Pol eta is required for DNA replication during nucleotide deprivation by hydroxyurea (Q46406774)

21 December 2017

title

Pol eta is required for DNA replication during nucleotide deprivation by hydroxyurea (English)

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21 December 2017

4

Karentz D

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21 December 2017

author name string

de Feraudy S

1

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21 December 2017

Limoli CL

2

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21 December 2017

Giedzinski E

3

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21 December 2017

Marti TM

5

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21 December 2017

Feeney L

6

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21 December 2017

Cleaver JE

7

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21 December 2017

language of work or name

English

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publication date

19 March 2007

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21 December 2017

published in

Oncogene

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21 December 2017

volume

26

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21 December 2017

issue

39

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21 December 2017

page(s)

5713-5721

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21 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1210385

exact match

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cites work

Inhibition of DNA synthesis is a potent mechanism by which cytostatic drugs induce homologous recombination in mammalian cells

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Impaired translesion synthesis in xeroderma pigmentosum variant extracts

21 January 2018

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Comparison of hypoxia-induced replication arrest with hydroxyurea and aphidicolin-induced arrest

21 January 2018

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Effects of hydroxyurea and aphidicolin on phosphorylation of ataxia telangiectasia mutated on Ser 1981 and histone H2AX on Ser 139 in relation to cell cycle phase and induction of apoptosis

21 January 2018

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DNA replication arrest in XP variant cells after UV exposure is diverted into an Mre11-dependent recombination pathway by the kinase inhibitor wortmannin

21 January 2018

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DNA double-strand breaks associated with replication forks are predominantly repaired by homologous recombination involving an exchange mechanism in mammalian cells

21 January 2018

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7 January 2021

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

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7 January 2021

Molecular analysis of mutations in DNA polymerase eta in xeroderma pigmentosum-variant patients

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7 January 2021

Eukaryotic DNA polymerases: proposal for a revised nomenclature.

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7 January 2021

Mechanisms of drug resistance to inhibitors directed at the individual subunits of ribonucleotide reductase.

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7 January 2021

Analysis of DNA replication forks encountering a pyrimidine dimer in the template to the leading strand

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7 January 2021

Activation of mammalian Chk1 during DNA replication arrest: a role for Chk1 in the intra-S phase checkpoint monitoring replication origin firing

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7 January 2021

Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes.

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7 January 2021

Y-family DNA polymerases respond to DNA damage-independent inhibition of replication fork progression

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7 January 2021

Amplification of the genes for both components of ribonucleotide reductase in hydroxyurea resistant mammalian cells

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7 January 2021

hRAD30 mutations in the variant form of xeroderma pigmentosum

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7 January 2021

Domain structure, localization, and function of DNA polymerase eta, defective in xeroderma pigmentosum variant cells

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7 January 2021

Synchronization in the cell cycle by inhibitors of DNA replication induces histone H2AX phosphorylation: an indication of DNA damage.

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7 January 2021

UV-induced replication arrest in the xeroderma pigmentosum variant leads to DNA double-strand breaks, gamma -H2AX formation, and Mre11 relocalization

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7 January 2021

Alternative recombination pathways in UV-irradiated XP variant cells

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7 January 2021

Polymerase eta deficiency in the xeroderma pigmentosum variant uncovers an overlap between the S phase checkpoint and double-strand break repair

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7 January 2021

DNA repair: the importance of phosphorylating histone H2AX.

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7 January 2021

Cell apoptosis: requirement of H2AX in DNA ladder formation, but not for the activation of caspase-3.

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7 January 2021

H2AX phosphorylation within the G1 phase after UV irradiation depends on nucleotide excision repair and not DNA double-strand breaks

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7 January 2021

The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta

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7 January 2021

DNA-PK phosphorylates histone H2AX during apoptotic DNA fragmentation in mammalian cells

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7 January 2021

A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210385

7 January 2021

Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways

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7 January 2021

Replication protein A and the Mre11.Rad50.Nbs1 complex co-localize and interact at sites of stalled replication forks

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7 January 2021

Characterization of homologous recombination induced by replication inhibition in mammalian cells

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7 January 2021

DNA polymerase eta undergoes alternative splicing, protects against UV sensitivity and apoptosis, and suppresses Mre11-dependent recombination

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7 January 2021

Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210385

7 January 2021

The mechanism of nucleotide incorporation by human DNA polymerase eta differs from that of the yeast enzyme.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210385

7 January 2021

ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210385

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210385

1 reference

21 December 2017

Dimensions Publication ID

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1 reference

21 December 2017