The lysyl oxidase inhibitor (β-aminopropionitrile) reduces leptin profibrotic effects and ameliorates cardiovascular remodeling in diet-induced obesity in rats. (Q46609201)

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scientific article published on 15 January 2016

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English	The lysyl oxidase inhibitor (β-aminopropionitrile) reduces leptin profibrotic effects and ameliorates cardiovascular remodeling in diet-induced obesity in rats.	scientific article published on 15 January 2016

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The lysyl oxidase inhibitor (β-aminopropionitrile) reduces leptin profibrotic effects and ameliorates cardiovascular remodeling in diet-induced obesity in rats (English)

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Ernesto Martinez-Martinez

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Victoria Cachofeiro

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Cristina Rodríguez

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Raquel Jurado-López

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José Martínez-González

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María Miana

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María Visitación Bartolomé

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María Luaces

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Fabián Islas

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Natalia López-Andrés

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15 January 2016

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Journal of Molecular and Cellular Cardiology

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96-104

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National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participants

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Regulation of lysyl oxidase in vascular cells: lysyl oxidase as a new player in cardiovascular diseases.

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Lysyl oxidase as a potential therapeutic target

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Low density lipoproteins downregulate lysyl oxidase in vascular endothelial cells and the arterial wall.

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Intracellular lysyl oxidase: effect of a specific inhibitor on nuclear mass in proliferating cells

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The lysyl oxidase inhibitor β-aminopropionitrile reduces body weight gain and improves the metabolic profile in diet-induced obesity in rats

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Lysyl oxidase expression and collagen cross-linking during chronic adriamycin nephropathy

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Upregulation of lysyl oxidase and MMPs during cardiac remodeling in human dilated cardiomyopathy

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Lysyl oxidase deficiency: a new cause of human arterial dissection

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Paradoxical roles for lysyl oxidases in cancer--a prospect

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Leptin induces cardiac fibrosis through galectin-3, mTOR and oxidative stress

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Comparative sensitivities of purified preparations of lysyl oxidase and other amine oxidases to active site-directed enzyme inhibitors

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Obesity, metabolic dysfunction, and cardiac fibrosis: pathophysiological pathways, molecular mechanisms, and therapeutic opportunities

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Lysyl oxidase (LOX) in vascular remodelling

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Myocardial lysyl oxidase regulation of cardiac remodeling in a murine model of diet-induced metabolic syndrome

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Collagen cross-linking but not collagen amount associates with elevated filling pressures in hypertensive patients with stage C heart failure: potential role of lysyl oxidase.

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Inactivation of the lysyl oxidase gene Lox leads to aortic aneurysms, cardiovascular dysfunction, and perinatal death in mice

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10.1016/J.YJMCC.2016.01.012

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