Effects of gpx4 haploid insufficiency on GPx4 activity, selenium concentration, and paraquat-induced protein oxidation in murine tissues (Q46772254)

25 December 2017

title

Effects of gpx4 haploid insufficiency on GPx4 activity, selenium concentration, and paraquat-induced protein oxidation in murine tissues (English)

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25 December 2017

author name string

Michael S Scimeca

1

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25 December 2017

Donald J Lisk

2

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25 December 2017

Tomas Prolla

3

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25 December 2017

Xin Gen Lei

4

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25 December 2017

language of work or name

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1 November 2005

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25 December 2017

Experimental Biology and Medicine

published in

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25 December 2017

volume

230

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25 December 2017

issue

10

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25 December 2017

page(s)

709-714

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25 December 2017

Phospholipid hydroperoxide glutathione peroxidase is a selenoenzyme distinct from the classical glutathione peroxidase as evident from cDNA and amino acid sequencing.

cites work

1 reference

https://api.crossref.org/works/10.1177%2F153537020523001003

Rat phospholipid-hydroperoxide glutathione peroxidase. cDNA cloning and identification of multiple transcription and translation start sites.

21 January 2018

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Import into mitochondria of phospholipid hydroperoxide glutathione peroxidase requires a leader sequence.

21 January 2018

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https://api.crossref.org/works/10.1177%2F153537020523001003

Biological significance of phospholipid hydroperoxide glutathione peroxidase (PHGPx, GPx4) in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523001003

The selenoenzyme phospholipid hydroperoxide glutathione peroxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523001003

The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523001003

Dual function of the selenoprotein PHGPx during sperm maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523001003

Male fertility is linked to the selenoprotein phospholipid hydroperoxide glutathione peroxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523001003

The selenoenzyme phospholipid hydroperoxide glutathione peroxidase controls the activity of the 15-lipoxygenase with complex substrates and preserves the specificity of the oxygenation products

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523001003

Suppression of leukotriene formation in RBL-2H3 cells that overexpressed phospholipid hydroperoxide glutathione peroxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523001003

Embryonic fibroblasts from Gpx4+/- mice: a novel model for studying the role of membrane peroxidation in biological processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523001003

Superoxide- and singlet oxygen-catalyzed lipid peroxidation as a possible mechanism for paraquat (methyl viologen) toxicity.

21 January 2018

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https://api.crossref.org/works/10.1177%2F153537020523001003

Carbonyl assays for determination of oxidatively modified proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523001003

Impacts of glutathione peroxidase-1 knockout on the protection by injected selenium against the pro-oxidant-induced liver aponecrosis and signaling in selenium-deficient mice.

21 January 2018

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Transgenic mice overexpressing glutathione peroxidase 4 are protected against oxidative stress-induced apoptosis

21 January 2018

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Abnormal thalamocortical pathfinding and terminal arbors lead to enlarged barrels in neonatal GAP-43 heterozygous mice

21 January 2018

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Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1 alpha

21 January 2018

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A novel functional role for apolipoprotein B in male infertility in heterozygous apolipoprotein B knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523001003

Knockout of cellular glutathione peroxidase affects selenium-dependent parameters similarly in mice fed adequate and excessive dietary selenium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F153537020523001003

Genetic background but not metallothionein phenotype dictates sensitivity to cadmium-induced testicular injury in mice

21 January 2018

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10.1177/153537020523001003

21 January 2018

Identifiers

DOI

1 reference

25 December 2017

PubMed ID

16246897

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25 December 2017