Effect of hyperosmotic conditions on the expression of the betaine-GABA-transporter (BGT-1) in cultured mouse astrocytes (Q46723192)

24 December 2017

title

Effect of hyperosmotic conditions on the expression of the betaine-GABA-transporter (BGT-1) in cultured mouse astrocytes (English)

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24 December 2017

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Mads Olsen

1

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24 December 2017

Alan Sarup

series ordinal

2

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24 December 2017

Orla M Larsson

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3

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24 December 2017

Arne Schousboe

series ordinal

4

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24 December 2017

publication date

1 June 2005

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24 December 2017

published in

Neurochemical Research

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24 December 2017

volume

30

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24 December 2017

issue

6-7

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24 December 2017

page(s)

855-865

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24 December 2017

https://scigraph.springernature.com/pub.10.1007/s11064-005-6879-3

exact match

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cites work

Identification of the second tonicity-responsive enhancer for the betaine transporter (BGT1) gene

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Mutations within an intramembrane leucine heptad repeat disrupt oligomer formation of the rat GABA transporter 1.

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Cell volume regulation: a review of cerebral adaptive mechanisms and implications for clinical treatment of osmolal disturbances. I

21 January 2018

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Osmoregulation of betaine transport in mammalian renal medullary cells

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The tonicity-sensitive element that mediates increased transcription of the betaine transporter gene in response to hypertonic stress

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Purification and identification of the functional sodium- and chloride-coupled gamma-aminobutyric acid transport glycoprotein from rat brain.

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Survey of osmolytes in renal cell lines

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Effects of hypernatremia on organic brain osmoles

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A light and electron microscopic study of betaine/GABA transporter distribution in the monkey cerebral neocortex and hippocampus

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12 December 2020

Uptake and metabolism of γ-aminobutyric acid by neurones and glial cells

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12 December 2020

GABA transporter heterogeneity: pharmacology and cellular localization

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p38 kinase activity is essential for osmotic induction of mRNAs for HSP70 and transporter for organic solute betaine in Madin-Darby canine kidney cells

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12 December 2020

Changes in GABA transporters in the rat hippocampus after kainate-induced neuronal injury: decrease in GAT-1 and GAT-3 but upregulation of betaine/GABA transporter BGT-1

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12 December 2020

Gene expression of taurine transporter and taurine biosynthetic enzymes in brain of rats with acute or chronic hyperosmotic plasma. A comparative study with gene expression of myo-inositol transporter, betaine transporter and sorbitol biosynthetic e

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12 December 2020

Asymmetrical response of p38 kinase activation to volume changes in primary rat astrocytes

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12 December 2020

Expression of betaine transporter mRNA: its unique localization and rapid regulation in rat kidney

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Selective inhibitors of GABA uptake: synthesis and molecular pharmacology of 4-N-methylamino-4,5,6,7-tetrahydrobenzo[d]isoxazol-3-ol analogues

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Sodium-dependent neurotransmitter transporters: oligomerization as a determinant of transporter function and trafficking

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Cloning and expression of a betaine/GABA transporter from human brain

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GABA uptake inhibitors: relevance to antiepileptic drug research

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Molecular cloning and functional characterization of a GABA/betaine transporter from human kidney

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Plasma membrane GABA transporters reside on distinct vesicles and undergo rapid regulated recycling.

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Oligomerization of the human serotonin transporter and of the rat GABA transporter 1 visualized by fluorescence resonance energy transfer microscopy in living cells.

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Problems in the understanding of cell volume regulation

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12 December 2020

Differential activation of system A and betaine/GABA transport in MDCK cell membranes by hypertonic stress

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12 December 2020

Expression of a mouse brain cDNA encoding novel gamma-aminobutyric acid transporter

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12 December 2020

Gene expression of the transporters and biosynthetic enzymes of the osmolytes in astrocyte primary cultures exposed to hyperosmotic conditions

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GABA transporters and GABA-transaminase as drug targets

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12 December 2020

Induction of BGT-1 and amino acid system A transport activities in endothelial cells exposed to hyperosmolarity

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GABA transporters as drug targets for modulation of GABAergic activity

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First demonstration of a functional role for central nervous system betaine/{gamma}-aminobutyric acid transporter (mGAT2) based on synergistic anticonvulsant action among inhibitors of mGAT1 and mGAT2.

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Uptake and metabolism of glutamate in astrocytes cultured from dissociated mouse brain hemispheres

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Inhibition of gamma-aminobutyric acid uptake: anatomy, physiology and effects against epileptic seizures

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Tonicity-responsive enhancer binding protein, a rel-like protein that stimulates transcription in response to hypertonicity

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Characterization of the major brain osmolytes that accumulate in salt-loaded rats

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12 December 2020

Correlation between anticonvulsant activity and inhibitory action on glial gamma-aminobutyric acid uptake of the highly selective mouse gamma-aminobutyric acid transporter 1 inhibitor 3-hydroxy-4-amino-4,5,6,7-tetrahydro-1,2-benzisoxazole and its N-

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12 December 2020

GAT-1, a high-affinity GABA plasma membrane transporter, is localized to neurons and astroglia in the cerebral cortex.

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Role of the betaine/GABA transporter (BGT-1/GAT2) for the control of epilepsy

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Transport and Metabolism of 7-Aminobutyric Acid in Neurons and Glia: Implications for Epilepsy

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12 December 2020

Localization of messenger RNAs encoding three GABA transporters in rat brain: an in situ hybridization study

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12 December 2020

Role of astrocytic transport processes in glutamatergic and GABAergic neurotransmission.

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12 December 2020

Role of desensitization and subunit expression for kainate receptor-mediated neurotoxicity in murine neocortical cultures.

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12 December 2020

Mutual inhibition kinetic analysis of gamma-aminobutyric acid, taurine, and beta-alanine high-affinity transport into neurons and astrocytes: evidence for similarity between the taurine and beta-alanine carriers in both cell types.

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12 December 2020

Medium tonicity regulates expression of the Na(+)- and Cl(-)-dependent betaine transporter in Madin-Darby canine kidney cells by increasing transcription of the transporter gene

1 reference

12 December 2020

Induction of betaine-gamma-aminobutyric acid transport activity in porcine chondrocytes exposed to hypertonicity

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12 December 2020

Osmolyte strategy in human monocytes and macrophages: involvement of p38MAPK in hyperosmotic induction of betaine and myoinositol transporters.

1 reference

12 December 2020

Cloning of a Na(+)- and Cl(-)-dependent betaine transporter that is regulated by hypertonicity

1 reference

12 December 2020

10.1007/S11064-005-6879-3

Identifiers

DOI

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24 December 2017

PubMed ID

16187220

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24 December 2017