LOX-1 receptor blockade abrogates oxLDL-induced oxidative DNA damage and prevents activation of the transcriptional repressor Oct-1 in human coronary arterial endothelium (Q46662739)

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English	LOX-1 receptor blockade abrogates oxLDL-induced oxidative DNA damage and prevents activation of the transcriptional repressor Oct-1 in human coronary arterial endothelium	scientific article

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scholarly article

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/18390905

LOX-1 receptor blockade abrogates oxLDL-induced oxidative DNA damage and prevents activation of the transcriptional repressor Oct-1 in human coronary arterial endothelium (English)

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/18390905

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24 December 2017

http://europepmc.org/abstract/MED/18390905

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Jürgen Borlak

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Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/18390905

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7 April 2008

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Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/18390905

Journal of Biological Chemistry

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Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/18390905

283

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Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/18390905

28

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24 December 2017

http://europepmc.org/abstract/MED/18390905

19456-19464

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Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/18390905

Diagnostic implications of circulating oxidized low density lipoprotein levels as a biochemical risk marker of coronary artery disease

1 reference

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Expression of lectinlike oxidized low-density lipoprotein receptor-1 in human atherosclerotic lesions

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Overexpression of lectin-like oxidized low-density lipoprotein receptor-1 induces intramyocardial vasculopathy in apolipoprotein E-null mice

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Deletion of LOX-1 reduces atherogenesis in LDLR knockout mice fed high cholesterol diet

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In vivo and in vitro studies support that a new splicing isoform of OLR1 gene is protective against acute myocardial infarction

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An endothelial receptor for oxidized low-density lipoprotein

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Role of caspases in Ox-LDL-induced apoptotic cascade in human coronary artery endothelial cells

1 reference

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21 January 2018

Oxidative Decay of DNA

1 reference

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Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress

1 reference

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21 January 2018

Oxidative DNA damage and cardiovascular disease

1 reference

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Immunological response to oxidized LDL occurs in association with oxidative DNA damage independently of serum LDL concentrations in dyslipidemic patients

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Counteraction by MutT protein of transcriptional errors caused by oxidative damage.

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Elevated levels of oxidative DNA damage and DNA repair enzymes in human atherosclerotic plaques

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The role of oxidative stress in carcinogenesis

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Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) transcriptional regulation by Oct-1 in human endothelial cells: implications for atherosclerosis

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21 January 2018

Octamer-dependent in vivo expression of the endothelial cell-specific TIE2 gene

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Multiple octamer binding sites in the promoter region of the bovine alpha s2-casein gene

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The core promoter of human thioredoxin reductase 1: cloning, transcriptional activity, and Oct-1, Sp1, and Sp3 binding reveal a housekeeping-type promoter for the AU-rich element-regulated gene.

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The virtuoso of versatility: POU proteins that flex to fit

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S phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key component

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Cytochrome P450 epoxygenases as EDHF synthase(s).

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Gene expression in distinct regions of the heart

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Mildly oxidised LDL induces more macrophage death than moderately oxidised LDL: roles of peroxidation, lipoprotein-associated phospholipase A2 and PPARgamma.

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21 January 2018

Oxidized LDL and malondialdehyde-modified LDL in patients with acute coronary syndromes and stable coronary artery disease.

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Involvement of the MAP kinase pathways in induction of GADD45 following UV radiation.

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Validation of endogenous controls for gene expression analysis in microdissected human renal biopsies

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Interleukin-6-induced tethering of STAT3 to the LAP/C/EBPbeta promoter suggests a new mechanism of transcriptional regulation by STAT3.

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Measurement of protein using bicinchoninic acid

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Age-dependent impairment of endothelial progenitor cells is corrected by growth-hormone-mediated increase of insulin-like growth-factor-1.

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21 January 2018

Oxidized LDL through LOX-1 modulates LDL-receptor expression in human coronary artery endothelial cells

1 reference

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21 January 2018

Ligand specificity of LOX-1, a novel endothelial receptor for oxidized low density lipoprotein

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DNA damage as a new emerging risk factor in atherosclerosis.

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Modulation of base excision repair by low density lipoprotein, oxidized low density lipoprotein and antioxidants in mouse monocytes

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21 January 2018

Lipid lowering reduces oxidative stress and endothelial cell activation in rabbit atheroma

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21 January 2018

Oxidized LDL induces mitochondrially associated reactive oxygen/nitrogen species formation in endothelial cells

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Characterization of the stress-inducing effects of homocysteine

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Early molecular changes in irradiated aortic endothelium

1 reference

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Molecular mechanism of endothelial growth arrest by laminar shear stress

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21 January 2018

LOX-1 mediates oxidized low-density lipoprotein-induced expression of matrix metalloproteinases in human coronary artery endothelial cells

1 reference

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21 January 2018

The octamer binding transcription factor Oct-1 is a stress sensor

1 reference

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Timp3 deficiency in insulin receptor-haploinsufficient mice promotes diabetes and vascular inflammation via increased TNF-alpha

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Gas6 inhibits apoptosis in vascular smooth muscle: role of Axl kinase and Akt

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Role of the growth arrest-specific gene 6 (gas6) product in thrombus stabilization

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Peroxiredoxin 2 functions as a noncatalytic scavenger of low-level hydrogen peroxide in the erythrocyte

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Peroxiredoxin 2 overexpression protects cortical neuronal cultures from ischemic and oxidative injury but not glutamate excitotoxicity, whereas Cu/Zn superoxide dismutase 1 overexpression protects only against oxidative injury

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Pioglitazone inhibits LOX-1 expression in human coronary artery endothelial cells by reducing intracellular superoxide radical generation

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B-cell-specif ic coactivator OBF-1/OCA-B/Bob1 required for immune response and germinal centre formation

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Identifiers

10.1074/JBC.M708309200

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/18390905

1 reference

Europe PubMed Central

24 December 2017

http://europepmc.org/abstract/MED/18390905

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