Dopamine depletion does not protect against acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in vivo. (Q46750122)

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8 January 2020

title

Dopamine depletion does not protect against acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in vivo (English)

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8 January 2020

author name string

Daphne M Hasbani

1

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8 January 2020

Francisco A Perez

2

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8 January 2020

Richard D Palmiter

3

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8 January 2020

Karen L O'Malley

4

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8 January 2020

language of work or name

English

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publication date

1 October 2005

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8 January 2020

published in

Journal of Neuroscience

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8 January 2020

volume

25

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8 January 2020

page(s)

9428-9433

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8 January 2020

issue

41

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describes a project that uses

8 January 2020

ImageQuant

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11 June 2022

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cites work

Cytotoxic and genotoxic potential of dopamine

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12 December 2020

Dopamine oxidation alters mitochondrial respiration and induces permeability transition in brain mitochondria: implications for Parkinson's disease.

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Tyrosine hydroxylase is inactivated by catechol-quinones and converted to a redox-cycling quinoprotein: possible relevance to Parkinson's disease.

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Cocaine reward and MPTP toxicity: alteration by regional variant dopamine transporter overexpression.

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Dopamine-deficient mice are hypersensitive to dopamine receptor agonists.

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The parkinsonism-inducing drug 1-methyl-4-phenylpyridinium triggers intracellular dopamine oxidation. A novel mechanism of toxicity

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12 December 2020

Role of oxidative changes in the degeneration of dopamine terminals after injection of neurotoxic levels of dopamine

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Chronic systemic pesticide exposure reproduces features of Parkinson's disease

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Glutamatergic influences on the basal ganglia.

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12 December 2020

Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease

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The role of glial cells in Parkinson's disease

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12 December 2020

Induction of stereotypy in dopamine-deficient mice requires striatal D1 receptor activation

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12 December 2020

Are dopamine, norepinephrine, and serotonin precursors of biologically reactive intermediates involved in the pathogenesis of neurodegenerative brain disorders?

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12 December 2020

Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease.

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12 December 2020

Rotenone destroys dopaminergic neurons and induces parkinsonian symptoms in rats

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12 December 2020

Subcutaneous rotenone exposure causes highly selective dopaminergic degeneration and alpha-synuclein aggregation.

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12 December 2020

Fine Structure and Biochemical Mechanisms Underlying Nigrostriatal Inclusions and Cell Death after Proteasome Inhibition

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Dynamic regulation of the dopamine transporter.

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The PARK8 locus in autosomal dominant parkinsonism: confirmation of linkage and further delineation of the disease-containing interval

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Genetic clues to the pathogenesis of Parkinson's disease

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Firing properties of dopamine neurons in freely moving dopamine-deficient mice: effects of dopamine receptor activation and anesthesia

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Differential gene expression induced by chronic levodopa treatment in the striatum of rats with lesions of the nigrostriatal system

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12 December 2020

Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease

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12 December 2020

Lack of evidence supporting a role for dopamine in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity

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12 December 2020

Effects of amfonelic acid, alpha-methyltyrosine, Ro 4-1284 and haloperidol pretreatment on the depletion of striatal dopamine by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice

1 reference

12 December 2020

Striatal dihydroxyphenylalanine decarboxylase and tyrosine hydroxylase protein in idiopathic Parkinson's disease and dominantly inherited olivopontocerebellar atrophy

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Studies on species sensitivity to the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Part 1: Systemic administration.

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12 December 2020

Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic

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12 December 2020

Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1 reference

12 December 2020

Role of oxidation in the neurotoxic effects of intrastriatal dopamine injections

1 reference

12 December 2020

Intricate regulation of tyrosine hydroxylase activity and gene expression

1 reference

12 December 2020

Estimation of the number of somatostatin neurons in the striatum: an in situ hybridization study using the optical fractionator method

1 reference

12 December 2020

In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining

1 reference

12 December 2020

Inactivation of tyrosine hydroxylase by nitration following exposure to peroxynitrite and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

1 reference

12 December 2020

10.1523/JNEUROSCI.0130-05.2005

Identifiers

DOI

1 reference

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