Tyrosinase exacerbates dopamine toxicity but is not genetically associated with Parkinson's disease (Q46386596)

21 December 2017

title

Tyrosinase exacerbates dopamine toxicity but is not genetically associated with Parkinson's disease (English)

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21 December 2017

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7

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Luigi Bubacco

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Mark R Cookson

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Mark R Cookson

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8

Andrew Singleton

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13

Alexandra Beilina

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Gertrude-Emilia Costin

5

Gertrude-Emilia Costin

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21 December 2017

David W. Miller

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David W Miller

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21 December 2017

Olli Hellström

10

Olli Hellström

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Johanna Eerola

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Johanna Eerola

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Elisa Greggio

1

Elisa Greggio

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21 December 2017

author name string

Elisabetta Bergantino

2

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Donald Carter

3

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21 December 2017

Rili Ahmad

4

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Vincent J Hearing

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Pentti J Tienari

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language of work or name

English

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publication date

1 April 2005

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21 December 2017

Journal of Neurochemistry

published in

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volume

93

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21 December 2017

issue

1

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page(s)

246-256

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21 December 2017

Dopamine oxidation alters mitochondrial respiration and induces permeability transition in brain mitochondria: implications for Parkinson's disease

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A common temperature-sensitive allelic form of human tyrosinase is retained in the endoplasmic reticulum at the nonpermissive temperature.

21 January 2018

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Catechol ortho-quinones: the electrophilic compounds that form depurinating DNA adducts and could initiate cancer and other diseases.

21 January 2018

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Paraoxonase 1 (PON1) gene polymorphisms and Parkinson's disease in a Finnish population

21 January 2018

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Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct

21 January 2018

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Tyrosinase gene expression is not detected in mouse brain outside the retinal pigment epithelium cells

21 January 2018

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Confirmation of the protective effect of iNOS in an independent cohort of Parkinson disease.

21 January 2018

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Proper folding and endoplasmic reticulum to golgi transport of tyrosinase are induced by its substrates, DOPA and tyrosine

21 January 2018

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Increased dopamine and its metabolites in SH‐SY5Y neuroblastoma cells that express tyrosinase

21 January 2018

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Mammalian tyrosinase. A comparison of tyrosine hydroxylation and melanin formation

21 January 2018

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Inhibition of tyrosinase reduces cell viability in catecholaminergic neuronal cells

21 January 2018

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A human TERT C-terminal polypeptide sensitizes HeLa cells to H2O2-induced senescence without affecting telomerase enzymatic activity.

21 January 2018

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Does tyrosinase exist in neuromelanin-pigmented neurons in the human substantia nigra?

21 January 2018

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Assembly, target-signaling and intracellular transport of tyrosinase gene family proteins in the initial stage of melanosome biogenesis

21 January 2018

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Inverse relationship between the contents of neuromelanin pigment and the vesicular monoamine transporter-2: human midbrain dopamine neurons

21 January 2018

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Environmental risk factors and Parkinson's disease: selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat

21 January 2018

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L166P mutant DJ-1, causative for recessive Parkinson's disease, is degraded through the ubiquitin-proteasome system

21 January 2018

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Conformation-dependent post-translational glycosylation of tyrosinase. Requirement of a specific interaction involving the CuB metal binding site

21 January 2018

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Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons

21 January 2018

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The dark side of lysosome-related organelles: specialization of the endocytic pathway for melanosome biogenesis

21 January 2018

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Tyrosinase enhances the covalent modification of DNA by dopamine

21 January 2018

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Vesicles: equal in neurotransmitter concentration but not in volume.

21 January 2018

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Neuromelanin biosynthesis is driven by excess cytosolic catecholamines not accumulated by synaptic vesicles.

21 January 2018

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New evidence for presence of tyrosinase in substantia nigra, forebrain and midbrain

21 January 2018

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Production of melanocyte-specific antibodies to human melanosomal proteins: expression patterns in normal human skin and in cutaneous pigmented lesions

21 January 2018

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Reaction of oxidized dopamine with endogenous cysteine residues in the human dopamine transporter.

21 January 2018

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Tyrosinase mRNA is expressed in human substantia nigra

21 January 2018

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Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseases

21 January 2018

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Neuromelanin of the substantia nigra: a neuronal black hole with protective and toxic characteristics

21 January 2018

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10.1111/J.1471-4159.2005.03019.X

21 January 2018

Identifiers

DOI

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21 December 2017

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21 December 2017