Atrophin 1 (Q4654745)

mammalian protein found in Homo sapiens

ATN1
atrophin-1
dentatorubral-pallidoluysian atrophy protein

Language	Label	Description	Also known as
English	Atrophin 1	mammalian protein found in Homo sapiens	ATN1 atrophin-1 dentatorubral-pallidoluysian atrophy protein

Statements

1 reference

13 November 2019

1 reference

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P54259

1 reference

13 November 2019

1 reference

13 November 2019

6 references

8 April 2019

Atrophin proteins interact with the Fat1 cadherin and regulate migration and orientation in vascular smooth muscle cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54259

8 April 2019

The interactome of the histone gene regulatory factor HiNF-P suggests novel cell cycle related roles in transcriptional control and RNA processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54259

8 April 2019

Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54259

8 April 2019

Atrophin-1, the dentato-rubral and pallido-luysian atrophy gene product, interacts with ETO/MTG8 in the nuclear matrix and represses transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54259

8 April 2019

Conserved beta-hairpin recognition by the GYF domains of Smy2 and GIGYF2 in mRNA surveillance and vesicular transport complexes

GOA

curator

Parkinsons Disease Gene Ontology Initiative

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54259

8 April 2019

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54259

determination method

IPI

transcription corepressor activity

1 reference

27 February 2018

Atrophin-1, the dentato-rubral and pallido-luysian atrophy gene product, interacts with ETO/MTG8 in the nuclear matrix and represses transcription

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54259&geneProductId=UniProtKB:P54259

determination method

IDA

protein domain specific binding

1 reference

8 April 2019

The Chediak-Higashi protein interacts with SNARE complex and signal transduction proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54259

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54259

determination method

IBA

transcription corepressor activity

1 reference

8 April 2019

Atrophin-1, the dentato-rubral and pallido-luysian atrophy gene product, interacts with ETO/MTG8 in the nuclear matrix and represses transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54259

determination method

IDA

perinuclear region of cytoplasm

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54259

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54259

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54259

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54259

8 April 2019

Cleavage of atrophin-1 at caspase site aspartic acid 109 modulates cytotoxicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54259

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54259

determination method

IBA

biological process

neuron apoptotic process

1 reference

8 April 2019

Cleavage of atrophin-1 at caspase site aspartic acid 109 modulates cytotoxicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54259

determination method

IDA

central nervous system development

1 reference

8 April 2019

Abnormal gene product identified in hereditary dentatorubral–pallidoluysian atrophy (DRPLA) brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54259

determination method

TAS

regulation of transcription, DNA-templated

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54259&geneProductId=UniProtKB:P54259

determination method

IEA

negative regulation of transcription by RNA polymerase II

1 reference

8 April 2019

Atrophin-1, the dentato-rubral and pallido-luysian atrophy gene product, interacts with ETO/MTG8 in the nuclear matrix and represses transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P54259

determination method

IDA

transcription, DNA-templated

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P54259&geneProductId=UniProtKB:P54259

determination method

IEA

Gene Atlas image

PBB GE ATN1 40489 at fs.png
732 × 530; 11 KB

0 references

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

Atrophin 1 (Q4654745)

Statements

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Atrophin 1 (Q4654745)

Statements

Identifiers

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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