Induction of leukemia-specific CD8+ cytotoxic T cells with autologous myeloid leukemic cells maturated with a fiber-modified adenovirus encoding TNF-alpha (Q46516144)

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scientific article published on 20 January 2005

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English	Induction of leukemia-specific CD8+ cytotoxic T cells with autologous myeloid leukemic cells maturated with a fiber-modified adenovirus encoding TNF-alpha	scientific article published on 20 January 2005

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scholarly article

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/15922966

Induction of leukemia-specific CD8+ cytotoxic T cells with autologous myeloid leukemic cells maturated with a fiber-modified adenovirus encoding TNF-alpha (English)

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/15922966

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Aurore Saudemont

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/15922966

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Bruno Quesnel

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Selim Corm

2

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/15922966

Thomas Wickham

3

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/15922966

Dominique Hetuin

4

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/15922966

publication date

20 January 2005

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22 December 2017

http://europepmc.org/abstract/MED/15922966

Molecular Therapy

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22 December 2017

http://europepmc.org/abstract/MED/15922966

11

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/15922966

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/15922966

950-959

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Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/15922966

Dendritic cell-based immunotherapy for the treatment of hematological malignancies

1 reference

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Leukemic dendritic cells: potential for therapy and insights towards immune escape by leukemic blasts

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Circulating blood dendritic cells from myeloid leukemia patients display quantitative and cytogenetic abnormalities as well as functional impairment

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Human acute myeloblastic leukemia cells differentiate in vitro into mature dendritic cells and induce the differentiation of cytotoxic T cells against autologous leukemias

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7 January 2021

The generation of dendritic-like cells with increased allostimulatory function from acute myeloid leukemia cells of various FAB subclasses

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The efficient generation of CD83 positive immunocompetent dendritic cells from CD14 positive acute myelomonocytic or monocytic leukemia cells in vitro

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Stimulation of autologous proliferative and cytotoxic T-cell responses by "leukemic dendritic cells" derived from blast cells in acute myeloid leukemia

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Dendritic cells in acute promyelocytic leukaemia

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Leukemic dendritic cells generated in the presence of FLT3 ligand have the capacity to stimulate an autologous leukemia-specific cytotoxic T cell response from patients with acute myeloid leukemia

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Eliciting cytotoxic T lymphocytes against acute myeloid leukemia-derived antigens: evaluation of dendritic cell-leukemia cell hybrids and other antigen-loading strategies for dendritic cell-based vaccination

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Primary acute myeloid leukaemia blasts resistant to cytokine-induced differentiation to dendritic-like leukaemia cells can be forced to differentiate by the addition of bryostatin-1.

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Identification of CD14 as a predictor for leukemic dendritic cell differentiation in acute myeloid leukemia

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Efficient generation of antileukemic autologous T cells by short-term culture and gamma-irradiation of myeloid leukemic cells.

1 reference

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TNF-alpha receptor 1 expression on acute myeloid leukemic blasts predicts differentiation into leukemic dendritic cells

1 reference

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Human dendritic cell maturation by adenovirus transduction enhances tumor antigen-specific T-cell responses

1 reference

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7 January 2021

Adenovirus-induced maturation of dendritic cells through a PI3 kinase-mediated TNF-alpha induction pathway

1 reference

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Tumour necrosis factor-alpha (TNF-alpha) transgene-expressing dendritic cells (DCs) undergo augmented cellular maturation and induce more robust T-cell activation and anti-tumour immunity than DCs generated in recombinant TNF-alpha

1 reference

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Optimization of dendritic cell maturation and gene transfer by recombinant adenovirus

1 reference

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Adenovirus type 5 vectors induce dendritic cell differentiation in human CD14(+) monocytes cultured under serum-free conditions

1 reference

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7 January 2021

Increased gene transfer in acute myeloid leukemic cells by an adenovirus vector containing a modified fiber protein.

1 reference

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Adenovirus targeted to heparan-containing receptors increases its gene delivery efficiency to multiple cell types

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7 January 2021

Targeting adenovirus

1 reference

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Transduction of bone marrow cells by the AdZ.F(pK7) modified adenovirus demonstrates preferential gene transfer in myeloma cells.

1 reference

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Gamma-irradiation enhances transgene expression in leukemic cells

1 reference

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Short-term culture of myeloid leukemic cells allows efficient transduction by adenoviral vectors

1 reference

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Adenovirus-mediated CD40 ligand gene-engineered dendritic cells elicit enhanced CD8(+) cytotoxic T-cell activation and antitumor immunity

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Dendritic cells engineered to express the Flt3 ligand stimulate type I immune response, and induce enhanced cytoxic T and natural killer cell cytotoxicities and antitumor immunity

1 reference

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Rapamycin inhibits macropinocytosis and mannose receptor-mediated endocytosis by bone marrow-derived dendritic cells

1 reference

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Influence of immunosuppressive drugs on dendritic cells

1 reference

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Rapamycin inhibits IL-4--induced dendritic cell maturation in vitro and dendritic cell mobilization and function in vivo

1 reference

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Mechanistic insights into impaired dendritic cell function by rapamycin: inhibition of Jak2/Stat4 signaling pathway

1 reference

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Rapamycin specifically interferes with GM-CSF signaling in human dendritic cells, leading to apoptosis via increased p27KIP1 expression

1 reference

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Rapamycin induces apoptosis in monocyte- and CD34-derived dendritic cells but not in monocytes and macrophages

1 reference

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Rapamycin impairs antigen uptake of human dendritic cells

1 reference

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Extracellular signal-regulated protein kinase signaling pathway negatively regulates the phenotypic and functional maturation of monocyte-derived human dendritic cells.

1 reference

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The PI3 kinase, p38 SAP kinase, and NF-kappaB signal transduction pathways are involved in the survival and maturation of lipopolysaccharide-stimulated human monocyte-derived dendritic cells

1 reference

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T cells from the tumor microenvironment of patients with progressive myeloma can generate strong, tumor-specific cytolytic responses to autologous, tumor-loaded dendritic cells

1 reference

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7 January 2021

Identifiers

10.1016/J.YMTHE.2004.12.016

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/15922966

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 December 2017

http://europepmc.org/abstract/MED/15922966

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