Exotoxin A-eEF2 complex structure indicates ADP ribosylation by ribosome mimicry (Q46656627)

24 December 2017

title

Exotoxin A-eEF2 complex structure indicates ADP ribosylation by ribosome mimicry (English)

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24 December 2017

author

René Jørgensen

1

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24 December 2017

author name string

A Rod Merrill

2

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24 December 2017

Susan P Yates

3

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24 December 2017

Victor E Marquez

4

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24 December 2017

Adrian L Schwan

5

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24 December 2017

Thomas Boesen

6

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24 December 2017

Gregers R Andersen

7

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24 December 2017

language of work or name

English

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publication date

1 August 2005

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24 December 2017

published in

Nature

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24 December 2017

volume

436

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24 December 2017

issue

7053

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24 December 2017

page(s)

979-984

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24 December 2017

https://scigraph.springernature.com/pub.10.1038/nature03871

exact match

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cites work

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Crystal structure of the catalytic domain of Pseudomonas exotoxin A complexed with a nicotinamide adenine dinucleotide analog: implications for the activation process and for ADP ribosylation

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7 January 2021

Structure of the isolated catalytic domain of diphtheria toxin

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7 January 2021

Crystal structure of diphtheria toxin bound to nicotinamide adenine dinucleotide

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7 January 2021

Unusual conformation of nicotinamide adenine dinucleotide (NAD) bound to diphtheria toxin: a comparison with NAD bound to the oxidoreductase enzymes

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7 January 2021

Crystal structure and novel recognition motif of rho ADP-ribosylating C3 exoenzyme from Clostridium botulinum: structural insights for recognition specificity and catalysis

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7 January 2021

NAD binding induces conformational changes in Rho ADP-ribosylating clostridium botulinum C3 exoenzyme

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7 January 2021

The crystal structure of C3stau2 from Staphylococcus aureus and its complex with NAD

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Evolution and mechanism from structures of an ADP-ribosylating toxin and NAD complex

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Establishment of Pseudomonas aeruginosa infection: lessons from a versatile opportunist

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Diphtheria remains a threat to health in the developing world--an overview

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Understanding the mode of action of diphtheria toxin: a perspective on progress during the 20th century

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Investigation into the catalytic role for the tryptophan residues within domain III of Pseudomonas aeruginosa exotoxin A.

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Inhibitors of ADP-ribosylating bacterial toxins based on oxacarbenium ion character at their transition states

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Thiazole-4-carboxamide adenine dinucleotide (TAD). Analogues stable to phosphodiesterase hydrolysis

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Structure-function analysis of water-soluble inhibitors of the catalytic domain of exotoxin A from Pseudomonas aeruginosa

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Two crystal structures demonstrate large conformational changes in the eukaryotic ribosomal translocase

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7 January 2021

Characterization of oxidized nicotinamide adenine dinucleotide (NAD(+)) analogues using a high-pressure-liquid-chromatography-based NAD(+)-glycohydrolase assay and comparison with fluorescence-based measurements

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Exotoxin A of Pseudomonas aeruginosa: substitution of glutamic acid 553 with aspartic acid drastically reduces toxicity and enzymatic activity

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Pseudomonas aeruginosa exotoxin A: effects of mutating tyrosine-470 and tyrosine-481 to phenylalanine

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Crystal structure of ADP-ribosylated ribosomal translocase from Saccharomyces cerevisiae

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Transition state structure for ADP-ribosylation of eukaryotic elongation factor 2 catalyzed by diphtheria toxin

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Retroviral insertional mutagenesis identifies a small protein required for synthesis of diphthamide, the target of bacterial ADP-ribosylating toxins

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A catalytic loop within Pseudomonas aeruginosa exotoxin A modulates its transferase activity

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Functional aspects of protein mono-ADP-ribosylation

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Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation

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7 January 2021

Recognition of cognate transfer RNA by the 30S ribosomal subunit

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7 January 2021

Purification and crystallization of the yeast elongation factor eEF2.

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7 January 2021

Insight into the catalytic mechanism of Pseudomonas aeruginosa exotoxin A. Studies of toxin interaction with eukaryotic elongation factor-2.

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An approach to multi-copy search in molecular replacement

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Improved methods for building protein models in electron density maps and the location of errors in these models

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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7 January 2021

Identifiers

DOI

10.1038/NATURE03871

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24 December 2017

Dimensions Publication ID

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24 December 2017