Hypermethylation of hepatic Gck promoter in ageing rats contributes to diabetogenic potential (Q46581862)

23 December 2017

title

Hypermethylation of hepatic Gck promoter in ageing rats contributes to diabetogenic potential (English)

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23 December 2017

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M H Jiang

1

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23 December 2017

J Fei

2

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23 December 2017

M S Lan

3

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23 December 2017

Z P Lu

4

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23 December 2017

M Liu

5

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23 December 2017

W W Fan

6

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23 December 2017

X Gao

7

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23 December 2017

D R Lu

8

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23 December 2017

publication date

22 May 2008

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23 December 2017

published in

Diabetologia

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23 December 2017

volume

51

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23 December 2017

issue

8

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23 December 2017

page(s)

1525-1533

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23 December 2017

https://scigraph.springernature.com/pub.10.1007/s00125-008-1034-8

exact match

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cites work

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Identification of valid housekeeping genes and antioxidant enzyme gene expression change in the aging rat liver

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Phosphorylation of glucose in isolated rat hepatocytes. Sigmoidal kinetics explained by the activity of glucokinase alone

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Site-specific methylation of the rat prolactin and growth hormone promoters correlates with gene expression

21 January 2018

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Extensive DNA methylation spanning the Rb promoter in retinoblastoma tumors

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Microdetermination of glycogen with anthrone reagent

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12 December 2020

Stimulation by insulin of glucokinase gene transcription in liver of diabetic rats

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An Age-dependent Modification of Enzyme Regulation

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Characterization of regulatory elements and methylation pattern of the autoimmune regulator (AIRE) promoter

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Impact of Insulin Resistance on Risk of Type 2 Diabetes and Cardiovascular Disease in People With Metabolic Syndrome

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Evidence for a role of glucose-induced translocation of glucokinase in the control of hepatic glycogen synthesis

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Regulation of phosphoenolpyruvate carboxykinase (GTP) synthesis in rat liver cells. Rapid induction of specific mRNA by glucagon or cyclic AMP and permissive effect of dexamethasone

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Differential expression and regulation of the glucokinase gene in liver and islets of Langerhans

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12 December 2020

An alternate promoter in the glucokinase gene is active in the pancreatic beta cell.

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12 December 2020

Factors underlying significant underestimations of glucokinase activity in crude liver extracts: physiological implications of higher cellular activity.

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The effect of aging on carbohydrate metabolism: A review of the English literature and a practical approach to the diagnosis of diabetes mellitus in the elderly

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Glucose 6-Phosphate Produced by Glucokinase, but Not Hexokinase I, Promotes the Activation of Hepatic Glycogen Synthase

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12 December 2020

Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitus

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12 December 2020

Insulin resistance and insulin deficiency in the pathogenesis of type 2 (non-insulin-dependent) diabetes mellitus: errors of metabolism or of methods?

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12 December 2020

Effect of 5-azacytidine and congeners on DNA methylation and expression of deoxycytidine kinase in the human lymphoid cell lines CCRF/CEM/0 and CCRF/CEM/dCk-1.

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12 December 2020

Detailed methylation analysis of the glutathione S-transferase pi (GSTP1) gene in prostate cancer

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12 December 2020

INSULIN-DEPENDENT SYNTHESIS OF LIVER GLUCOKINASE IN THE RAT

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12 December 2020

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

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12 December 2020

Increased potency and efficacy of combined phosphorylase inactivation and glucokinase activation in control of hepatocyte glycogen metabolism

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12 December 2020

Correction of diabetic alterations by glucokinase.

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Liver glucokinase: decreased activity in patients with type II diabetes

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Insulin resistance, beta-cell function, and glucose tolerance in Brazilian adolescents with obesity or risk factors for type 2 diabetes mellitus.

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12 December 2020

Glucose 6-phosphate produced by gluconeogenesis and by glucokinase is equally effective in activating hepatic glycogen synthase

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12 December 2020

Missense glucokinase mutation in maturity-onset diabetes of the young and mutation screening in late-onset diabetes

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12 December 2020

Glucose administration induces the premature expression of liver glucokinase gene in newborn rats. Relation with DNase-I-hypersensitive sites

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12 December 2020

Aging, adiposity, and calorie restriction

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12 December 2020

The role of glucose 6-phosphate in mediating the effects of glucokinase overexpression on hepatic glucose metabolism

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12 December 2020

10.1007/S00125-008-1034-8

Identifiers

DOI

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23 December 2017

PubMed ID

18496667

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23 December 2017