Interaction of presenilins with FKBP38 promotes apoptosis by reducing mitochondrial Bcl-2. (Q46499587)

22 December 2017

title

Interaction of presenilins with FKBP38 promotes apoptosis by reducing mitochondrial Bcl-2. (English)

1 reference

22 December 2017

author name string

Hua-Qin Wang

1

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22 December 2017

Yoshifumi Nakaya

2

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22 December 2017

Zhenyu Du

3

1 reference

22 December 2017

Takuya Yamane

4

1 reference

22 December 2017

Michiko Shirane

5

1 reference

22 December 2017

Takashi Kudo

6

1 reference

22 December 2017

Masatoshi Takeda

7

1 reference

22 December 2017

Koichi Takebayashi

8

1 reference

22 December 2017

Yoichi Noda

9

1 reference

22 December 2017

Keiichi I Nakayama

10

1 reference

22 December 2017

Masaki Nishimura

11

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22 December 2017

publication date

19 May 2005

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22 December 2017

published in

Human Molecular Genetics

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22 December 2017

volume

14

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22 December 2017

issue

13

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22 December 2017

page(s)

1889-1902

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22 December 2017

Mitochondria: releasing power for life and unleashing the machineries of death

cites work

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI195

The pathophysiology of mitochondrial cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI195

Cellular distribution of Bcl-2 family proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI195

Apoptosis in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI195

Mechanisms of neuronal degeneration in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI195

Interfering with apoptosis: Ca(2+)-binding protein ALG-2 and Alzheimer's disease gene ALG-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI195

Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI195

Regulation of apoptosis by presenilin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI195

Staurosporine-induced activation of caspase-3 is potentiated by presenilin 1 familial Alzheimer's disease mutations in human neuroglioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI195

Alzheimer's disease presenilin-1 exon 9 deletion and L250S mutations sensitize SH-SY5Y neuroblastoma cells to hyperosmotic stress-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI195

Wild-type and mutated presenilins 2 trigger p53-dependent apoptosis and down-regulate presenilin 1 expression in HEK293 human cells and in murine neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI195

Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI195

Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI195

Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI195

Isolation of a cDNA encoding a novel human FK506-binding protein homolog containing leucine zipper and tetratricopeptide repeat motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI195

muFKBP38: a novel murine immunophilin homolog differentially expressed in Schwannoma cells and central nervous system neurons in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI195

Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI195

Alzheimer presenilins in the nuclear membrane, interphase kinetochores, and centrosomes suggest a role in chromosome segregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI195

Aberrant induction of Par-4 is involved in apoptosis of hippocampal neurons in presenilin-1 M146V mutant knock-in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI195

A novel protein, RTN-XS, interacts with both Bcl-XL and Bcl-2 on endoplasmic reticulum and reduces their anti-apoptotic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI195

The C-terminal fragment of presenilin 2 triggers p53-mediated staurosporine-induced apoptosis, a function independent of the presenilinase-derived N-terminal counterpart

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI195

Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI195

Interaction with telencephalin and the amyloid precursor protein predicts a ring structure for presenilins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI195

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI195

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI195

APH-1 interacts with mature and immature forms of presenilins and nicastrin and may play a role in maturation of presenilin.nicastrin complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDI195

21 January 2018

Identifiers

DOI

10.1093/HMG/DDI195

1 reference

22 December 2017

release_3xehnt4dxjhmzg6tomh6hkubha

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/3xehnt4dxjhmzg6tomh6hkubha

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

15905180

1 reference

22 December 2017