Comparative effects of estradiol, methyl-piperidino-pyrazole, raloxifene, and ICI 182 780 on gene expression in the murine uterus. (Q46480005)

http://europepmc.org/abstract/MED/18632874

22 December 2017

title

Comparative effects of estradiol, methyl-piperidino-pyrazole, raloxifene, and ICI 182 780 on gene expression in the murine uterus (English)

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11 May 2020

author name string

Angela M Davis

1

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11 May 2020

Jiude Mao

2

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11 May 2020

Bushra Naz

3

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11 May 2020

Jessica A Kohl

4

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11 May 2020

Cheryl S Rosenfeld

5

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11 May 2020

publication date

16 July 2008

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http://europepmc.org/abstract/MED/18632874

22 December 2017

published in

Journal of Molecular Endocrinology

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11 May 2020

volume

41

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11 May 2020

issue

4

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11 May 2020

page(s)

205-217

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Selective estrogen receptor modulators: Women's panacea for the next millennium?

11 May 2020

cites work

1 reference

12 December 2020

Uterotrophic effects of tamoxifen, toremifene, and raloxifene do not predict endometrial cell proliferation in the ovariectomized CD1 mouse.

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12 December 2020

The interaction of raloxifene and the active metabolite of the antiestrogen EM-800 (SC 5705) with the human estrogen receptor.

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12 December 2020

Effect of estradiol on estrogen receptor expression in rat uterine cell types

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12 December 2020

The endometrial effects of SERMs

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12 December 2020

ICI 182,780 (Faslodex): development of a novel, "pure" antiestrogen

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12 December 2020

Effect of single and compound knockouts of estrogen receptors alpha (ERalpha) and beta (ERbeta) on mouse reproductive phenotypes

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Raloxifene hydrochloride

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Cardiovascular effects of raloxifene hydrochloride.

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Phytoestrogens and carcinogenesis-differential effects of genistein in experimental models of normal and malignant rat endometrium

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Paradoxical interactions among estrogen receptors, estrogens and SERMS: mutual annihilation and synergy

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12 December 2020

ICI 182,780 acts as a partial agonist and antagonist of estradiol effects in specific cells of the sheep uterus

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12 December 2020

Comparisons of the effects of tamoxifen, toremifene and raloxifene on enzyme induction and gene expression in the ovariectomised rat uterus

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12 December 2020

Antagonists selective for estrogen receptor alpha

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12 December 2020

Patterns of episialin/MUC1 expression in endometrial carcinomas and prognostic relevance

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12 December 2020

Synergistic inhibitory effects of genistein and tamoxifen on human dysplastic and malignant epithelial breast cells in vitro

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12 December 2020

Comparison of the effects of EM-652 (SCH57068), tamoxifen, toremifene, droloxifene, idoxifene, GW-5638 and raloxifene on the growth of human ZR-75-1 breast tumors in nude mice

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Regulation of estrogen target genes and growth by selective estrogen-receptor modulators in endometrial cancer cells

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12 December 2020

A review of selective estrogen receptor modulators in the treatment of breast and endometrial cancer.

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12 December 2020

Estrogen and selective estrogen receptor modulator regulation of insulin-like growth factor binding protein 5 in the rat uterus

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12 December 2020

Treatment of rats with 17beta-estradiol or relaxin rapidly inhibits uterine estrogen receptor beta1 and beta2 messenger ribonucleic acid levels

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12 December 2020

Antiestrogens and selective estrogen receptor modulators as multifunctional medicines. 2. Clinical considerations and new agents

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Estrogen receptor-alpha dependency of estrogen's stimulatory action on cancellous bone formation in male mice

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12 December 2020

Effects of SERM (selective estrogen receptor modulator) treatment on growth and proliferation in the rat uterus

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12 December 2020

Analysis of temporal changes in the expression of estrogen-regulated genes in the uterus

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12 December 2020

Estrogen receptor-dependent genomic responses in the uterus mirror the biphasic physiological response to estrogen

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12 December 2020

Identification of temporal patterns of gene expression in the uteri of immature, ovariectomized mice following exposure to ethynylestradiol

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12 December 2020

Activities of estrogen receptor alpha- and beta-selective ligands at diverse estrogen responsive gene sites mediating transactivation or transrepression

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12 December 2020

Transcription profiling of estrogen target genes in young and old mouse uterus

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12 December 2020

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12 December 2020

Estrogen signaling: a subtle balance between ER alpha and ER beta

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12 December 2020

Comparative study of the short-term effects of a novel selective estrogen receptor modulator, ospemifene, and raloxifene and tamoxifen on rat uterus

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12 December 2020

Tissue-specific estrogenic and non-estrogenic effects of a xenoestrogen, nonylphenol.

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12 December 2020

Single-chain estrogen receptors (ERs) reveal that the ERalpha/beta heterodimer emulates functions of the ERalpha dimer in genomic estrogen signaling pathways

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12 December 2020

Differential effects of estrogen and raloxifene on messenger RNA and matrix metalloproteinase 2 activity in the rat uterus

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12 December 2020

Oestrogen-modulated gene expression in the human endometrium.

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12 December 2020

Estrogen receptor alpha and beta heterodimers exert unique effects on estrogen- and tamoxifen-dependent gene expression in human U2OS osteosarcoma cells.

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12 December 2020

Differences in gene expression in the proliferative human endometrium

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12 December 2020

Evaluation of the gene expression changes induced by 17-alpha-ethynyl estradiol in the immature uterus/ovaries of the rat using high density oligonucleotide arrays

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12 December 2020

Relative transcript quantification by quantitative PCR: roughly right or precisely wrong?

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12 December 2020

Estrogen and raloxifene, a selective estrogen receptor modulator, ameliorate renal damage in db/db mice

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12 December 2020

Effect of estradiol and raloxifene on MUC1 expression and adhesive properties of Ishikawa cells.

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12 December 2020

Complex agonist-like properties of ICI 182,780 (Faslodex) in human breast cancer cells that predominantly express progesterone receptor-B: implications for treatment resistance.

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12 December 2020

The anti-oestrogen ICI 182,780, but not tamoxifen, inhibits the growth of MCF-7 breast cancer cells refractory to long-term oestrogen deprivation through down-regulation of oestrogen receptor and IGF signalling.

1 reference

12 December 2020

Downregulation of estrogen receptor gene expression by exogenous 17beta-estradiol in the mammary glands of lactating mice

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12 December 2020

Estrogen receptor alpha mediates 17alpha-ethynylestradiol causing hepatotoxicity

1 reference

12 December 2020

The effects of the selective estrogen receptor modulators, methyl-piperidino-pyrazole (MPP), and raloxifene in normal and cancerous endometrial cell lines and in the murine uterus

1 reference

12 December 2020

Estrogen receptor (ER)-beta isoforms: a key to understanding ER-beta signaling

1 reference

12 December 2020

Estrogenic agonist activity of ICI 182,780 (Faslodex) in hippocampal neurons: implications for basic science understanding of estrogen signaling and development of estrogen modulators with a dual therapeutic profile

1 reference

12 December 2020

The role of the estrogen receptor in uterine epithelial proliferation and cytodifferentiation in neonatal mice

1 reference

12 December 2020

Identification of estrogen-regulated genes by microarray analysis of the uterus of immature rats exposed to endocrine disrupting chemicals

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12 December 2020

The expression of Hedgehog genes (Ihh, Dhh) and Hedgehog target genes (Ptc1, Gli1, Coup-TfII) is affected by estrogenic stimuli in the uterus of immature female rats

1 reference

12 December 2020

Transcription of estrogen receptor alpha and beta in mouse cerebral cortex: effect of age, sex, 17beta-estradiol and testosterone.

1 reference

12 December 2020

ICI 182,780 has agonistic effects and synergizes with estradiol-17 beta in fish liver, but not in testis.

1 reference

12 December 2020

Estrogen-dependent expression of the tissue kallikrein gene (Klk1) in the mouse uterus and its implications for endometrial tissue growth.

1 reference

12 December 2020

Soy phytochemicals synergistically enhance the preventive effect of tamoxifen on the growth of estrogen-dependent human breast carcinoma in mice

1 reference

12 December 2020

Influence of estrogens and antiestrogens on the expression of selected hormone-responsive genes

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12 December 2020

Estrogenic effects of mixtures of phyto- and synthetic chemicals on uterine growth of prepubertal rats

1 reference

12 December 2020

Estradiol, progesterone, and genistein inhibit oocyte nest breakdown and primordial follicle assembly in the neonatal mouse ovary in vitro and in vivo.

1 reference

12 December 2020

Nonclassical estrogen receptor alpha signaling mediates negative feedback in the female mouse reproductive axis

1 reference

12 December 2020

Comparative temporal and dose-dependent morphological and transcriptional uterine effects elicited by tamoxifen and ethynylestradiol in immature, ovariectomized mice

1 reference

12 December 2020

Short-term environmental enrichment decreases the mnemonic response to estrogen in young, but not aged, female mice.

1 reference

12 December 2020

Ultrasensitive cell-based bioassay for the measurement of global estrogenic activity of flavonoid mixtures revealing additive, restrictive, and enhanced actions in binary and higher order combinations

1 reference

12 December 2020

Definition of functionally important mechanistic differences among selective estrogen receptor down-regulators

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12 December 2020

Estrogen regulation of tissue-specific expression of complement C3.

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12 December 2020

Lactotransferrin is the major estrogen inducible protein of mouse uterine secretions.

1 reference

12 December 2020

Effect of oestradiol on cell proliferation and histological changes in the uterus and vagina of mice

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12 December 2020

The proliferative action of oestriol

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12 December 2020

Expression and steroid hormonal control of Muc-1 in the mouse uterus.

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12 December 2020

Unique response pathways are established by allosteric interactions among nuclear hormone receptors

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12 December 2020

Estradiol-induced down-regulation of estrogen receptor. Effect of various modulators of protein synthesis and expression

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12 December 2020

Antiuterotrophic effects of the pure antioestrogen ICI 182,780 in adult female monkeys (Macaca nemestrina): quantitative magnetic resonance imaging

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12 December 2020

Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene

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12 December 2020

Long-term effects of neonatal treatment with progesterone, alone and in combination with estrogen, on the mammary gland and reproductive tract of female BALB/cfC3H mice

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12 December 2020

Tissue kallikrein and the bradykinin B2 receptor are expressed in endometrial and prostate cancers

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12 December 2020

Estrogen receptors alpha and beta form heterodimers on DNA

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12 December 2020

The novel estrogen receptor-beta subtype: potential role in the cell- and promoter-specific actions of estrogens and anti-estrogens

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12 December 2020

Mouse estrogen receptor beta forms estrogen response element-binding heterodimers with estrogen receptor alpha.

1 reference

12 December 2020

Raloxifene: magic bullet for heart and bone?

1 reference

12 December 2020

Oestradiol up-regulates oestrogen receptor, cyclophilin, and glyceraldehyde phosphate dehydrogenase mRNA concentrations in endometrium, but down-regulates them in liver.

1 reference

12 December 2020

Estrogen- and antiestrogen-responsiveness of HEC1A endometrial adenocarcinoma cells in culture.

1 reference

12 December 2020

Phytoestrogens have agonistic and combinatorial effects on estrogen-responsive gene expression in MCF-7 human breast cancer cells.

1 reference

12 December 2020

Comparative distribution of estrogen receptor-alpha (ER-alpha) and beta (ER-beta) mRNA in the rat pituitary, gonad, and reproductive tract.

1 reference

12 December 2020

Generation and reproductive phenotypes of mice lacking estrogen receptor beta

1 reference

12 December 2020

Identifiers

DOI

10.1677/JME-08-0029

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6697483&resulttype=core&format=json

11 May 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6697483&resulttype=core&format=json

11 May 2020

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