On the challenge of exploring the evolutionary trajectory from phosphotriesterase to arylesterase using computer simulations (Q46337805)

21 December 2017

title

On the challenge of exploring the evolutionary trajectory from phosphotriesterase to arylesterase using computer simulations (English)

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21 December 2017

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4

Arieh Warshel

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21 December 2017

3

Maria P Frushicheva

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21 December 2017

author name string

Ram Prasad Bora

series ordinal

1

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21 December 2017

Matthew J L Mills

series ordinal

2

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21 December 2017

language of work or name

English

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publication date

13 February 2015

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21 December 2017

Journal of Physical Chemistry B

published in

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21 December 2017

volume

119

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21 December 2017

issue

8

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21 December 2017

page(s)

3434-3445

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21 December 2017

Catalytic mechanisms for phosphotriesterases

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Maintenance of native-like protein dynamics may not be required for engineering functional proteins

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The catalytic effect of dihydrofolate reductase and its mutants is determined by reorganization energies

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The empirical valence bond as an effective strategy for computer-aided enzyme design

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Biocatalysis in organic chemistry and biotechnology: past, present, and future

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Identifiers

DOI

10.1021/JP5124025

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21 December 2017

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21 December 2017