Statin treatment of adult human glial progenitors induces PPAR gamma-mediated oligodendrocytic differentiation (Q46668731)

24 December 2017

title

Statin treatment of adult human glial progenitors induces PPAR gamma-mediated oligodendrocytic differentiation (English)

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24 December 2017

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Fraser J Sim

1

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24 December 2017

Jennifer K Lang

2

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24 December 2017

Tracy A Ali

3

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24 December 2017

Neeta S Roy

4

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24 December 2017

G Edward Vates

5

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24 December 2017

Webster H Pilcher

6

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24 December 2017

Steven A Goldman

7

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24 December 2017

publication date

1 July 2008

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24 December 2017

published in

Glia

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24 December 2017

volume

56

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24 December 2017

issue

9

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24 December 2017

page(s)

954-962

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24 December 2017

Effects of treatment with simvastatin and pravastatin on cognitive function in patients with hypercholesterolaemia

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https://api.crossref.org/works/10.1002%2FGLIA.20669

Pre-oligodendrocytes from adult human CNS

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7 January 2021

Time right for statin trials in multiple sclerosis

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Trends in serum lipids and lipoproteins of adults, 1960-2002.

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7 January 2021

Lovastatin induces apoptosis of spontaneously immortalized rat brain neuroblasts: involvement of nonsterol isoprenoid biosynthesis inhibition

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https://api.crossref.org/works/10.1002%2FGLIA.20669

7 January 2021

Conceptual foundations of the UCSD Statin Study: a randomized controlled trial assessing the impact of statins on cognition, behavior, and biochemistry

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https://api.crossref.org/works/10.1002%2FGLIA.20669

7 January 2021

Lipophilic HMG-CoA reductase inhibitor has an anti-inflammatory effect: reduction of MRNA levels for interleukin-1beta, interleukin-6, cyclooxygenase-2, and p22phox by regulation of peroxisome proliferator-activated receptor alpha (PPARalpha) in pri

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7 January 2021

Chronic administration of statins alters multiple gene expression patterns in mouse cerebral cortex

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https://api.crossref.org/works/10.1002%2FGLIA.20669

7 January 2021

In vitro neuronal production and differentiation by precursor cells derived from the adult human forebrain

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https://api.crossref.org/works/10.1002%2FGLIA.20669

7 January 2021

Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain

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7 January 2021

Functional consequences of cysteine modification in the ligand binding sites of peroxisome proliferator activated receptors by GW9662.

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7 January 2021

Insig-1 "brakes" lipogenesis in adipocytes and inhibits differentiation of preadipocytes

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https://api.crossref.org/works/10.1002%2FGLIA.20669

7 January 2021

Simvastatin regulates oligodendroglial process dynamics and survival.

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https://api.crossref.org/works/10.1002%2FGLIA.20669

7 January 2021

Randomized trial of the effects of simvastatin on cognitive functioning in hypercholesterolemic adults

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https://api.crossref.org/works/10.1002%2FGLIA.20669

7 January 2021

Uptake of rosuvastatin by isolated rat hepatocytes: comparison with pravastatin

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20669

7 January 2021

Identification and isolation of multipotential neural progenitor cells from the subcortical white matter of the adult human brain

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20669

7 January 2021

HMG-CoA reductase inhibitor augments survival and differentiation of oligodendrocyte progenitors in animal model of multiple sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20669

7 January 2021

Regulation of gene expression associated with acute experimental autoimmune encephalomyelitis by Lovastatin

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20669

7 January 2021

The 3-hydroxy-3-methylglutaryl co-enzyme A reductase inhibitor pravastatin enhances neurite outgrowth in hippocampal neurons.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20669

7 January 2021

Clinical pharmacokinetics of pravastatin

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https://api.crossref.org/works/10.1002%2FGLIA.20669

7 January 2021

PPAR γ activators induce growth arrest and process extension in B12 oligodendrocyte‐like cells and terminal differentiation of cultured oligodendrocytes

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https://api.crossref.org/works/10.1002%2FGLIA.20669

7 January 2021

Identification, isolation, and promoter-defined separation of mitotic oligodendrocyte progenitor cells from the adult human subcortical white matter

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https://api.crossref.org/works/10.1002%2FGLIA.20669

7 January 2021

Statins upregulate CD36 expression in human monocytes, an effect strengthened when combined with PPAR-gamma ligands Putative contribution of Rho GTPases in statin-induced CD36 expression

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https://api.crossref.org/works/10.1002%2FGLIA.20669

7 January 2021

In vivo and in vitro blood-brain barrier transport of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20669

7 January 2021

PPAR delta agonists stimulate oligodendrocyte differentiation in tissue culture.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20669

7 January 2021

Complementary patterns of gene expression by human oligodendrocyte progenitors and their environment predict determinants of progenitor maintenance and differentiation.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20669

7 January 2021

Amelioration of experimental allergic encephalomyelitis in Lewis rats by lovastatin

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20669

7 January 2021

Evidence for a role of human organic anion transporters in the muscular side effects of HMG-CoA reductase inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20669

7 January 2021

Brain cholesterol synthesis in mice is affected by high dose of simvastatin but not of pravastatin

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20669

7 January 2021

Oral simvastatin treatment in relapsing-remitting multiple sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20669

7 January 2021

Statin-associated memory loss: analysis of 60 case reports and review of the literature

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20669

7 January 2021

Peroxisome proliferator-activated receptor gamma ligands inhibit Rho/Rho kinase pathway by inducing protein tyrosine phosphatase SHP-2.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20669

7 January 2021

Drug Insight: using statins to treat neuroinflammatory disease

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https://api.crossref.org/works/10.1002%2FGLIA.20669

7 January 2021

Fetal and adult human oligodendrocyte progenitor cell isolates myelinate the congenitally dysmyelinated brain

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20669

7 January 2021

The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20669

7 January 2021

Identifiers

DOI

10.1002/GLIA.20669

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24 December 2017

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24 December 2017