C-Myc and its target FoxM1 are critical downstream effectors of constitutive androstane receptor (CAR) mediated direct liver hyperplasia (Q46362458)

21 December 2017

title

C-Myc and its target FoxM1 are critical downstream effectors of constitutive androstane receptor (CAR) mediated direct liver hyperplasia (English)

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21 December 2017

author

Andreas Trumpp

8

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21 December 2017

author name string

William E Blanco-Bose

1

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21 December 2017

Mark J Murphy

2

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21 December 2017

Armin Ehninger

3

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21 December 2017

Sandra Offner

4

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21 December 2017

Christelle Dubey

5

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21 December 2017

Wendong Huang

6

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21 December 2017

David D Moore

7

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21 December 2017

language of work or name

English

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publication date

1 October 2008

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21 December 2017

published in

Hepatology

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21 December 2017

volume

48

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21 December 2017

issue

4

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21 December 2017

page(s)

1302-1311

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21 December 2017

Cytochrome P450-based cancer gene therapy: recent advances and future prospects

cites work

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The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism

21 January 2018

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P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR.

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CAR, the continuously advancing receptor, in drug metabolism and disease

21 January 2018

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Tumor-promoting and hepatocarcinogenic effects of 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene (TCPOBOP) in DBA/2NCr and C57BL/6NCr mice and an apparent promoting effect on nasal cavity tumors but not on hepatocellular tumors in F344/NCr rats initiate

21 January 2018

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A common set of immediate-early response genes in liver regeneration and hyperplasia

21 January 2018

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The CAR nuclear receptor and hepatocyte proliferation

21 January 2018

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Xenobiotic stress induces hepatomegaly and liver tumors via the nuclear receptor constitutive androstane receptor

21 January 2018

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Loss of cyclin D1 does not inhibit the proliferative response of mouse liver to mitogenic stimuli.

21 January 2018

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FoxM1 is required for execution of the mitotic programme and chromosome stability

21 January 2018

1 reference

c-Myc regulates cell size and ploidy but is not essential for postnatal proliferation in liver

21 January 2018

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Developmental context determines latency of MYC-induced tumorigenesis

21 January 2018

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MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer

21 January 2018

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Transcriptional regulation and transformation by Myc proteins

21 January 2018

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The Myc trilogy: lord of RNA polymerases.

21 January 2018

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c-Myc regulates mammalian body size by controlling cell number but not cell size

21 January 2018

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Inducible gene targeting in mice

21 January 2018

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Targeted insertion of an IRES Cre into the Hnf4alpha locus: Cre-mediated recombination in the liver, kidney, and gut epithelium

21 January 2018

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c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation

21 January 2018

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RACE: Remote Analysis Computation for gene Expression data

21 January 2018

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DAVID: Database for Annotation, Visualization, and Integrated Discovery

21 January 2018

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From genomics to chemical genomics: new developments in KEGG

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Matrix attachment region-dependent function of the immunoglobulin mu enhancer involves histone acetylation at a distance without changes in enhancer occupancy

21 January 2018

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Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification

21 January 2018

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Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice

21 January 2018

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Functional inhibitory cross-talk between constitutive androstane receptor and hepatic nuclear factor-4 in hepatic lipid/glucose metabolism is mediated by competition for binding to the DR1 motif and to the common coactivators, GRIP-1 and PGC-1alpha

21 January 2018

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Preventing re-replication of chromosomal DNA.

21 January 2018

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Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells

21 January 2018

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Principles of CDK regulation

21 January 2018

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21 January 2018

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How do so few control so many?

21 January 2018

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Bub1 and the multilayered inhibition of Cdc20-APC/C in mitosis

21 January 2018

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The Forkhead Box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration

21 January 2018

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Gadd45beta is induced through a CAR-dependent, TNF-independent pathway in murine liver hyperplasia

21 January 2018

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Genomic targets of the human c-Myc protein

21 January 2018

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Skin epidermis lacking the c-Myc gene is resistant to Ras-driven tumorigenesis but can reacquire sensitivity upon additional loss of the p21Cip1 gene

21 January 2018

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Foxm1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor

21 January 2018

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FOXM1c and Sp1 transactivate the P1 and P2 promoters of human c-myc synergistically

21 January 2018

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A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells

21 January 2018

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Transplanted hepatocytes over-expressing FoxM1B efficiently repopulate chronically injured mouse liver independent of donor age.

21 January 2018

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More than just proliferation: Myc function in stem cells

21 January 2018

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Nuclear receptor-dependent bile acid signaling is required for normal liver regeneration

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

FOXM1c transactivates the human c-myc promoter directly via the two TATA boxes P1 and P2

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1002/HEP.22475

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21 December 2017

PubMed ID

18798339

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21 December 2017