Discovery of a potent, selective, and orally bioavailable c-Met inhibitor: 1-(2-hydroxy-2-methylpropyl)-N-(5-(7-methoxyquinolin-4-yloxy)pyridin-2-yl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide (AMG 458). (Q46540377)
Jump to navigation
Jump to search
scientific article published on 14 June 2008
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | Discovery of a potent, selective, and orally bioavailable c-Met inhibitor: 1-(2-hydroxy-2-methylpropyl)-N-(5-(7-methoxyquinolin-4-yloxy)pyridin-2-yl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide (AMG 458). |
scientific article published on 14 June 2008 |
Statements
Discovery of a potent, selective, and orally bioavailable c-Met inhibitor: 1-(2-hydroxy-2-methylpropyl)-N-(5-(7-methoxyquinolin-4-yloxy)pyridin-2-yl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide (AMG 458) (English)
Longbin Liu
Aaron Siegmund
Paula Kaplan-Lefko
Karen Rex
April Chen
Jasmine Lin
Jodi Moriguchi
Loren Berry
Liyue Huang
Yohannes Teffera
Yajing Yang
Yihong Zhang
Steven F Bellon
Matthew Lee
Roman Shimanovich
Annette Bak
Celia Dominguez
Mark H Norman
Jean-Christophe Harmange
Isabelle Dussault
Tae-Seong Kim