Engineering conformational destabilization into mouse apolipoprotein E. A model for a unique property of human apolipoprotein E4. (Q46487763)

22 December 2017

title

Engineering conformational destabilization into mouse apolipoprotein E. A model for a unique property of human apolipoprotein E4. (English)

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22 December 2017

author

Danny M. Hatters

series ordinal

1

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22 December 2017

author name string

Clare A Peters-Libeu

series ordinal

2

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22 December 2017

Karl H Weisgraber

series ordinal

3

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22 December 2017

language of work or name

English

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publication date

11 May 2005

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22 December 2017

Journal of Biological Chemistry

published in

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22 December 2017

volume

280

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22 December 2017

issue

28

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22 December 2017

page(s)

26477-26482

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22 December 2017

Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Apolipoprotein E and Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Apolipoprotein E epsilon 4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Synergistic effects of traumatic head injury and apolipoprotein-epsilon 4 in patients with Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Apolipoprotein E epsilon4 and the risk of dementia with stroke. A population-based investigation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Association of apolipoprotein E polymorphism with outcome after head injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Apolipoprotein E genotype related differences in brain lesions of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Human apolipoprotein E4 domain interaction. Arginine 61 and glutamic acid 255 interact to direct the preference for very low density lipoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Apolipoprotein E4 domain interaction occurs in living neuronal cells as determined by fluorescence resonance energy transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Differences in stability among the human apolipoprotein E isoforms determined by the amino-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Apolipoprotein E4 forms a molten globule. A potential basis for its association with disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Comparison of the stabilities and unfolding pathways of human apolipoprotein E isoforms by differential scanning calorimetry and circular dichroism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Lipid binding ability of human apolipoprotein E N-terminal domain isoforms: correlation with protein stability?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Introduction of human apolipoprotein E4 "domain interaction" into mouse apolipoprotein E

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Functional characterization of apolipoprotein E isoforms overexpressed in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Automated MAD and MIR structure solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Refinement of macromolecular structures by the maximum-likelihood method

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Determination and analysis of urea and guanidine hydrochloride denaturation curves

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Three-dimensional structure of the LDL receptor-binding domain of human apolipoprotein E

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Conformational flexibility in the apolipoprotein E amino-terminal domain structure determined from three new crystal forms: Implications for lipid binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Kinetics of lipid-protein interactions: interaction of apolipoprotein A-I from human plasma high density lipoproteins with phosphatidylcholines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Effects of polymorphism on the lipid interaction of human apolipoprotein E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Protein subunit interactions and structural integrity of amyloidogenic transthyretins: evidence from electrospray mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Amyloid fibrils from muscle myoglobin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Is Alzheimer's disease an apolipoprotein E amyloidosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Expression of human apolipoprotein E reduces amyloid-beta deposition in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Role of apoE/Abeta interactions in Alzheimer's disease: insights from transgenic mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

A nontransgenic mouse model shows inducible amyloid-beta (Abeta) peptide deposition and elucidates the role of apolipoprotein E in the amyloid cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Apolipoprotein E4 potentiates amyloid beta peptide-induced lysosomal leakage and apoptosis in neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503910200

21 January 2018

Identifiers

DOI

10.1074/JBC.M503910200

1 reference

22 December 2017

PubMed ID

15890642

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22 December 2017