PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP. (Q46592766)

23 December 2017

title

PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP. (English)

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23 December 2017

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6

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23 December 2017

Almut Schulze

object named as

Almut Schulze

7

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author name string

Thomas Porstmann

1

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23 December 2017

Beatrice Griffiths

2

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23 December 2017

Yuen-Li Chung

3

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23 December 2017

Oona Delpuech

4

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23 December 2017

John R Griffiths

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23 December 2017

language of work or name

English

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publication date

1 September 2005

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23 December 2017

published in

Oncogene

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23 December 2017

volume

24

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23 December 2017

issue

43

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23 December 2017

page(s)

6465-6481

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23 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1208802

exact match

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cites work

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Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER

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SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1208802

1 reference

23 December 2017

PubMed ID

16007182

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23 December 2017