Pembrolizumab in advanced soft-tissue sarcoma and bone sarcoma (SARC028): a multicentre, two-cohort, single-arm, open-label, phase 2 trial (Q46559484)

23 December 2017

http://europepmc.org/abstract/MED/28988646

title

Pembrolizumab in advanced soft-tissue sarcoma and bone sarcoma (SARC028): a multicentre, two-cohort, single-arm, open-label, phase 2 trial (English)

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23 December 2017

http://europepmc.org/abstract/MED/28988646

main subject

phase II clinical trial

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multicenter clinical trial

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1 reference

14

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2 June 2020

Ruth Salazar

17

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2 June 2020

Alexander J. Lazar

19

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2 June 2020

Robert G. Maki

22

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2 June 2020

6

James Hu

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2 June 2020

20

Ignacio I Wistuba

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2 June 2020

7

Sandra D'Angelo

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2 June 2020

author name string

Hussein A Tawbi

1

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2 June 2020

Melissa Burgess

2

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2 June 2020

Vanessa Bolejack

3

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2 June 2020

Brian A Van Tine

4

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2 June 2020

Scott M Schuetze

5

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2 June 2020

Steven Attia

8

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2 June 2020

Richard F Riedel

9

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2 June 2020

Dennis A Priebat

10

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2 June 2020

Sujana Movva

11

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2 June 2020

Lara E Davis

12

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2 June 2020

Scott H Okuno

13

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2 June 2020

John Crowley

15

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2 June 2020

Lisa H Butterfield

16

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2 June 2020

Jaime Rodriguez-Canales

18

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2 June 2020

Laurence H Baker

21

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2 June 2020

Denise Reinke

23

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2 June 2020

Shreyaskumar Patel

24

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2 June 2020

publication date

4 October 2017

1 reference

23 December 2017

http://europepmc.org/abstract/MED/28988646

published in

Lancet Oncology Commission

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2 June 2020

volume

18

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2 June 2020

issue

11

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2 June 2020

page(s)

1493-1501

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Patterns of care and outcomes of patients with METAstatic soft tissue SARComa in a real-life setting: the METASARC observational study

2 June 2020

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Eribulin versus dacarbazine in previously treated patients with advanced liposarcoma or leiomyosarcoma: a randomised, open-label, multicentre, phase 3 trial.

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7 January 2021

Olaratumab and doxorubicin versus doxorubicin alone for treatment of soft-tissue sarcoma: an open-label phase 1b and randomised phase 2 trial

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7 January 2021

Pazopanib for metastatic soft-tissue sarcoma (PALETTE): a randomised, double-blind, placebo-controlled phase 3 trial

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7 January 2021

Addition of muramyl tripeptide to chemotherapy for patients with newly diagnosed metastatic osteosarcoma: a report from the Children's Oncology Group

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7 January 2021

Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial

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7 January 2021

Safety and activity of pembrolizumab in patients with locally advanced or metastatic urothelial cancer (KEYNOTE-012): a non-randomised, open-label, phase 1b study

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PD-1 Blockade with Pembrolizumab in Advanced Merkel-Cell Carcinoma.

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Phase II Study of the Efficacy and Safety of Pembrolizumab for Relapsed/Refractory Classic Hodgkin Lymphoma

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7 January 2021

Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma

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7 January 2021

Experience with the use of high-dose interleukin-2 in the treatment of 652 cancer patients

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Methotrexate, Doxorubicin, and Cisplatin (MAP) Plus Maintenance Pegylated Interferon Alfa-2b Versus MAP Alone in Patients With Resectable High-Grade Osteosarcoma and Good Histologic Response to Preoperative MAP: First Results of the EURAMOS-1 Good R

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7 January 2021

Progression-free rate as the principal end-point for phase II trials in soft-tissue sarcomas

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7 January 2021

Nonparametric Estimation from Incomplete Observations

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Prevalence of tumor-infiltrating lymphocytes and PD-L1 expression in the soft tissue sarcoma microenvironment

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7 January 2021

Tumor infiltrating PD1-positive lymphocytes and the expression of PD-L1 predict poor prognosis of soft tissue sarcomas

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The Next Hurdle in Cancer Immunotherapy: Overcoming the Non-T-Cell-Inflamed Tumor Microenvironment

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PDL1 expression is a poor-prognosis factor in soft-tissue sarcomas.

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7 January 2021

Immunotherapy with single agent nivolumab for advanced leiomyosarcoma of the uterus: Results of a phase 2 study.

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7 January 2021

Loss of PTEN Is Associated with Resistance to Anti-PD-1 Checkpoint Blockade Therapy in Metastatic Uterine Leiomyosarcoma.

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7 January 2021

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Identifiers

DOI

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2 June 2020

1 reference