HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response. (Q46625510)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18438399%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

title

HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response (English)

1 reference

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6 January 2020

2

1 reference

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6 January 2020

Juan A. Bernal

series ordinal

3

1 reference

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6 January 2020

author name string

Nabieh Ayoub

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18438399%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Ashok R Venkitaraman

series ordinal

4

1 reference

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6 January 2020

language of work or name

English

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publication date

27 April 2008

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6 January 2020

number of pages

5

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inferred from page(s)

published in

Nature

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6 January 2020

volume

453

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6 January 2020

issue

7195

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6 January 2020

page(s)

682-686

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https://scigraph.springernature.com/pub.10.1038/nature06875

6 January 2020

exact match

0 references

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High- and low-mobility populations of HP1 in heterochromatin of mammalian cells

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Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage

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Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks

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Phosphorylation of heterochromatin protein 1 by casein kinase II is required for efficient heterochromatin binding in Drosophila.

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Phosphorylation site mutations in heterochromatin protein 1 (HP1) reduce or eliminate silencing activity

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Structure of HP1 chromodomain bound to a lysine 9-methylated histone H3 tail

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Phosphorylation stabilizes alternatively spliced CD44 mRNA transcripts in breast cancer cells: inhibition by antisense complementary to casein kinase II mRNA

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DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

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7 January 2021

Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway

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7 January 2021

Heterochromatin is refractory to gamma-H2AX modification in yeast and mammals

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gammaH2AX foci form preferentially in euchromatin after ionising-radiation.

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ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

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7 January 2021

Evidence for the existence of an HP1-mediated subcode within the histone code.

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PML bodies control the nuclear dynamics and function of the CHFR mitotic checkpoint protein

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