Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages (Q46485595)

http://europepmc.org/abstract/PMC/5863951

29 June 2018

title

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages (English)

1 reference

http://europepmc.org/abstract/PMC/5863951

29 June 2018

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1 reference

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18

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Ana S.H. Costa

4

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Jan Henry Matthias Däbritz

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8

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Eyal Gottlieb

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Isabel Latorre

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Sinéad C Corr

11

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1 June 2020

Howard Jacobs

14

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Thomas Braun

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Michael P. Murphy

19

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1 June 2020

Luke A. J. O'Neill

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1 June 2020

16

Ramnik J Xavier

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1 June 2020

15

Marten Szibor

1 reference

1 June 2020

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Evanna L Mills

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Beth Kelly

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Angela Logan

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Mukund Varma

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Clare E Bryant

6

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Panagiotis Tourlomousis

7

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Gavin McManus

12

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Dylan Ryan

13

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1 June 2020

language of work or name

English

0 references

publication date

22 September 2016

1 reference

http://europepmc.org/abstract/PMC/5863951

29 June 2018

published in

Cell

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1 June 2020

volume

167

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1 June 2020

page(s)

457-470.e13

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1 June 2020

issue

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27667687%20AND%20SRC:MED&resulttype=core&format=json

Mitochondrial respiratory-chain adaptations in macrophages contribute to antibacterial host defense.

1 June 2020

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Mitochondrial ROS Produced via Reverse Electron Transport Extend Animal Lifespan

30 June 2018

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30 June 2018

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Oxygen Sensing by Arterial Chemoreceptors Depends on Mitochondrial Complex I Signaling.

30 June 2018

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Metformin Inhibits the Production of Reactive Oxygen Species from NADH:Ubiquinone Oxidoreductase to Limit Induction of Interleukin-1β (IL-1β) and Boosts Interleukin-10 (IL-10) in Lipopolysaccharide (LPS)-activated Macrophages.

30 June 2018

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Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization

30 June 2018

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Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.

30 June 2018

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Mitochondrial complex I activity suppresses inflammation and enhances bone resorption by shifting macrophage-osteoclast polarization

30 June 2018

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TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation

30 June 2018

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Succinate: a new epigenetic hacker

30 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5863951

Succinate is an inflammatory signal that induces IL-1β through HIF-1α.

30 June 2018

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Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling.

30 June 2018

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Alternative oxidase expression in the mouse enables bypassing cytochrome c oxidase blockade and limits mitochondrial ROS overproduction

30 June 2018

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Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells.

30 June 2018

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TLR signalling augments macrophage bactericidal activity through mitochondrial ROS.

30 June 2018

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30 June 2018

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30 June 2018

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30 June 2018

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Loss of the SdhB, but Not the SdhA, subunit of complex II triggers reactive oxygen species-dependent hypoxia-inducible factor activation and tumorigenesis.

30 June 2018

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STUDIES ON SUCCINATE DEHYDROGENASE. I. SPECTRAL PROPERTIES OF THE PURIFIED ENZYME AND FORMATION OF ENZYME-COMPETITIVE INHIBITOR COMPLEXES

30 June 2018

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Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

30 June 2018

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Site of action of lipid A on mitochondria.

30 June 2018

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Action of bacterial endotoxin and lipid A on mitochondrial enzyme activities of cells in culture and subcellular fractions

30 June 2018

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DeltaPsi(m)-Dependent and -independent production of reactive oxygen species by rat brain mitochondria

30 June 2018

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Interleukin 10 (IL-10) upregulates IL-1 receptor antagonist production from lipopolysaccharide-stimulated human polymorphonuclear leukocytes by delaying mRNA degradation

15 August 2018

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Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation

15 August 2018

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Titrating the effects of mitochondrial complex I impairment in the cell physiology

1 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27667687

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The interaction of energy and electron transfer reactions in mitochondria. I. General properties and nature of the products of succinate-linked reduction of pyridine nucleotide

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27667687

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELL.2016.08.064

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27667687%20AND%20SRC:MED&resulttype=core&format=json

release_ac6mcpp42vhkvgtlfywwojxcya

1 June 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ac6mcpp42vhkvgtlfywwojxcya

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27667687%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

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