Radiosensitization of cervical cancer cells via double-strand DNA break repair inhibition. (Q46511436)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18589211%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

title

Radiosensitization of cervical cancer cells via double-strand DNA break repair inhibition (English)

1 reference

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9 January 2020

main subject

cervix uterine cancer

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4

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9 January 2020

author name string

Christa B Fuhrman

1

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9 January 2020

Josh Kilgore

2

1 reference

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9 January 2020

Yvette D LaCoursiere

3

1 reference

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9 January 2020

Brett A Milash

5

1 reference

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9 January 2020

Andrew P Soisson

6

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9 January 2020

Karen A Zempolich

7

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9 January 2020

language of work or name

English

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publication date

1 July 2008

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9 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18589211%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

volume

110

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9 January 2020

issue

1

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9 January 2020

page(s)

93-98

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Focus on endometrial and cervical cancer

9 January 2020

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Phosphatidylinositol 3-kinase inhibition by LY294002 radiosensitizes human cervical cancer cell lines

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Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints

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ATM phosphorylates histone H2AX in response to DNA double-strand breaks

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DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

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