithelial-myofibroblast transdifferentiation in vitro

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https://api.crossref.org/works/10.1038%2FKI.2008.507

7 January 2021

Aldosterone induces epithelial-mesenchymal transition via ROS of mitochondrial origin

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https://api.crossref.org/works/10.1038%2FKI.2008.507

7 January 2021

Mesangial immune injury, hypertension, and progressive glomerular damage in Dahl rats.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.507

7 January 2021

Accumulation of 8-oxoguanine in the cellular DNA and the alteration of the OGG1 expression during ischemia-reperfusion injury in the rat kidney.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.507

7 January 2021

Identifiers

DOI

10.1038/KI.2008.507

1 reference

21 December 2017

Dimensions Publication ID

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21 December 2017