Nutrient regulation of PKCepsilon is mediated by leucine, not insulin, in skeletal muscle. (Q46484199)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15886222%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

title

Nutrient regulation of PKCepsilon is mediated by leucine, not insulin, in skeletal muscle (English)

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11 January 2020

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4

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11 January 2020

author name string

Thomas C Vary

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15886222%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Stacy Goodman

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15886222%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Laurie E Kilpatrick

series ordinal

3

1 reference

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11 January 2020

publication date

10 May 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15886222%20AND%20SRC:MED&resulttype=core&format=json

American Journal of Physiology - Endocrinology and Metabolism

11 January 2020

published in

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11 January 2020

volume

289

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11 January 2020

issue

4

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11 January 2020

page(s)

E684-94

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Role of protein kinase Cdelta in transmitting hypoxia signal to HSF and HIF-1.

11 January 2020

cites work

1 reference

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Amino acids and insulin are both required to regulate assembly of the eIF4E. eIF4G complex in rat skeletal muscle

21 January 2018

1 reference

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Increase in anterior tibialis muscle protein synthesis in healthy man during mixed amino acid infusion: studies of incorporation of [1-13C]leucine.

21 January 2018

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Phosphorylation of threonine 638 critically controls the dephosphorylation and inactivation of protein kinase Calpha.

21 January 2018

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Mechanism of action of the immunosuppressant rapamycin

21 January 2018

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Regulation of conventional protein kinase C isozymes by phosphoinositide-dependent kinase 1 (PDK-1)

21 January 2018

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Differential responsiveness of protein synthesis and degradation to amino acid availability in humans.

21 January 2018

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Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism

21 January 2018

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Insulin-like growth factor I accelerates protein synthesis in skeletal muscle during sepsis

21 January 2018

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Protein kinase C is regulated in vivo by three functionally distinct phosphorylations

21 January 2018

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Regulation of protein synthesis by branched-chain amino acids

21 January 2018

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Leucine regulates translation of specific mRNAs in L6 myoblasts through mTOR-mediated changes in availability of eIF4E and phosphorylation of ribosomal protein S6.

21 January 2018

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Alcohol impairs leucine-mediated phosphorylation of 4E-BP1, S6K1, eIF4G, and mTOR in skeletal muscle

21 January 2018

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Influence of amino acid availability on protein turnover in perfused skeletal muscle

21 January 2018

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Identification of serine 643 of protein kinase C-delta as an important autophosphorylation site for its enzymatic activity.

21 January 2018

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Tissue-specific effects of chronic dietary leucine and norleucine supplementation on protein synthesis in rats

21 January 2018

1 reference

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Mammalian TOR controls one of two kinase pathways acting upon nPKCdelta and nPKCepsilon

21 January 2018

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Bidirectional modulation of insulin action by amino acids

21 January 2018

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Structural requirement of leucine for activation of p70 S6 kinase

21 January 2018

1 reference

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Distinctive activation mechanisms and functions for protein kinase Cdelta

21 January 2018

1 reference

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Physical and functional interactions between protein tyrosine phosphatase alpha, PI 3-kinase, and PKCdelta

21 January 2018

1 reference

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Effects of amino acids on synthesis and degradation of skeletal muscle proteins in humans.

21 January 2018

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Differential effects of hyperinsulinemia and hyperaminoacidemia on leucine-carbon metabolism in vivo. Evidence for distinct mechanisms in regulation of net amino acid deposition

21 January 2018

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Amino acid-induced stimulation of translation initiation in rat skeletal muscle

21 January 2018

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Insulin fails to stimulate muscle protein synthesis in sepsis despite unimpaired signaling to 4E-BP1 and S6K1.

21 January 2018

1 reference

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Effects of chronic alcohol consumption on regulation of myocardial protein synthesis

21 January 2018

1 reference

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Restoration of protein synthesis in heart and skeletal muscle after withdrawal of alcohol

21 January 2018

1 reference

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Differential effects of alcohol consumption on eukaryotic elongation factors in heart, skeletal muscle, and liver

21 January 2018

1 reference

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Amino acid availability regulates p70 S6 kinase and multiple translation factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00613.2004

Rapamycin-sensitive phosphorylation of PKC on a carboxy-terminal site by an atypical PKC complex

21 January 2018

1 reference

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10.1152/AJPENDO.00613.2004

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15886222%20AND%20SRC:MED&resulttype=core&format=json

release_rpiwuqqsrffqrnetuopfjfckn4

11 January 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/rpiwuqqsrffqrnetuopfjfckn4

mapped directly with Wikidata item

24 November 2022

based on heuristic

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