Ablation of proliferating microglia does not affect motor neuron degeneration in amyotrophic lateral sclerosis caused by mutant superoxide dismutase. (Q46325370)

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English	Ablation of proliferating microglia does not affect motor neuron degeneration in amyotrophic lateral sclerosis caused by mutant superoxide dismutase.	scientific article

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15 January 2020

Ablation of proliferating microglia does not affect motor neuron degeneration in amyotrophic lateral sclerosis caused by mutant superoxide dismutase (English)

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15 January 2020

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amyotrophic lateral sclerosis

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Jean-Nicolas Audet

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Ludo Van Den Bosch

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Jean-Pierre Julien

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Jean-Pierre Julien

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Genevíève Gowing

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15 January 2020

Thomas Philips

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Bart Van Wijmeersch

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15 January 2020

Maarten Dewil

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15 January 2020

An D Billiau

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Wim Robberecht

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1 October 2008

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15 January 2020

Journal of Neuroscience

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15 January 2020

10234-10244

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15 January 2020

Involvement of peritoneal macrophage in the induction of cytotoxicity due to apoptosis in ascitic fluid associated with severe acute pancreatitis

1 reference

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12 December 2020

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Reactive microgliosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

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Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer

1 reference

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12 December 2020

based on heuristic

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Amyotrophic lateral sclerosis. unfolding the toxicity of the misfolded

1 reference

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12 December 2020

based on heuristic

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Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

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Immune reactivity in a mouse model of familial ALS correlates with disease progression

1 reference

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12 December 2020

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Induction of proinflammatory molecules in mice with amyotrophic lateral sclerosis: no requirement for proapoptotic interleukin-1beta in neurodegeneration.

1 reference

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12 December 2020

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From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

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Innate immunity: the missing link in neuroprotection and neurodegeneration?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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Minocycline delays disease onset and mortality in a transgenic model of ALS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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Inflammation in neurodegenerative disease--a double-edged sword

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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Transient expansion of Mac1+Ly6-G+Ly6-C+ early myeloid cells with suppressor activity in spleens of murine radiation marrow chimeras: possible implications for the graft-versus-host and graft-versus-leukemia reactivity of donor lymphocyte infusions

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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Early activation of microglia as antigen-presenting cells correlates with T cell-mediated protection and repair of the injured central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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Exacerbation of motor neuron disease by chronic stimulation of innate immunity in a mouse model of amyotrophic lateral sclerosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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CD4-positive T cell-mediated neuroprotection requires dual compartment antigen presentation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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The arachidonic acid 5-lipoxygenase inhibitor nordihydroguaiaretic acid inhibits tumor necrosis factor alpha activation of microglia and extends survival of G93A-SOD1 transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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Cytoskeletal defects in amyotrophic lateral sclerosis (motor neuron disease).

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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Microglia as potential contributors to motor neuron injury in amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

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Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

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Mouse model for ablation of proliferating microglia in acute CNS injuries.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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The chemokine MCP-1 and the dendritic and myeloid cells it attracts are increased in the mSOD1 mouse model of ALS

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease

1 reference

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12 December 2020

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Thalidomide and lenalidomide extend survival in a transgenic mouse model of amyotrophic lateral sclerosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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Isolation and direct characterization of resident microglial cells from the normal and inflamed central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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Altered immune response to CNS viral infection in mice with a conditional knock-down of macrophage-lineage cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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Onset and progression in inherited ALS determined by motor neurons and microglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of excitotoxicity in the pathogenesis of amyotrophic lateral sclerosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absence of tumor necrosis factor-alpha does not affect motor neuron disease caused by superoxide dismutase 1 mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correction of humoral derangements from mutant superoxide dismutase 1 spinal cord

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel immune-based therapy for stroke induces neuroprotection and supports neurogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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Selective ablation of proliferating microglial cells exacerbates ischemic injury in the brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant SOD1(G93A) microglia are more neurotoxic relative to wild-type microglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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Heterogeneity in motoneuron disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

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Increased glioma growth in mice depleted of macrophages.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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Microglia: active sensor and versatile effector cells in the normal and pathologic brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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Adult glial precursor proliferation in mutant SOD1G93A mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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Local self-renewal can sustain CNS microglia maintenance and function throughout adult life.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

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Microglia in amyotrophic lateral sclerosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

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MyD88-deficient bone marrow cells accelerate onset and reduce survival in a mouse model of amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T cells in amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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Dynamics of the inflammatory response after murine spinal cord injury revealed by flow cytometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement of myeloid cells for axon regeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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Investigation of glial cells in semithin sections. I. Identification of glial cells in the brain of young rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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F4/80, a monoclonal antibody directed specifically against the mouse macrophage

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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The impact of microglia-derived cytokines upon gliosis in the CNS

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phagocytic microglia release cytokines and cytotoxins that regulate the survival of astrocytes and neurons in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactive astrocytes: cellular and molecular cues to biological function

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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Mature microglia resemble immature antigen-presenting cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

based on heuristic

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Dendritic cells and the control of immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18842883

12 December 2020

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The origin and differentiation of microglial cells during development

1 reference

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Identifiers

10.1523/JNEUROSCI.3494-08.2008

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15 January 2020

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24 November 2022

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15 January 2020

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15 January 2020

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