Metabolic and endothelial effects of trimetazidine on forearm skeletal muscle in patients with type 2 diabetes and ischemic cardiomyopathy (Q46713286)

24 December 2017

title

Metabolic and endothelial effects of trimetazidine on forearm skeletal muscle in patients with type 2 diabetes and ischemic cardiomyopathy (English)

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24 December 2017

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Lucilla D Monti

1

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24 December 2017

Emanuela Setola

2

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Gabriele Fragasso

3

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Riccardo P Camisasca

4

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Pietro Lucotti

5

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Elena Galluccio

6

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Anna Origgi

7

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Alberto Margonato

8

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PierMarco Piatti

9

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publication date

20 September 2005

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24 December 2017

American Journal of Physiology - Endocrinology and Metabolism

published in

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24 December 2017

volume

290

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issue

1

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24 December 2017

page(s)

E54-E59

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24 December 2017

Increased activity of endogenous endothelin in patients with type II diabetes mellitus

cites work

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

Insulin stimulates both endothelin and nitric oxide activity in the human forearm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

Malonyl coenzyme a decarboxylase inhibition protects the ischemic heart by inhibiting fatty acid oxidation and stimulating glucose oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

Effects of trimetazidine on myocardial perfusion and the contractile response of chronically dysfunctional myocardium in ischemic cardiomyopathy: a 24-month study

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

Physiological concentrations of insulin induce endothelin-mediated vasoconstriction during inhibition of NOS or PI3-kinase in skeletal muscle arterioles

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

Nitric oxide stimulates skeletal muscle glucose transport through a calcium/contraction- and phosphatidylinositol-3-kinase-independent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

Some biochemical aspects of the protective effect of trimetazidine on rat cardiomyocytes during hypoxia and reoxygenation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

Glycoprotein IIb/IIIa inhibitors in patients with unstable angina/non-ST–segment elevation myocardial infarction: Appropriate interpretation of the guidelines

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

Role of free fatty acids and insulin in determining free fatty acid and lipid oxidation in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

FATP1 channels exogenous FA into 1,2,3-triacyl-sn-glycerol and down-regulates sphingomyelin and cholesterol metabolism in growing 293 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

Metabolic manipulation in ischaemic heart disease, a novel approach to treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

Beneficial effects of trimetazidine in ex vivo working ischemic hearts are due to a stimulation of glucose oxidation secondary to inhibition of long-chain 3-ketoacyl coenzyme a thiolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

Myocardial insulin resistance associated with chronic hypertriglyceridemia and increased FFA levels in Type 2 diabetic patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

Association of insulin resistance, hyperleptinemia, and impaired nitric oxide release with in-stent restenosis in patients undergoing coronary stenting

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

Long-term oral L-arginine administration improves peripheral and hepatic insulin sensitivity in type 2 diabetic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

Acute intravenous L-arginine infusion decreases endothelin-1 levels and improves endothelial function in patients with angina pectoris and normal coronary arteriograms: correlation with asymmetric dimethylarginine levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

Banting lecture 1988. Role of insulin resistance in human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

Regulation of myocardial carbohydrate metabolism under normal and ischaemic conditions. Potential for pharmacological interventions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

Metabolic therapy in the treatment of ischaemic heart disease: the pharmacology of trimetazidine

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

Vascular function, insulin resistance and fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

Insulin increases cyclic nucleotide content in human vascular smooth muscle cells: a mechanism potentially involved in insulin-induced modulation of vascular tone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

Trimetazidine improves left ventricular function and quality of life in elderly patients with coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

Chronic endothelin-1 treatment leads to insulin resistance in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

Nitric oxide stimulates glucose transport and metabolism in rat skeletal muscle in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

Adaptation and maladaptation of the heart in diabetes: Part II: potential mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

Insulin-stimulated cyclic guanosine monophosphate inhibits vascular smooth muscle cell migration by inhibiting Ca/calmodulin-dependent protein kinase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00083.2005

10.1152/AJPENDO.00083.2005

21 January 2018

Identifiers

DOI

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24 December 2017

PubMed ID

16174656

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24 December 2017