Cloning and characterization of the rat free fatty acid receptor GPR120: in vivo effect of the natural ligand on GLP-1 secretion and proliferation of pancreatic beta cells. (Q46718654)

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scientific article published on 5 March 2008

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English	Cloning and characterization of the rat free fatty acid receptor GPR120: in vivo effect of the natural ligand on GLP-1 secretion and proliferation of pancreatic beta cells.	scientific article published on 5 March 2008

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scholarly article

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3 January 2020

Cloning and characterization of the rat free fatty acid receptor GPR120: in vivo effect of the natural ligand on GLP-1 secretion and proliferation of pancreatic beta cells (English)

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3 January 2020

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Taka-aki Koshimizu

4

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3 January 2020

3

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3 January 2020

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Toshiki Tanaka

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3 January 2020

Takeaki Yano

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3 January 2020

Akira Hirasawa

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3 January 2020

Gozoh Tsujimoto

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3 January 2020

publication date

5 March 2008

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3 January 2020

Naunyn-Schmiedeberg's Archives of Pharmacology

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3 January 2020

377

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3 January 2020

4-6

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3 January 2020

515-522

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3 January 2020

Stereospecific effects of fatty acids on proglucagon-derived peptide secretion in fetal rat intestinal cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

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Role of GPR40 in fatty acid action on the beta cell line INS-1E.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

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Therapeutic approaches to preserve islet mass in type 2 diabetes

1 reference

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12 December 2020

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Beta-cell differentiation from a human pancreatic cell line in vitro and in vivo

1 reference

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12 December 2020

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Biological effects of Spirometra erinacei plerocercoids in several species of rodents.

1 reference

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12 December 2020

based on heuristic

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Glucagon-like peptide-1 and glucose-dependent insulin-releasing polypeptide plasma levels in response to nutrients

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

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Uncovering the pharmacology of the G protein-coupled receptor GPR40: high apparent constitutive activity in guanosine 5'-O-(3-[35S]thio)triphosphate binding studies reflects binding of an endogenous agonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

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Free fatty acids inhibit serum deprivation-induced apoptosis through GPR120 in a murine enteroendocrine cell line STC-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

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Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41

1 reference

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12 December 2020

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KMD-3213, a novel, potent, alpha 1a-adrenoceptor-selective antagonist: characterization using recombinant human alpha 1-adrenoceptors and native tissues

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor I (IGF-I)-stimulated pancreatic beta-cell growth is glucose-dependent. Synergistic activation of insulin receptor substrate-mediated signal transduction pathways by glucose and IGF-I in INS-1 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-cell proliferation and apoptosis in the developing normal human pancreas and in hyperinsulinism of infancy

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

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Differences in partial agonist action at cholecystokinin receptors of mouse and rat are dependent on parameters extrinsic to receptor structure: molecular cloning, expression and functional characterization of the mouse type A cholecystokinin recept

1 reference

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12 December 2020

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Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucagon-like peptide-1 but not glucagon-like peptide-2 stimulates insulin release from isolated rat pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth hormone is a growth factor for the differentiated pancreatic beta-cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free fatty acids induce cholecystokinin secretion through GPR120.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Minireview: Glucagon-like peptides regulate cell proliferation and apoptosis in the pancreas, gut, and central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

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Regulation of islet beta-cell proliferation by prolactin in rat islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

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Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation

1 reference

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12 December 2020

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Cloning, functional expression and tissue distribution of human cDNA for the vascular-type vasopressin receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

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Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

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Species differences in the physiological activity of dietary lignan (sesamin and episesamin) in affecting hepatic fatty acid metabolism

1 reference

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12 December 2020

based on heuristic

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Oleic acid interacts with GPR40 to induce Ca2+ signaling in rat islet beta-cells: mediation by PLC and L-type Ca2+ channel and link to insulin release

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

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Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

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Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

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Reduction in voltage-gated K+ currents in primary cultured rat pancreatic beta-cells by linoleic acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted expression of placental lactogen in the beta cells of transgenic mice results in beta cell proliferation, islet mass augmentation, and hypoglycemia.

1 reference

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12 December 2020

based on heuristic

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Free fatty acids administered into the colon promote the secretion of glucagon-like peptide-1 and insulin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18320172

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A single amino-acid difference confers major pharmacological variation between human and rodent 5-HT1B receptors

1 reference

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12 December 2020

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Glucagon-like peptide I reduces postprandial glycemic excursions in IDDM

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Identifiers

10.1007/S00210-007-0250-Y

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18320172%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18320172%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

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